Intramolecular carbonickelation of alkenes

• Rudy Lhermet,
• Muriel Durandetti and
• Jacques Maddaluno

Beilstein J. Org. Chem. 2013, 9, 710–716, doi:10.3762/bjoc.9.81

• Rudy Lhermet Muriel Durandetti Jacques Maddaluno Laboratoire COBRA, CNRS UMR 6014 & FR 3038, Université de Rouen, INSA de Rouen, 1 rue Tesnières, 76821 Mont St Aignan Cedex, France 10.3762/bjoc.9.81 Abstract The efficiency of the intramolecular carbonickelation of substituted allylic ethers and

• skeleton was achieved by using NiBr2bipy catalysis. Keywords: alkenes; carbometallation; carbonickelation; cyclization; Heck-type reaction; nickel catalysis; Introduction Carbometalation is a reaction involving the addition of an organometallic species to a nonactivated alkene or alkyne to form a new

• , efficiently leading to a variety of functionalized 2-arylpyridines [17]. More recently, this nickel-catalyzed reaction provided a convenient and mild method for a one-pot synthesis of substituted benzofurans, chromans and indoles by carbonickelation of alkynes [18]. We finally decided to extend the scope of