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Beilstein J. Org. Chem. 2026, 22, 905–914, doi:10.3762/bjoc.22.71
Graphical Abstract
Scheme 1: Various transition-metal-catalyzed coupling reactions involving aryl halides.
Scheme 2: Synthetic strategy for preparing fused lactams.
Figure 1: Nuclear Overhauser effect (NOE) correlations in products (a) 3ab, (b) 3ac, (c) 3ad, (d) 3aj, and (e...
Scheme 3: Detection of the intermediate Int-1ad in the annulation reaction of 1a with 1-bromo-5-tert-butyl-2-...
Scheme 4: Stepwise formation of C–C and C–N bonds during the annulation reaction.
Scheme 5: Plausible reaction mechanism for the sequential C–H/N–H functionalization reaction.
Beilstein J. Org. Chem. 2024, 20, 3256–3262, doi:10.3762/bjoc.20.269
Figure 1: Structures of multiply fused heterocyclic compounds composed of pyridine rings.
Scheme 1: Synthesis of C–H arylation precursors 1a–c.
Scheme 2: Palladium-catalyzed intramolecular direct arylation for synthesizing 8a and 8b and the X-ray crysta...