Beilstein J. Org. Chem.2010,6, No. 20, doi:10.3762/bjoc.6.20
; glycomimetics; pseudooligosaccharides; spaced sugars; Review
Among the major classes of biomolecules, carbohydrates are characterized by nearly unlimited structural diversity. Monosaccharide units can combine to produce oligosaccharides in a number of permutations that increases rapidly with the number of
years, some reviews on SAAs have summarised the different synthetic methods used to obtain such molecules [12][13][14] as well as their applications to access to a diversity of linear, branched and cyclic pseudooligosaccharides and glycomimetics often referred to as carbopeptoids [13][14][15][16][17
antibiotic against Gram-negative organisms, which contains two highly functionalised aminosugars connected by an urea linkage [61]. While exploring the synthesis of this target molecule, this group established a new method for the stereoselective synthesis of novel β-urea-linked pseudooligosaccharides, which
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Graphical Abstract
Figure 1:
Schematic representation of sugar aminoacids (SAAs) and (pseudo)amide oligosaccharide mimetics.