Benzyne arylation of oxathiane glycosyl donors

• Martin A. Fascione and
• W. Bruce Turnbull

Beilstein J. Org. Chem. 2010, 6, No. 19, doi:10.3762/bjoc.6.19

• sulfur arylation, glycosylation of acetate ions proceeded with high levels of stereoselectivity to afford α-glycosyl acetates in a ‘one-pot’ reaction, even in the presence of alternative acceptor alcohols. Keywords: benzyne; 1,2-cis-glycosides; glycosyl acetates; oxathiane glycosyl donors

One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds

• Fernando de C. da Silva,
• Mauricio G. Fonseca,
• Renata de S. Rianelli,
• Anna C. Cunha,
• Maria C. B. V. de Souza and
• Vitor F. Ferreira

Beilstein J. Org. Chem. 2008, 4, No. 45, doi:10.3762/bjoc.4.45

• compounds in a one-pot reaction. Results and Discussion The substituted pyrroles 7a–n were prepared according to the synthetic pathways described in Scheme 1. α-Diazocarbonyl compounds ethyl 2-diazoacetoacetate (1), 3-diazopentane-2,4-dione (2) and diazomalonaldehyde (3) were treated with a catalytic

New acylides: synthesis of 3-O-[γ-(4-oxo-2-aryl- thiazolidin- 3-yl)butyryl]erythromycin A derivatives

• Deepa Pandey,
• Wahajul Haq and
• Seturam B. Katti

Beilstein J. Org. Chem. 2008, 4, No. 14, doi:10.3762/bjoc.4.14

• desired γ-aminoacylide derivative 3 was obtained in ~96% yield. The amino group (of compound 3) thus obtained was utilized to append the desired thiazolidinone described below. The desired thiazolidinone was generated on 3 by dicyclohexylcarbodiimide-mediated three-component one-pot reaction, in which the

Combining two-directional synthesis and tandem reactions, part 11: second generation syntheses of (±)-hippodamine and (±)-epi-hippodamine

• Annabella F. Newton,
• Martin Rejzek,
• Marie-Lyne Alcaraz and
• Robert A. Stockman

Beilstein J. Org. Chem. 2008, 4, No. 4, doi:10.1186/1860-5397-4-4

• addition. Summary of our efforts to effect quinolizidine formation in a one-pot reaction. Supporting Information Supporting Information File 20: Experimental. Experimental procedures for compounds 4,6,7,9. Acknowledgements The authors wish to thank Leverhulme Trust (MR), AstraZeneca (AFN, CASE award) and

Synthesis of phosphorothioates using thiophosphate salts

• Babak Kaboudin and
• Fatemeh Farjadian

Beilstein J. Org. Chem. 2006, 2, No. 4, doi:10.1186/1860-5397-2-4

• benzoyl chloride (a hard electrophile), gave the O-acylation product. A simple, efficient, and general method has been developed for the synthesis of phosphorothioates through a one-pot reaction of alkyl halides with the mixture of diethyl phosphite in the presence of triethylamine/sulfur/and acidic

Total syntheses of oxygenated brazanquinones via regioselective homologous anionic Fries rearrangement of benzylic O-carbamates

• Glaucia Barbosa Candido Alves Slana,
• Mariângela Soares de Azevedo,
• Rosângela Sabattini Capella Lopes,
• Cláudio Cerqueira Lopes and
• Jari Nobrega Cardoso

Beilstein J. Org. Chem. 2006, 2, No. 1, doi:10.1186/1860-5397-2-1

• , [12] the benzoylbenzofurans 5a-5d, were prepared in one-pot reaction from α-bromoacetophenone 6 and ortho-hydroxybenzaldehydes 7a-7d in excellent yields (90–96%). Reduction of benzoylbenzofurans 5a-5d in the presence of NaBH4 yielded the secondary alcohols 8a-8d, which upon treatment with N,N