Iridium-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes with secondary amine nucleophiles

• Dingqiao Yang,
• Ping Hu,
• Yuhua Long,
• Yujuan Wu,
• Heping Zeng,
• Hui Wang and
• Xiongjun Zuo

Beilstein J. Org. Chem. 2009, 5, No. 53, doi:10.3762/bjoc.5.53

• metal catalysts may be used for asymmetric ring-opening reactions of oxabicyclic alkenes. These include complexes of copper [20][21][22][23][24][25], palladium [14][15][26][27][28][29][30][31], iron [32], and nickel [33][34][35][36]. Recently, we reported for the first time iridium-catalyzed asymmetric

• -catalyzed asymmetric ring-opening of oxabenzonorbornadiene with a wide range of nucleophiles including thiols [10], phenols [11], organoboronic acids [12][13], dialkylzincs [14][15], carboxylates [16], sulfur nucleophiles [17], and various amines [18][19]. In addition to rhodium catalysts, other transition

Pd/C- Mediated synthesis of indoles in water

• Mohosin Layek,
• Udaya Lakshmi,
• Dipak Kalita,
• Deepak K. Barange,
• Aminul Islam,
• K. Mukkanti and
• Manojit Pal

Beilstein J. Org. Chem. 2009, 5, No. 46, doi:10.3762/bjoc.5.46

• analogues. A large number of methods [9][10][11][12] have been reported for the construction of indole ring many of which are mediated by transition metal catalysts. Among these methods palladium mediated protocols have gain considerable interest [13]. In our effort towards the development of palladium

A biphasic oxidation of alcohols to aldehydes and ketones using a simplified packed- bed microreactor

• Andrew Bogdan and
• D. Tyler McQuade

Beilstein J. Org. Chem. 2009, 5, No. 17, doi:10.3762/bjoc.5.17

• potential as continuous flow processes. Realizing this, we developed a catalytic packed-bed microreactor that could be used for the continuous flow oxidation of alcohols to aldehydes or ketones. Oxidations that do not require transition metal catalysts are particularly appealing since there is neither

An exceptional P-H phosphonite: Biphenyl- 2,2'-bisfenchylchlorophosphite and derived ligands (BIFOPs) in enantioselective copper- catalyzed 1,4-additions

• T. Kop-Weiershausen,
• J. Lex,
• J.-M. Neudörfl and
• B. Goldfuss

Beilstein J. Org. Chem. 2005, 1, No. 6, doi:10.1186/1860-5397-1-6

• ; Introduction Chiral monodentate phosphorus ligands with C2-symmetric diol backbones, e.g. with the prominent BINOLs or TADDOLs, are fundamental for the construction of efficient enantioselective transition metal catalysts, especially for copper-catalyzed 1,4-additions. [1][2][3][4][5][6][7][8][9][10][11][12