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Beilstein J. Org. Chem. 2026, 22, 1168–1195, doi:10.3762/bjoc.22.94
Graphical Abstract
Figure 1: Some important examples of FDA approved anticancer drugs.
Figure 2: Some natural products based anticancer drugs.
Figure 3: Chemical structures of isomeric triazole rings.
Figure 4: FDA approved drugs containing an 1,2,3- or 1,2,4-triazole moiety.
Figure 5: Anticancer compounds with an 1,2,3- or 1,2,4-triazole moiety.
Figure 6: Types of triazole containing hybrids.
Figure 7: Structures of diverse coumarin–1,2,3-triazole hybrids 20–29.
Figure 8: Structures of diverse coumarin–1,2,3-triazole hybrids 30–34.
Figure 9: Structures of diverse coumarin–1,2,4-triazole hybrids 35–41.
Figure 10: Structures of indole–triazole hybrids.
Figure 11: Structures of indoly–1,2,4-triazole hybrids and indolin-2-one-1,2,4-triazoles.
Figure 12: Structures of quinoline/quinolone–triazole hybrids 60–68.
Figure 13: Structures of quinoline/quinolone–triazole hybrids 69–72.
Figure 14: Structures of chalcone–triazole hybrids 73–79.
Figure 15: Structures of chalcone–triazole hybrids 80–85.
Figure 16: Structures of 1,2,3-triazole–pyridine derivatives 86–89.
Figure 17: Structures of 1,2,3-triazolyl–3-cyanopyridine hybrids 90–96.
Figure 18: Structures of pyridine/pyrimidine–triazole hybrids 97–102.
Figure 19: Structures of bistriazolyl-2-mercaptobenzimidazole 103, benzimidazole-1,2,3-triazole conjugates 104...
Figure 20: Structures of botulin-based triazole hybrids 109–116.