Beilstein J. Org. Chem.2014,10, 141–149, doi:10.3762/bjoc.10.11
-oxo-5-phenyl-3H-isoindole-4-carboxylate (40).
Keywords: aminopyranes; arylbenzoic acid; DABCO; L-proline; multicomponent; tetrahydronaphthalene; three-component reaction; Introduction
The reaction of arylidenemalononitriles with active methyl and methylene compounds was extensively utilized for the
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Graphical Abstract
Scheme 1:
Reaction of active methylenenitriles with α,β-unsaturated ketones 1.