Beilstein J. Org. Chem.2018,14, 3098–3105, doi:10.3762/bjoc.14.289
phosphoribosyltransferase; catalysis; enzyme; hypoxanthine phosphoribosyltransferase; multi-enzyme cascade; nucleotides; thermophiles; Introduction
Bacterial phosphoribosyltransferases are used in multi-enzymatic cascades that perform nucleotide synthesis de novo [1][2]. Recently, we reported on the possibility of cascade
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Graphical Abstract
Figure 1:
A multi-enzymatic synthesis of modified adenosine -5'-monophosphates.
Beilstein J. Org. Chem.2016,12, 594–607, doi:10.3762/bjoc.12.58
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Taxonomically, the genus Herpetosiphon belongs to the class Chloroflexi within the homonymous phylum. Members of this phylum are metabolically highly diverse, including dehalorespiring anaerobes besides aerobic CO-oxidizing thermophiles, chlorophototrophs and chemoheterotrophs [114][115][116]. Characteristic
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Graphical Abstract
Figure 1:
Natural products isolated from M. xanthus DK1622. DKxanthene-534 (1); myxalamid B (2); myxovirescin...