Microwave-assisted synthesis of 2-substituted 4,5,6,7-tetrahydro-1,3-thiazepines from 4-aminobutanol

• María C. Mollo,
• Natalia B. Kilimciler,
• Juan A. Bisceglia and
• Liliana R. Orelli

Beilstein J. Org. Chem. 2020, 16, 32–38, doi:10.3762/bjoc.16.5

• and affords good to excellent yields of the desired heterocycles in very short reaction times. Keywords: cyclodehydration; medium-size heterocycles; microwaves; PPSE; tetrahydrothiazepines; Introduction Thiazolines (4,5-dihydrothiazoles) are widely studied heterocycles due to their multiple

• 4,5,6,7-tetrahydrothiazepines 4. Supporting Information Supporting Information File 340: Experimental procedures and characterization of new compounds. Acknowledgements We are grateful to Prof. A. Moglioni (Universidad de Buenos Aires. CONICET. Departamento de Farmacología. Facultad de Farmacia y