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Beilstein J. Org. Chem. 2025, 21, 1010–1017, doi:10.3762/bjoc.21.82
Graphical Abstract
Figure 1: Development of drugs based on pyrrolopyrimidines: A: Cadeguomycin. B: Tubercidin. C: Toyocamycin. D...
Scheme 1: Synthesis of 3a–h. Conditions: i) Br2 (1.0 equiv), Ac2O (1.5 equiv), AcOH, 25 °C, 1 h [25]; ii) aryl ac...
Scheme 2: C–N cross-coupling/hydroamination reaction.
Scheme 3: Synthesis of 4a–m. Conditions: Pd(OAc)2 (5 mol %), DPEphos (5 mol %), K3PO4 (3 equiv), DMA, 100 °C,...
Figure 2: UV–vis absorption (left) and emission (right, λex = 300 nm) spectra of compounds 4a, 4j, 4k, 4l, an...