Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• widespread frequency of the disease, high mortality rate, and recurrence after treatment. In addition, biosensors are applied to monitor blood glucose levels in diabetics, identify infections, and track cancer growth [14]. The development of biosensor technologies for cancer screening is crucial and

• biosensors for accurate detection of viruses [25], cancer [15], proteins [36], DNA, glucose [17], and nucleic acids has been strongly developed [37]. On the other hand, specific biomolecule classifications by microbiologists has led to the realization and development of different biosensors, significantly

• biosensor. 4 Summary and future research works FET-based biosensors have been designed and developed to achieve higher performance and improved sensitivity in detecting various types of species, such as viruses, cancer cells, proteins, DNA, glucose, and nucleic acids. The latest emerging 3D and 2D FET-based

Simultaneous electrochemical determination of uric acid and hypoxanthine at a TiO₂/graphene quantum dot-modified electrode

• Vu Ngoc Hoang,
• Dang Thi Ngoc Hoa,
• Nguyen Quang Man,
• Le Vu Truong Son,
• Le Van Thanh Son,
• Vo Thang Nguyen,
• Le Thi Hong Phong,
• Ly Hoang Diem,
• Kieu Chan Ly,
• Ho Sy Thang and
• Dinh Quang Khieu

Beilstein J. Nanotechnol. 2024, 15, 719–732, doi:10.3762/bjnano.15.60

• stability of the (1:4)TiO2/QGDs-GCE (Figure 9d). In order to study the selectivity of the (1:4)TiO2/GQDs-modified electrode, common co-existing substances, namely, NH4Cl, KCl, Na2SO4, NH4NO3, CaCl2, ZnCl2, glucose (GLC), glutamic acid (GLA), urea (URE), ʟ-cysteine (LCY) and xanthine (XTE), have been added

Cholesterol nanoarchaeosomes for alendronate targeted delivery as an anti-endothelial dysfunction agent

• Horacio Emanuel Jerez,
• Yamila Roxana Simioni,
• Kajal Ghosal,
• Maria Jose Morilla and
• Eder Lilia Romero

Beilstein J. Nanotechnol. 2024, 15, 517–534, doi:10.3762/bjnano.15.46

• tebenquichense was grown in basal medium supplemented with yeast extract and glucose in a 25 L custom-made stainless steel bioreactor at 40 °C and harvested after 72 h growth. Total polar archaeolipids (TPA) were extracted from biomass using the Bligh and Dyer method modified for extreme halophiles [74]. Around

• phosphatidylglycerophosphate (PGP-Me), archaeol analog phosphatidylglycerol (PG), (1-O-[α-ᴅ-mannose-(2′-SO3H)-(1′→2′)-α-ᴅ-glucose]-2,3-di-O-phytanyl-sn-glycerol) (S-DGD-5), the cardiolipin bisphosphatidylglycerol (BPG), and the glycocardiolipin (2′-SO3H)-Manp-α-1,2-Glcpa-1–1-[sn-2,3-di-O-phytanylglycerol]-6-[phospho-sn-2,3-di

Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

• Le Hong Tho,
• Bui Xuan Khuyen,
• Ngoc Xuan Dat Mai and
• Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

• (Ag NPs), but the potential of DESs in Ag NP synthesis was neither considered nor studied carefully. In this study, we present a novel strategy to fabricate Ag NPs in a DES (Ag NPs-DES). The DES composed of ᴅ-glucose, urea, and glycerol does not contain any anions to precipitate with Ag+ cations. Our

• the NPs as well as a high aggregation state (Figure 3A). This is because of the high viscosity of the DES, which directly affected the stirring and yielded nonspherical NP shapes. The aggregated Ag NPs are supported by pure DES in which oxygen and hydrogen atoms of ᴅ-glucose, urea, and glycerol tend

• In this study, we have proposed a novel strategy for Ag NP synthesis in a DES composed of ᴅ-glucose, glycerol, and urea. The Ag NPs-DES sample was prepared successfully through chemical reduction, in which DES acts as solvent and shape-controlling agent. Using NFT and SDZ as probe molecules, the SERS

Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• -, peroxidase (POD)-, glucose oxidase (GOx)-, and nitric oxide synthase (NOS)-like activities. More interestingly, both in vitro and in vivo experiments demonstrated that the nanocomposite spray can be activated by the diabetic foot ulcer microenvironment to accelerate diabetic wound healing through decreasing

• inflammation, lowering blood glucose, relieving hypoxia, promoting angiogenesis, and eliminating pathogenic bacteria. Other in vivo experiments demonstrated that mice treated with silver-based nanocomposites showed significantly higher (p < 0.001) wound contraction compared to saline solution (negative control

Multiscale modelling of biomolecular corona formation on metallic surfaces

• Parinaz Mosaddeghi Amini,
• Ian Rouse,
• Julia Subbotina and
• Vladimir Lobaskin

Beilstein J. Nanotechnol. 2024, 15, 215–229, doi:10.3762/bjnano.15.21

• (−21.70kBT to 2.86kBT) [2]. We also show the PMF for glucose with aluminum surfaces, used as the basis for a model of lactose, a sugar highly present in milk, as discussed later, computed using the PMFPredictor software in Figure 6 [38]. Protein–NP interactions To further understand the adsorption energy and

• the chosen compounds. It includes their UniProt IDs, molecular weights, charges, and the number of AAs in each protein. The charge data was determined through the PROPKA method [42][43] at a pH of 7.0. We model the lactose molecule as a pair of glucose beads; it does not possess a UniProt ID or a

• high concentration in milk. We model the lactose molecule as a pair of glucose beads separated by a distance determined by the equilibrium structure of lactose. Although this is not completely rigorous, it demonstrates how the UnitedAtom software can be adapted to model larger molecules other than

Study of the reusability and stability of nylon nanofibres as an antibody immobilisation surface

• Inés Peraile,
• Matilde Gil-García,
• Laura González-López,
• Nushin A. Dabbagh-Escalante,
• Juan C. Cabria-Ramos and
• Paloma Lorenzo-Lozano

Beilstein J. Nanotechnol. 2024, 15, 83–94, doi:10.3762/bjnano.15.8

• clinical applications. Immunoassay devices have been used not only for the detection of bacteria and viruses [7], but also for the measurement of drugs [8] and hormones [9], or for the determination of glucose in urine [10]. The specificity of antigen–antibody binding and how the antibody is attached to

Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems

• Agnes-Valencia Weiss and
• Marc Schneider

Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95

• (e.g., Caco-2 monolayers, or HT29-MTX-E12 cells, or an in vitro model of a rat everted intestinal sac) the Papp values are higher for NPs with higher Young’s moduli [40]. The blood glucose levels of diabetic rats treated by gavage with insulin or insulin-loaded NPs of different Young’s moduli were

• measured. The results show that the plasma insulin levels where higher for harder NPs, and this correlated with blood glucose reduction. Furthermore, 3 h after application, they found a larger amount of hard NPs in the intestinal villi [40]. All studies support our hypothesis that mechanical properties of

Ni, Co, Zn, and Cu metal-organic framework-based nanomaterials for electrochemical reduction of CO₂: A review

• Ha Huu Do and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 904–911, doi:10.3762/bjnano.14.74

• from metal ions and organic linkers, and have been identified as prospective materials for CO2RR [21]. Therefore, a multitude of MOFs structures have been explored in experimental studies [22][23], exhibiting diverse applications such as gas storage [24], electrocatalysis [25][26][27], glucose sensing

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• glucose oxidase, suggesting the use of this phenomenon as a colorimetric sensor for bioanalysis [49]. This color transition is an important observation since nanoceria degradation will likely result in the change in oxidation state of surface cerium ions from Ce4+ to Ce3+. Results and Discussion Nanoceria

A graphene quantum dots–glassy carbon electrode-based electrochemical sensor for monitoring malathion

• Sanju Tanwar,
• Aditi Sharma and
• Dhirendra Mathur

Beilstein J. Nanotechnol. 2023, 14, 701–710, doi:10.3762/bjnano.14.56

• hydrothermal process with glucose as a precursor undergoing carbonization. Different spectroscopic techniques were used to analyze the optical characteristics of GQDs, including UV–visible, photoluminescence, FTIR, and Raman spectroscopy. Atomic force microscopy, transmission electron microscopy, and X-ray

• organophosphate pesticide malathion. Graphene quantum dots were synthesized hydrothermally using glucose as precursor. The glassy carbon electrode that served as working electrode in the electrochemical cell was modified with graphene quantum dots by drop casting. To evaluate the modified electrode’s oxidation

• were found to be effective sensing platforms for the electrochemical detection of organophosphate pesticides, particularly malathion. Experimental Materials Glucose (C6H12O6), conc. sulfuric acid (98% H2SO4), potassium hexacyanoferrate(III) (C6FeK3N6), and potassium chloride (KCl) were obtained from

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

Microneedle patches – the future of drug delivery and vaccination?

• Zahra Faraji Rad,
• Philip D. Prewett and
• Graham J. Davies

Beilstein J. Nanotechnol. 2023, 14, 494–495, doi:10.3762/bjnano.14.40

• blood for diagnostic tests. Other tests, such as blood glucose monitoring in diabetics [1], release blood by a pinprick from the capillaries immediately beneath the skin. Microneedles (MNs), typically less than 1 mm long, are a late 20th century development with significant promise for the above

Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities

• Akif Hakan Kurt,
• Elif Berna Olutas,
• Fatma Avcioglu,
• Hamza Karakuş,
• Mehmet Ali Sungur,
• Cansu Kara Oztabag and
• Muhammet Yıldırım

Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31

• /v) penicillin/streptomycin (Gibco; Thermo Scientific, USA) containing high-glucose DMEM (Gibco; Thermo Scientific, USA) in an incubator at 37 °C with 5% CO2 pressure. Cell viability assay (XTT) The cells were planted at approximately 10,000/100 µL per well in 96-well plates. To reveal the dose–time

Cyclodextrins as eminent constituents in nanoarchitectonics for drug delivery systems

• Makoto Komiyama

Beilstein J. Nanotechnol. 2023, 14, 218–232, doi:10.3762/bjnano.14.21

• construct a variety of nanostructures. The cylindrical structures are stabilized by rings of intramolecular hydrogen bonds between adjacent glucose units. The internal diameters of the cavities of α-, β-, and γ-CyDs (composed of six, seven, and eight ᴅ-glucose units) are about 4.5–6, 6–8, and 8–9.5 Å

Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine

• Zoran M. Marković,
• Milica D. Budimir,
• Martin Danko,
• Dušan D. Milivojević,
• Pavel Kubat,
• Danica Z. Zmejkoski,
• Vladimir B. Pavlović,
• Marija M. Mojsin,
• Milena J. Stevanović and
• Biljana M. Todorović Marković

Beilstein J. Nanotechnol. 2023, 14, 165–174, doi:10.3762/bjnano.14.17

• -glucose Dulbecco's Modified Eagle's Medium (DMEM) supplemented with 10% fetal bovine serum, non-essential amino acids, and penicillin/streptomycin solution (10,000 units penicillin and 10 mg/mL streptomycin) (all from Thermo Fisher Scientific). Cells were maintained in a humidified incubator at 37 °C with

Antimicrobial and mechanical properties of functionalized textile by nanoarchitectured photoinduced Ag@polymer coating

• Jessica Plé,
• Marine Dabert,
• Helene Lecoq,
• Sophie Hellé,
• Lydie Ploux and
• Lavinia Balan

Beilstein J. Nanotechnol. 2023, 14, 95–109, doi:10.3762/bjnano.14.11

• composed of 0.1 M KH2PO4, 20 wt % (NH4)2SO4, 0.1 wt % FeSO4, 20 wt % MgSO4, 6 M KOH, 0.05 wt % vitamin B1 and 10 wt % glucose; pH adjusted at 6.8; all products purchased by Sigma-Aldrich) were prepared [41], before undergoing an overnight incubation at 30 °C and 37 °C, respectively. The as-prepared pre

In search of cytotoxic selectivity on cancer cells with biogenically synthesized Ag/AgCl nanoparticles

• Mitzi J. Ramírez-Hernández,
• Mario Valera-Zaragoza,
• Omar Viñas-Bravo,
• Ariana A. Huerta-Heredia,
• Miguel A. Peña-Rico,
• Erick A. Juarez-Arellano,
• David Paniagua-Vega,
• Eduardo Ramírez-Vargas and
• Saúl Sánchez-Valdes

Beilstein J. Nanotechnol. 2022, 13, 1505–1519, doi:10.3762/bjnano.13.124

• MCF-7 human breast cell line was obtained from the American Type Culture Collection (ATCC®). This cell line was at passage 4 when used in the study and was routinely cultured on monolayers at 80% confluence in Dulbecco's modified Eagle's high glucose medium (DMEM), supplemented with 10% of fetal

Structural studies and selected physical investigations of LiCoO₂ obtained by combustion synthesis

• Monika Michalska,
• Paweł Ławniczak,
• Tomasz Strachowski,
• Adam Ostrowski and
• Waldemar Bednarski

Beilstein J. Nanotechnol. 2022, 13, 1473–1482, doi:10.3762/bjnano.13.121

• powders 25.408 g of high-purity cobalt(II) acetate tetrahydrate (C4H6O4Co·4H2O, reagent grade), 10.408 g of lithium acetate dihydrate (C2H3O2Li·2H2O, purum p.a., crystallized, 97.0% (NT)) and 20 g of ᴅ-(+)-glucose (C6H12O6, ≥99.5% (GC), Sigma-Aldrich) were used to synthesize LiCoO2 nanocrystalline powders

• . Cobalt and lithium acetate salts were dissolved separately in small amounts of deionized water. Then, the solutions were mixed together and a solution of ᴅ-(+)-glucose was added. The prepared solutions were then evaporated until a gel was obtained. The resulting gel precursor was heated from 450 to 900

LED-light-activated photocatalytic performance of metal-free carbon-modified hexagonal boron nitride towards degradation of methylene blue and phenol

• Nirmalendu S. Mishra and
• Pichiah Saravanan

Beilstein J. Nanotechnol. 2022, 13, 1380–1392, doi:10.3762/bjnano.13.114

• light photocatalyst. Materials and Methods Chemicals required Boric acid (H3BO3), melamine, glucose, hexagonal boron nitride nanopowder (BET surface area: 19 m−2 g−1), MB, and phenol were purchased from Alfa Aesar and TCI chemicals. All the purchased chemicals were high purity analytical grade reagents

• and utilized without any further purification. Synthesis procedure The modified HBN was synthesized through a solid-state reaction approach with various modifications to the process described in Wang et al. [17]. An equimolar mix (0.1 M) of melamine, boric acid, and glucose was finely grounded in an

• agate mortar pestle to form a uniform white mixture. The bandgap could be regulated by the amount of carbon substituted into the lattice sites, with higher concentration of C atoms leading to better light harvesting and electronic properties [17][18]. Thus, the amount of glucose utilized for this study

Recent trends in Bi-based nanomaterials: challenges, fabrication, enhancement techniques, and environmental applications

• Vishal Dutta,
• Ankush Chauhan,
• Ritesh Verma,
• C. Gopalkrishnan and
• Van-Huy Nguyen

Beilstein J. Nanotechnol. 2022, 13, 1316–1336, doi:10.3762/bjnano.13.109

• of Bi2MoO6, they employed glucose as a reducing agent. To test the photocatalytic activity, they exposed the as-prepared materials to simulated solar irradiation and measured the degradation efficiency of RhB (7.321%), MB (92.98%), and Cr(VI) (70.54%). The highest hydrogen generation rate was 173.41

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• QCM electrodes for chiral sensing. Cyclodextrin derivatives. Cyclodextrins (CDs) are a class of oligomers composed of glucose units. They possess hollow truncated cones with a lipophilic inner cavity and a hydrophilic edge. The hydroxy groups at the edge can undergo different chemical reactions, which

• allows for modifications by a variety of functional substituents [60][61][62]. Therefore, CDs and derivatives are the most used host superstructures to adapt the selection of various chiral guests. The chiral recognition sites of CDs may arise from their glucose chiral units and functionalities on the

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• described the reaction mechanism, which involves hydrolyzation of starch to form glucose, and then glucose is condensed to form CDs by ring-closure condensation. These CDs have been effectively used in bioimaging of cervical cancer cells as a suitable PL probe [124]. Wen et al. have created an incredibly

Interaction between honeybee mandibles and propolis

• Leonie Saccardi,
• Franz Brümmer,
• Jonas Schiebl,
• Oliver Schwarz,
• Alexander Kovalev and
• Stanislav Gorb

Beilstein J. Nanotechnol. 2022, 13, 958–974, doi:10.3762/bjnano.13.84

• that due to gland development, only older stingless bees are able to handle propolis [20]. Mandibular glands of honeybees have been found to have a high potential to produce lipids [41]. Glucose oxidase, produced in the mandibular glands, has been found in propolis [42][43]. Which could be an indicator

A non-enzymatic electrochemical hydrogen peroxide sensor based on copper oxide nanostructures

• Irena Mihailova,
• Vjaceslavs Gerbreders,
• Marina Krasovska,
• Eriks Sledevskis,
• Valdis Mizers,
• Andrejs Bulanovs and
• Andrejs Ogurcovs

Beilstein J. Nanotechnol. 2022, 13, 424–436, doi:10.3762/bjnano.13.35

• interfering substances, that is, ascorbic acid, uric acid, dopamine, NaCl, glucose, and acetaminophen, do not affect the electrochemical response. The real milk sample test showed a high recovery rate (more than 95%). According to the obtained results, this sensor is suitable for practical use for the

• ), uric acid (C5H4N4O3, CAS number: 69-93-2), dopamine hydrochloride ((HO)2C6H3CH2CH2NH2HCl, CAS number: 62-31-7), glucose (C6H12O6, CAS number: 50-99-7), acetaminophen (CH3CONHC6H4OH, CAS number: 103-90-2), and sodium chloride (NaCl, CAS number: 7647-14-5) were purchased from Sigma-Aldrich. All reagents

• NaOH was used. The experiment was started at 0 µM concentration of H2O2, then every 60 s either H2O2 or an interfering substance at a concentration of 100 µM was added to the solution, in the following order: H2O2, ascorbic acid, uric acid, dopamine, NaCl, glucose, and acetaminophen. Then, the whole