Transformation of the cyclohexane ring to the cyclopentane fragment of biologically active compounds

• Natalya Akhmetdinova,
• Ilgiz Biktagirov and
• Liliya Kh. Faizullina

Beilstein J. Org. Chem. 2025, 21, 2416–2446, doi:10.3762/bjoc.21.185

• approach to the synthesis of taiwaniaquinoids was applied by Gademann et al. [13][42] for the transition from an abietane structure to a five-membered system using a rearrangement of benzilic acid. The strong base promoted the intramolecular attack of the α-hydroxy group in compound 59 on the keto group at

Opportunities and challenges for the sustainable production of structurally complex diterpenoids in recombinant microbial systems

• Katarina Kemper,
• Max Hirte,
• Markus Reinbold,
• Monika Fuchs and
• Thomas Brück

Beilstein J. Org. Chem. 2017, 13, 845–854, doi:10.3762/bjoc.13.85

• performed in vivo substrate promiscuity tests following a combinatorial approach [41][66]. The resulting products entailed pimarane- and abietane-type diterpenes as well as the trans-clerodane type diterpene kolavenol, a putative intermediate in the salvinorin A biosynthesis. Other bifunctional diterpene

Decandrinin, an unprecedented C₉-spiro-fused 7,8-seco-ent-abietane from the Godavari mangrove Ceriops decandra

• Hui Wang,
• Min-Yi Li,
• Félix Zongwe Katele,
• Tirumani Satyanandamurty,
• Jun Wu and
• Gerhard Bringmann

Beilstein J. Org. Chem. 2014, 10, 276–281, doi:10.3762/bjoc.10.23

• , University of Würzburg, Am Hubland, Würzburg 97074, Germany Government Degree College at Amadala valasa, Srikakulam District, Andhra Pradesh 532185, India 10.3762/bjoc.10.23 Abstract Decandrinin (1), an unprecedented C9-spiro-fused 7,8-seco-ent-abietane, was obtained from the bark of an Indian mangrove

• combination with quantum-chemical calculations. Decandrinin is the first 7,8-seco-ent-abietane. Keywords: abietane; absolute configuration; Ceriops decandra; circular dichroism; decandrinin; Rhizophoraceae; Introduction Ceriops decandra is a mangrove of the family Rhizophoraceae. It is widely distributed

• , five kauranes, and 16 lupanes). Recently, some of us have reported on the isolation of eleven new diterpenes from this plant, named decandrins A–K [7], of which nine belong to the group of abietanes. Seco-abietane diterpenoids are a small group of natural products. To date, a total of 58 such compounds