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Search for "ChIP-Seq" in Full Text gives 1 result(s) in Beilstein Journal of Organic Chemistry.

A systems-based framework to computationally describe putative transcription factors and signaling pathways regulating glycan biosynthesis

  • Theodore Groth,
  • Rudiyanto Gunawan and
  • Sriram Neelamegham

Beilstein J. Org. Chem. 2021, 17, 1712–1724, doi:10.3762/bjoc.17.119

Graphical Abstract
  • pathways is largely unknown. In this work, we performed data mining of TF–glycogene relationships from the Cistrome Cancer database (DB), which integrates chromatin immunoprecipitation sequencing (ChIP-Seq) and RNA-Seq data to constitute regulatory relationships. In total, we observed 22,654 potentially
  • relationships, the starting point for experimental system-wide validation. Keywords: ChIP-Seq; glycoinformatics; glycosylation; TCGA transcription factor; Introduction The glycan signatures of cells and tissue are controlled by the expression pattern of 300–350 glycosylating-related genes that are together
  • [12], and by the manual curation of various human glycogenes into pathways at GlycoEnzDB (https://virtualglycome.org/GlycoEnzDB, Figure 1B). Here, the Cistrome Cancer DB uses TF–gene binding data from previously published chromatin immunoprecipitation sequencing (ChIP-Seq) studies for various cell
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Published 22 Jul 2021
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