Stereodiscrimination of guests in chiral organosilica aerogels studied by ESR spectroscopy

• Sebastian Polarz,
• Yasar Krysiak,
• Martin Wessig and
• Florian Kuhlmann

Beilstein J. Nanotechnol. 2025, 16, 2034–2054, doi:10.3762/bjnano.16.140

• probes with surfaces [40]. Mastai and coworkers have used ESR spectroscopy to probe the chirality of crystals [41]. Our group used ESR to investigate the rotational dynamics of paramagnetic spin probes in functionalized, mesoporous organosilica materials [42][43][44][45][46]. Using 3-carboxypropyl (3CP

• diffusion coefficients [44]. In the mentioned studies, we have always used racemic 3CP containing both enantiomers. Because of our previous work on mesoporous organosilica materials containing chiral groups [47][48], particularly amino acid derivatives [49], we became interested in observing the two

• organosilica materials [51][52], also including aerogels [53][54]. The thiol precursor HS-Ph(Si(OiPr)3)2 was established in 2014 for making periodically ordered mesoporous organosilica [55][56], which are characterized by pore sizes in the sub-10 nm range. Because large pore sizes are beneficial for mass

Current status of using adsorbent nanomaterials for removing microplastics from water supply systems: a mini review

• Nguyen Thi Nhan and
• Tran Le Luu

Beilstein J. Nanotechnol. 2025, 16, 1837–1850, doi:10.3762/bjnano.16.127

• ]. Similarly, You et al. reported on MOFs grown on a wood aerogel, ZIF-8@Aerogel, achieving removal efficiencies for polyvinylidene fluoride (PVDF) and PS particles of 91.4% and 85.8%, respectively [62]. Through electrostatic interactions, mesoporous UiO-66-NH2/P123 exhibited exceptional performance, achieving

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• system complexity. Preventive approaches, such as glutenin-genipin cross-linked coatings, effectively reduce plastic shedding under harsh conditions using biodegradable materials; however, they address only source control and lack proven scalability. Imine-functionalized mesoporous magnetic silica

• methods reflect promising directions but require further validation for widespread adoption [127]. Rushdi et al. [128] developed imine-functionalized mesoporous magnetic silica nanoparticles for the simultaneous removal of polystyrene MPs and organic pollutants. The nanoparticles exhibited strong magnetic

Photocatalytic degradation of ofloxacin in water assisted by TiO₂ nanowires on carbon cloth: contributions of H₂O₂ addition and substrate absorbability

• Iram Hussain,
• Lisha Zhang,
• Zhizhen Ye and
• Jin-Ming Wu

Beilstein J. Nanotechnol. 2025, 16, 1567–1579, doi:10.3762/bjnano.16.111

• into the TiO2 lattice. Figure 3b shows the nitrogen adsorption–desorption isotherm of the TiO2 nanowires on carbon cloth at 77 K. The adsorption isotherm exhibits a type-IV profile with an H3 hysteresis loop, indicative of mesoporous structures with slit-like pores. This is further corroborated by the

• pore size distribution, which shows a sharp peak at approximately 4.0 nm, suggesting a uniform pore size. The corresponding pore size distribution curve (Figure 3b, inset) indicates a mesoporous structure. Before calcination, the BET surface area of the titanate on carbon cloth was found to be 3.9 m2·g

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• , making them ideal for targeted drug delivery applications [87]. Mesoporous silica nanoparticles (MSiNPs) are a subclass of SiNPs known for their ordered pore structure, which allows for the encapsulation of large molecules and proteins. Due to their high surface area for drug loading and also to the fact

• clinical translation of metalloantibiotics remains hindered by key challenges, including systemic toxicity, poor stability, and a lack of targeted delivery. In this context, recent advances in nanotechnology-based drug delivery systems, such as liposomes, polymeric nanoparticles, and mesoporous silica

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• ferritin. This property was exploited to design redox and pH dual-responsive ferritin nanoparticles. In drug-loaded mesoporous silica nanoparticles, ferritin was used as a gating material. It covered the pores to prevent drug release and opened only when activated by redox or pH stimuli [98]. Similarly

• ]. In that study, a PEGylated-lipid nanoparticle (PEG-liposome) with a mesoporous silica nanoparticle core (LM) was prepared, and then the nanosystem was coated with CCM (CCM@LM). The biomimetic nanomedicine showed high internalization in a way similar to an enveloped virus. The PEGylation of the inner

• cavity provided subcellular localization of payload in the nucleus subsequent to cellular internalization. The whole nanosystem demonstrated a significant anti-tumor activity. Shao et al. established X-ray-responsive CCM-covered mesoporous organosilica nanoparticles for the controlled release of DOX [135

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

• . Additionally, they can be employed as precursors to produce CaFe2O4 thin films upon calcination. The resulting transparent solution is coated and subjected to calcination/annealing to form mesoporous thin films. The mesoporous films display excellent performance in the oxygen evolution reaction. It would be

• beneficial to extend the findings of this study to explore the nanoarchitectonics of other mesoporous metal oxides in electrocatalytic electrodes. Additionally, there are nanoarchitectonics examples that couple liquid crystal structure control with other functions, such as catalysis. Mavrikakis, Abbott, and

Synthesis of biowaste-derived carbon-dot-mediated silver nanoparticles and the evaluation of electrochemical properties for supercapacitor electrodes

• Navya Kumari Tenkayala,
• Chandan Kumar Maity,
• Md Moniruzzaman and
• Subramani Devaraju

Beilstein J. Nanotechnol. 2025, 16, 933–943, doi:10.3762/bjnano.16.71

• distribution of PG-CDs-AgNPs was responsible for the enhanced surface area [35]. The pore size distribution plot of PG-CDs-AgNPs suggests the mesoporous characteristics (Supporting Information File 1, Figure S1b), which, via the diffusion of electrolyte ions, is highly efficient for electrochemical charge

The impact of tris(pentafluorophenyl)borane hole transport layer doping on interfacial charge extraction and recombination

• Konstantinos Bidinakis and
• Stefan A. L. Weber

Beilstein J. Nanotechnol. 2025, 16, 678–689, doi:10.3762/bjnano.16.52

• the HTL/perovskite interface, whereas negative charges get separated within the mesoporous TiO2. In the traditionally doped cell, we notice that on the HTL side there is a comparable amount of electrons and holes on each side of the junction. On the ETL side, however, there are more positive charges

• deposited a mesoporous TiO2 layer from a (transparent) titania paste solution (Aldrich, 16.67 wt % in ethanol) via spin coating and annealed it (same parameters as in the previous step). After each of these titania deposition steps, we subjected the films to a UV-ozone cleaning step (FHR UVO 150) for 30 min

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

• Shiwani Randhawa,
• Trilok Chand Saini,
• Manik Bathla,
• Rahul Bhardwaj,
• Rubina Dhiman and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

Zeolite materials with Ni and Co: synthesis and catalytic potential in the selective hydrogenation of citral

• Inocente Rodríguez-Iznaga,
• Yailen Costa Marrero,
• Tania Farias Piñeira,
• Céline Fontaine,
• Lexane Paget,
• Beatriz Concepción Rosabal,
• Arbelio Penton Madrigal,
• Vitalii Petranovskii and
• Gwendoline Lafaye

Beilstein J. Nanotechnol. 2025, 16, 520–529, doi:10.3762/bjnano.16.40

• calcium cations leaving the zeolite, as proven by XRD. In line with expectations for a natural zeolite, the studied materials exhibited hybrid type-I/IV adsorption isotherms (see Figure S2 in Supporting Information File 1), indicating the presence of both microporous and mesoporous structures. The

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• , including biochar, metal-organic frameworks (MOFs), functionalized mesoporous silica, porous organic polymers, zeolite, and derivatives of graphene. These substances act as a support for metal oxides and immobilize the catalyst, increase the catalyst surface area, and improve the chemical stability

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• chemical modifications and/or coupling with hydrophilic polymers. TMZ was successfully incorporated in magnetic NPs [36], mesoporous silica NPs [37], and NPs made of silver [38], zinc oxide [39], and gold [40], all of them showing high accumulation in tumor cells and cytotoxic activity in vitro and in vivo

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

• synthesis [32]. The resulting constructions have pore sizes ranging from microporous (<2 nm) to mesoporous (2–50 nm) [30][36]. This simple strategy has led to substantial exploration of various MOFs with different structures and properties for various applications in heterogeneous catalysis, biomedicine

TiO₂ immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

• Marina G. Shelyapina,
• Rosario Isidro Yocupicio-Gaxiola,
• Gleb A. Valkovsky and
• Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

• distance and, hence, the mesopore size, but also the aluminum distribution and acidic properties of the obtained material, which are key parameters for catalysts [5][7][8][9][10]. One widely used component for the synthesis of 2D zeolites is CTAB [5][9][11][12][13]. To prepare mesoporous materials from

• immobilization of TiO2 nanoparticles is of great importance. Many materials are considered as a possible support for immobilization, including porous ceramics [15], glass [16][17], porous carbon materials [18][19], mesoporous silica [20][21][22][23], and zeolites [24][25][26][27]. Recent studies have confirmed

• that direct synthesis of TiO2 in mesoporous silica or zeolites provides strong immobilization of TiO2 nanoparticles through Ti–O–Si bonding [21][22][23]. Previously, we reported the results of the trial synthesis of a new TiO2/2D mordenite nanocomposite [28]. The material was obtained from a composite

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• into clinical practice requires overcoming key challenges, such as ensuring molecular stability, achieving targeted delivery, and minimizing immune activation. Ongoing research is addressing these barriers by advancing RNA delivery systems [77]. For example, mesoporous silica NPs have been utilized to

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

• Benjamin Punz,
• Maja Brajnik,
• Joh Dokler,
• Jaleesia D. Amos,
• Litty Johnson,
• Katie Reilly,
• Anastasios G. Papadiamantis,
• Amaia Green Etxabe,
• Lee Walker,
• Diego S. T. Martinez,
• Steffi Friedrichs,
• Klaus M. Weltring,
• Nazende Günday-Türeli,
• Claus Svendsen,
• Christine Ogilvie Hendren,
• Mark R. Wiesner,
• Martin Himly,
• Iseult Lynch and
• Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

Theoretical study of the electronic and optical properties of a composite formed by the zeolite NaA and a magnetite cluster

• Joel Antúnez-García,
• Roberto Núñez-González,
• Vitalii Petranovskii,
• H’Linh Hmok,
• Armando Reyes-Serrato,
• Fabian N. Murrieta-Rico,
• Mufei Xiao and
• Jonathan Zamora

Beilstein J. Nanotechnol. 2025, 16, 44–53, doi:10.3762/bjnano.16.5

• fewer studies on the cytotoxicity of nanoparticles on zeolite carriers than other mesoporous matrices, most articles report low cytotoxicity of zeolites. Zeolites are classified as “Safe Substances for Food and Feed Additives” by the European Food Safety Authorities [49] and are “Generally Recognized as

Dual-functionalized architecture enables stable and tumor cell-specific SiO₂NPs in complex biological fluids

• Iris Renata Sousa Ribeiro,
• Raquel Frenedoso da Silva,
• Romênia Ramos Domingues,
• Adriana Franco Paes Leme and
• Mateus Borba Cardoso

Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100

• active groups (amino, mercapto, or carboxylic functionalities) to interact with cells, viruses, and bacteria [17][18][20]. Pan et al. [24] developed mesoporous silica nanoparticles (SiO2NPs) covalently attached to (i) poly(oligo(ethylene glycol) monomethyl ether methacrylate) for improved stabilization

• proves to be a successful model that can be extended to other types of NPs, such as degradable mesoporous silica nanoparticles, which are highly porous and can degrade under specific biological conditions, thus preventing inconvenient accumulation in the body. a) Representation of the synthesis steps of

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

• Damai Ria Setyawati,
• Fransiska Christydira Sekaringtyas,
• Riyona Desvy Pratiwi,
• A’liyatur Rosyidah,
• Rohimmahtunnissa Azhar,
• Nunik Gustini,
• Gita Syahputra,
• Idah Rosidah,
• Etik Mardliyati,
• Tarwadi and
• Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

• hepatobiliary clearance in vivo. For example, positively charged mesoporous silica NPs (MSNPs) underwent significant uptake by hepatocytes, while MSNPs with negative charges were rapidly internalized by Kupffer cells in liver sinusoids [33]. The negative charge of the nanocarriers could facilitate efficient

Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• collaborators synthesized mesoporous carbon nanospheres (PMCSs) derived from a MOF precursor, exhibiting dual photodynamic and photothermal characteristics. Utilizing this framework, concentration and temperature at thrombotic sites were elevated significantly upon local irradiation (808 nm laser), resulting in

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

• Le Thi Le,
• Hue Thi Nguyen,
• Liem Thanh Nguyen,
• Huy Quang Tran and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

• , iron oxide, and mesoporous silica nanoparticles) [4]. Additionally, nanocarrier-free systems, such as drug nanocrystals, are also used to improve the delivery of poorly soluble drugs [5][6]. In our previous study, the saturation concentration of BBR in water was 2.0 mg/mL, while BBR nanoparticles

Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems

• Agnes-Valencia Weiss and
• Marc Schneider

Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95

• variable elasticity were prepared by immersing mesoporous silica nanoparticles in carboxybetaine methacrylate (CBMA) and crosslinking those with different amounts of carboxybetaine dimethacrylate (CBMAX). Particles with Young’s moduli between 4.5 and 162 MPa (measured in air) were obtained. By measuring

• -mediated uptake mechanisms, whereas hard NLGs are predominantly internalized via the clathrin-mediated pathway [32]. Another example of the enhanced tumor accumulation of softer nanoparticles is presented by Tao et al. Even though the hyaluronic-acid-modified mesoporous organosilica nanoparticles (MMONs

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• ]. NIR light irradiation for 10 min can yield temperatures up to 61 °C in mesoporous PDA with a photoconversion efficiency of 26.7%. Despite the advantages, many of the polymer nanoparticles show strong photoluminescence and do not withstand long-term light irradiation. To overcome this challenge, hybrid

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• resulted in loss or overcoating of the surface citrate, and, in some cases, agglomeration [10]. Exposure to vitamin C and glutathione led to dissolution-accompanied aggregation of mesoporous silica CeO2 nanoparticles [35]. The shortening of ceria nanorods from 25 to 8 nm after 14 days at 200 °C was