The first preparative solution phase synthesis of melanotan II

• Vladimir V. Ryakhovsky,
• Georgy A. Khachiyan,
• Nina F. Kosovova,
• Elena F. Isamiddinova and
• Andrey S. Ivanov

Beilstein J. Org. Chem. 2008, 4, No. 39, doi:10.3762/bjoc.4.39

• Vladimir V. Ryakhovsky Georgy A. Khachiyan Nina F. Kosovova Elena F. Isamiddinova Andrey S. Ivanov R&D Dept., Pharm-Sintez, 38 Shosse Entusiastov, 111123 Moscow, Russia 10.3762/bjoc.4.39 Abstract Melanotan II is a synthetic cyclic heptapeptide used to prevent a sunlight-induced skin cancer by