An exceptional P-H phosphonite: Biphenyl- 2,2'-bisfenchylchlorophosphite and derived ligands (BIFOPs) in enantioselective copper- catalyzed 1,4-additions

• T. Kop-Weiershausen,
• J. Lex,
• J.-M. Neudörfl and
• B. Goldfuss

Beilstein J. Org. Chem. 2005, 1, No. 6, doi:10.1186/1860-5397-1-6

• ; Introduction Chiral monodentate phosphorus ligands with C2-symmetric diol backbones, e.g. with the prominent BINOLs or TADDOLs, are fundamental for the construction of efficient enantioselective transition metal catalysts, especially for copper-catalyzed 1,4-additions. [1][2][3][4][5][6][7][8][9][10][11][12