Copper catalysis: a constantly evolving field

• Elena Fernández and
• Jaesook Yun

Beilstein J. Org. Chem. 2025, 21, 1477–1479, doi:10.3762/bjoc.21.109

• stereoselective synthesis of chlorocyclopropanes. As guest editors, we are deeply grateful to all contributors for sharing their high-quality work and valuable perspectives. We also thank the referees for their thoughtful evaluations, which helped maintain the scientific rigor of this collection. We hope this

Cu–Bpin-mediated dimerization of 4,4-dichloro-2-butenoic acid derivatives enables the synthesis of densely functionalized cyclopropanes

• Patricia Gómez-Roibás,
• Andrea Chaves-Pouso and
• Martín Fañanás-Mastral

Beilstein J. Org. Chem. 2025, 21, 877–883, doi:10.3762/bjoc.21.71

• versatile building blocks for the stereoselective synthesis of chlorocyclopropanes. Keywords: chlorocyclopropanes; copper; cyclization; 4,4-dichloro-2-butenoic acid derivatives; dimerization; Introduction In the last years our group has been focused on the development of catalytic methodologies for the

• aliphatic gem-dichloride, we explored the feasibility of a base-mediated formation of chlorocyclopropanes (Table 2). Evaluation of bases such as metal tert-butoxides, phosphates, acetates, and organic amines resulted in either low conversion or decomposition of 2 (see Supporting Information File 1 for