Beilstein J. Org. Chem.2020,16, 2671–2678, doi:10.3762/bjoc.16.217
-nucleophile; CF3-aldimine; fluorinated propargylamine; Introduction
In recent years, substitution of hydrogen by fluorine atoms or fluorine-containing groups usually provides unexpected biological and physicochemical properties, which thus has become an established approach for the development of
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Graphical Abstract
Figure 1:
Anti-HIV compound containing a trifluoromethylpropargylamine moiety.