Beilstein J. Org. Chem.2014,10, 692–700, doi:10.3762/bjoc.10.62
azomethine ylides, generated in situ from the parent furo[3,2-h]quinoliniums/phenanthroliums, in presence of a copper(II) chloride–phenanthroline catalytic system. The methodology combines general applicability with high yields.
Keywords: copper(II) chloride–phenanthroline; 1,3-dipolar cycloaddition; furo
[3,2-h]quinoliniums; phenanthroliums; pyrrolo[1,2-a]phenanthrolines; pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines; Introduction
The chemistry of the 1,3-dipolar cycloaddition has always been a fascinating undertaking especially when azomethine ylides are involved as the key component
PDF
Graphical Abstract
Scheme 1:
Preparation of maleimide dipolarophiles 4a–c.