2 article(s) from Villinger, Alexander
Graphical Abstract
Figure 1: Pharmacologically relevant furoindoles.
Scheme 1: Synthesis of benzo[4,5]furo[3,2-b]indoles 5a–j. Conditions: (i) 1.2 equiv 2-bromophenylboronic acid...
Figure 2: Ortep of 5c (propability of ellipsoids: 45%).
Figure 3: Diindolofurans 6a–e.
Figure 4: Illustration of binding poses of selected inhibitors for the ENPP1 homology model: (a): suramin, (b...
Figure 5: 3D poses of docked selected inhibitors inside homology model of ENPP3. (a): suramin, (b): 5e, (c): ...
Graphical Abstract
Scheme 1: Reagents and conditions: (i) CH3CN, K2CO3, rt, 24 h.
Scheme 2: Synthesis of compounds 3–8. Reagents and conditions: (i): CH3CN, K2CO3, rt, 24 h. In the case of 3-...
Figure 1: Synthesized compounds 3, 4, 6, 7.
Figure 2: Plausible reaction mechanism.
Scheme 3: The influence of K+ on the product free energy.