Investigations of alkynylbenziodoxole derivatives for radical alkynylations in photoredox catalysis

• Yue Pan,
• Kunfang Jia,
• Yali Chen and
• Yiyun Chen

Beilstein J. Org. Chem. 2018, 14, 1215–1221, doi:10.3762/bjoc.14.103

• to study the radical acceptor and oxidative quencher reactivity of alkynylbenziodoxoles, in which unsubstituted alkynylbenziodoxoles played balancing roles in both processes, while electron-rich benziodoxole derivatives demonstrate synthetic advantages in some cases. Keywords: acyl radical; alkyl

• radical; alkynylbenziodoxoles; photoredox catalysis; radical alkynylation; Introduction The introduction of the alkynyl group to organic molecules is an important synthetic transformation in organic synthesis [1][2][3][4]. Recently, cyclic iodine(III) reagents (CIR)-substituted alkynes

• , alkynylbenziodoxoles, were developed with readily preparation and shelf-stableness [5][6][7][8][9][10]. The alkynylbenziodoxoles were first synthesized by the Ochiai group, and later studied by Waser and other groups for the use in electrophilic alkynylation reactions [11][12][13][14][15][16][17][18]. In 2012, the Li