Synthesis of the Benzo- fused Indolizidine Alkaloid Mimics

• Daniel L. Comins and
• Kazuhiro Higuchi

Beilstein J. Org. Chem. 2007, 3, No. 42, doi:10.1186/1860-5397-3-42

• equiv of formic acid and 4 equiv of triethylamine at 80°C in DMF provided 8a-i in good yields. THF could also be used as a solvent in this reaction. In the case of 1h and 1i, the N-TIPS group was cleaved under the reaction conditions (entries 8,9). To add more points of diversity, the preparation of