Lanostane- and cycloartane-type triterpenoids from Abies balsamea oleoresin

• Serge Lavoie,
• Charles Gauthier,
• Jean Legault,
• Sylvain Mercier,
• Vakhtang Mshvildadze and
• André Pichette

Beilstein J. Org. Chem. 2013, 9, 1333–1339, doi:10.3762/bjoc.9.150

• Fondamentales, 555 boul. de l'Université, Chicoutimi (Québec) G7H 2B1, Canada Université de Poitiers, Institut de Chimie IC2MP, UMR-CNRS 7285, 4 rue Michel Brunet, 86022 Poitiers, France 10.3762/bjoc.9.150 Abstract Phytochemical analysis of A. balsamea oleoresin led to the isolation of three new 3,4-seco

• ; lanostane; oleoresin; triterpenoids; Introduction The genus Abies (Pinaceae) comprises 46 species of evergreen conifers [1]. Most of them are found in temperate and boreal regions of the northern hemisphere. The first phytochemical investigation of Abies species was undertaken 75 years ago by Takahashi [2

• tetraterpenoids from the cortical oleoresin of the tree bark, featuring an unprecedented C40 scaffold [6]. Herein, we describe the further phytochemical study of A. balsamea oleoresin, which led to the isolation and structure elucidation of three 3,4-seco-lanostane-type triterpenoids 1–3, one cycloartane-type