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Search for "chloroxime" in Full Text gives 2 result(s) in Beilstein Journal of Organic Chemistry.

Conjugated nitrosoalkenes as Michael acceptors in carbon–carbon bond forming reactions: a review and perspective

  • Yaroslav D. Boyko,
  • Valentin S. Dorokhov,
  • Alexey Yu. Sukhorukov and
  • Sema L. Ioffe

Beilstein J. Org. Chem. 2017, 13, 2214–2234, doi:10.3762/bjoc.13.220

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  • used as a key stage to construct an important C(7)–C(8) connection in the total synthesis of (+/−)-myrioneurinol (Scheme 15) [34][35]. α-Chloroxime TBS ether 43 (prepared in 10 steps from δ-valerolactam) reacted with a dimethyl malonate anion under Denmark’s conditions via intermediate NSA9 to give the
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Published 23 Oct 2017

The rapid generation of isothiocyanates in flow

  • Marcus Baumann and
  • Ian R. Baxendale

Beilstein J. Org. Chem. 2013, 9, 1613–1619, doi:10.3762/bjoc.9.184

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  • chemical transformation which typically eliminates the requirements for any conventional work-up or purification of the reaction stream. Keywords: chloroxime; dipolar cycloaddition; flow chemistry; flow synthesis; immobilised reagents; isothiocyanate; nitrile oxide; Introduction Flow based chemical
  • weak base and a functionalised thiourea) placed as a 1:1-mixture within a single glass reactor cartridge (Scheme 2). The immobilised base affects the in situ formation of the reactive nitrile oxide from the chloroxime which is immediately captured by the local tethered thiocarbonyl dipolarophile
  • for trapping even the small quantities of polar impurities within the matrix thus allowing for the isolation of the desired isothiocyanate product in high purity after only simple solvent removal. Results and Discussion Initially a set of batch experiments was performed using (4-bromophenyl)chloroxime
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Published 08 Aug 2013
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