New modification of the Perkow reaction: halocarboxylate anions as leaving groups in 3-acyloxyquinoline- 2,4(1H,3H)-dione compounds

• Oldřich Paleta,
• Karel Pomeisl,
• Stanislav Kafka,
• Antonín Klásek and
• Vladislav Kubelka

Beilstein J. Org. Chem. 2005, 1, No. 17, doi:10.1186/1860-5397-1-17

• observed reaction to be due to the increased electron-withdrawing character of the acyl moiety. According to Scheme 2, the reaction of 3-(halogenoacyloxy)quinoline-2,4(1H,3H)-diones 4-6 with triethyl phosphite gave two kinds of products: the product of the Perkow reaction (8) and 1-alkyl-4-ethoxy-quinolin