Beilstein J. Org. Chem.2022,18, 420–428, doi:10.3762/bjoc.18.44
bromopropargylic alcohols and Cs2CO3.
Keywords: acetylenic alcohol; bromoacetylene; 1,3-dioxolan-2-one; phenols; phenoxyketone; Introduction
Due to the relative stability, ease of handling and the presence of reactive sites, bromoacetylenes are widely applied in synthetic organic chemistry. They are known to be
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Graphical Abstract
Scheme 1:
Scope of the reaction of bromopropargylic alcohol 1a and phenols 2b–i.