Beilstein J. Org. Chem.2011,7, 1656–1662, doi:10.3762/bjoc.7.195
[9] and fungicides [10], and as well as antiviral [11] and antibacterial agents [12]. Pyrazoles are gaining interest as ligands for transition metals, and in the field of materialschemistry [13][14].
Pyrazole and its derivatives can be synthesized by several methods [15]. The most common approach is
PDF
Graphical Abstract
Scheme 1:
Access to 1,3-diaryl-4-halo-1H-pyrazoles from 3-arylsydnones and 2-aryl-1,1-dihalo-1-alkenes.
Beilstein J. Org. Chem.2008,4, No. 11, doi:10.3762/bjoc.4.11
]. Organo-fluorine compounds have also found a significant role in soft materialschemistry such as liquid crystals, photoresist polymers and self assembling monolayers [3].
Allied to this breadth of activity is a steady development in the number and range of fluorination reagents and methodologies. DAST