Synthesis and properties of calix[4]arene telluropodant ethers as Ag⁺ selective sensors and Ag⁺, Hg²⁺ extractants

• Yang Lu,
• Yuanyuan Li,
• Song He,
• Yan Lu,
• Changying Liu,
• Xianshun Zeng and
• Langxing Chen

Beilstein J. Org. Chem. 2009, 5, No. 59, doi:10.3762/bjoc.5.59

• their potential receptor properties for cations, anions and neutral molecules, calixarenes have enjoyed widespread use in various areas of science and technology. One of their successful applications as sensors is in analytical chemistry. They are useful for separations, enrichment, and analyses of

• ionic and neutral molecular species [1][2][3][4]. In particular, the ion-selective electrode (ISE) is an important target in analytical applications [5][6][7][8][9][10]. To improve the ion selectivity of calixarenes, a great deal of effort has been devoted to the design and synthesis of novel

• functionalized calixarenes in recent years [1][2][3][4]. In fact, a large number of calixarene derivatives containing pendant ether, amide, ketonic, ester and crown ether groups have been employed in studies of ISEs sensitive to sodium ions [11][12][13][14][15][16][17][18][19][20], potassium ions [21][22][23][24

Synthesis of deep- cavity fluorous calix[4]arenes as molecular recognition scaffolds

• Maksim Osipov,
• Qianli Chu,
• Steven J. Geib,
• Dennis P. Curran and
• Stephen G. Weber

Beilstein J. Org. Chem. 2008, 4, No. 36, doi:10.3762/bjoc.4.36

• ; organofluorine; (perfluoroalkyl)alkyl aryl ethers; Introduction Calixarenes [1] are one of the most useful types of macrocyclic scaffolds. Since first reported by Zinke and Ziegler [2], calix[4]arenes have been used for a variety of molecular recognition, nanotechnology, and supramolecular applications. These

• extraction of organic substrates into a fluorous liquid phase via hydrogen bonding [21]. Combining the selective nature of fluorous chemistry with the extensive molecular recognition capabilities of calixarenes should generate a scaffold for selective molecular receptors, yet few reports exist that detail

• the synthesis and applications of fluorous calixarenes [22][23][24][25][26]. There are no reports of studies of solubilities of such calixarenes in fluorous solvents. The work reported herein is focused on synthesizing fluorous calixarenes that are easily functionalized for selective molecular