Aromatic C–H bond functionalization through organocatalyzed asymmetric intermolecular aza-Friedel–Crafts reaction: a recent update

• Anup Biswas

Beilstein J. Org. Chem. 2023, 19, 956–981, doi:10.3762/bjoc.19.72

• indolones 69. Further broadening of the substrate scope was achieved by changing the aryl substituent attached to the pyrazole ring nitrogen. For enantioenrichment of the products, the presence of a methyl group at the C3 position of the pyrazole ring was obligatory. One example was included with a phenyl

Recent developments in enantioselective photocatalysis

• Callum Prentice,
• James Morrisson,
• Andrew D. Smith and
• Eli Zysman-Colman

Beilstein J. Org. Chem. 2020, 16, 2363–2441, doi:10.3762/bjoc.16.197

• recent developments and a particular interest in the proposed mechanisms for each. With the aim of understanding the scope of each strategy, to help guide and inspire further innovation in this field. Keywords: enantioenrichment; enantionselective catalysis; enantioselective photocatalysis

Towards racemizable chiral organogelators

• Jian Bin Lin,
• Debarshi Dasgupta,
• Seda Cantekin and
• Albertus P. H. J. Schenning

Beilstein J. Org. Chem. 2010, 6, 960–965, doi:10.3762/bjoc.6.107

• the base DBU (1,8-diazabicyclo[5.4.0]undec-7-ene). Interestingly, a single solid chiral state from a nearly racemic mixture of this phenylglycinamide derivative was observed by so-called attrition-enhanced solid-phase enantioenrichment [18]. In order to obtain a molecule that is able to form a gel

• organogelators. Remarkably, our pure enantiomeric gelator could not be racemized in the gel phase, while racemization takes place in the self-assembled fiber state. We are currently studying this class of organogelator for the creation of responsive gels and attrition-enhanced solid-phase enantioenrichment

Continuous flow enantioselective arylation of aldehydes with ArZnEt using triarylboroxins as the ultimate source of aryl groups

• Julien Rolland,
• Xacobe C. Cambeiro,
• Carles Rodríguez-Escrich and
• Miquel A. Pericàs

Beilstein J. Org. Chem. 2009, 5, No. 56, doi:10.3762/bjoc.5.56

• system has been optimized for the use of arylboroxins as an atom economical, cheap and readily available source of aryl groups. The simple procedures required for the purification and enantioenrichment of the resulting carbinols converts this flow process into a convenient alternative for the multigram