DNA aptamer selection and construction of an aptasensor based on graphene FETs for Zika virus NS1 protein detection

• Nathalie B. F. Almeida,
• Thiago A. S. L. Sousa,
• Viviane C. F. Santos,
• Camila M. S. Lacerda,
• Thais G. Silva,
• Rafaella F. Q. Grenfell,
• Flavio Plentz and
• Antero S. R. Andrade

Beilstein J. Nanotechnol. 2022, 13, 873–881, doi:10.3762/bjnano.13.78

• immobilization on graphene via π–π stacking [34]. The qualitative confirmation of aptamer immobilization on graphene is illustrated in Figure 4a. For a representative device, Figure 4a exhibits curves of graphene resistance (RSD) as a function of the gate voltage (VG) before (black line) and after (red line

• pyrene moiety of ZIKV60 and the π orbitals of graphene [38][39]. Consequently, the electron transfer to graphene after functionalization reveals a factual immobilization of ZIKV60 aptamers on its surface. Similar results were obtained for four additional graphene devices. See Figure S4 (Supporting

A nonenzymatic reduced graphene oxide-based nanosensor for parathion

• Sarani Sen,
• Anurag Roy,
• Ambarish Sanyal and
• Parukuttyamma Sujatha Devi

Beilstein J. Nanotechnol. 2022, 13, 730–744, doi:10.3762/bjnano.13.65

• agricultural samples using enzyme-based nanosensors is challenging. The stability of bionanosensors also extensively depends on the viability of the corresponding biomolecule during the matrix immobilization course [9]. The main drawbacks of using bionanosensors for the selective detection of OP in actual

A non-enzymatic electrochemical hydrogen peroxide sensor based on copper oxide nanostructures

• Irena Mihailova,
• Vjaceslavs Gerbreders,
• Marina Krasovska,
• Eriks Sledevskis,
• Valdis Mizers,
• Andrejs Bulanovs and
• Andrejs Ogurcovs

Beilstein J. Nanotechnol. 2022, 13, 424–436, doi:10.3762/bjnano.13.35

• electrodes without additional treatments such as surface modification or enzyme immobilization. This article describes the process of obtaining wire electrodes with nanostructured CuO coatings by a one-step chemical hydrothermal oxidation method and their application in electrochemical measurements for the

Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis

• Zahra Nabizadeh,
• Mahmoud Nasrollahzadeh,
• Hamed Daemi,
• Mohamadreza Baghaban Eslaminejad,
• Ali Akbar Shabani,
• Mehdi Dadashpour,
• Majid Mirmohammadkhani and
• Davood Nasrabadi

Beilstein J. Nanotechnol. 2022, 13, 363–389, doi:10.3762/bjnano.13.31

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

• prevention of agglomeration [102]. Titania nanostructures are capable of loading molecules of various sizes, charges, and solubilities. The immobilization of drugs and their release profile is affected by the size and surface charge distribution of the drug molecule. It has been stated that for the long-term

A comprehensive review on electrospun nanohybrid membranes for wastewater treatment

• Senuri Kumarage,
• Imalka Munaweera and
• Nilwala Kottegoda

Beilstein J. Nanotechnol. 2022, 13, 137–159, doi:10.3762/bjnano.13.10

• regulation of parameters has made the electrospun nanofibers find its applications in various areas such as the health sector, food, energy and textile industries, and environmental remediation. Electrospun nanohybrids (ENHs) produced by immobilization of function-specific nanoparticles or mixtures of

A photonic crystal material for the online detection of nonpolar hydrocarbon vapors

• Evgenii S. Bolshakov,
• Aleksander V. Ivanov,
• Andrei A. Kozlov,
• Anton S. Aksenov,
• Elena V. Isanbaeva,
• Sergei E. Kushnir,
• Aleksei D. Yapryntsev,
• Aleksander E. Baranchikov and
• Yury A. Zolotov

Beilstein J. Nanotechnol. 2022, 13, 127–136, doi:10.3762/bjnano.13.9

• ) formation of a sensitive polymer matrix, (b) impregnation of the reagent, (c) immobilization of the reagent and (d) preparation of the sensor elements from molecularly imprinted polymers. Organic solvents are usually detected by using polymer matrix sensors (Table 1) through matrix interaction [7][8][9][15

• ][16]. The impregnation and immobilization methods are rather close; they are used for the determination of inorganic ions (Cu2+, Pb2+, Hg2+, Ni2+ and Cd2+) [2][11][17][18][19] and organic molecules of simple and complex structure (glucose, organophosphates, urea, creatinine, ciprofloxacin and sarin

Theranostic potential of self-luminescent branched polyethyleneimine-coated superparamagnetic iron oxide nanoparticles

• Rouhollah Khodadust,
• Ozlem Unal and
• Havva Yagci Acar

Beilstein J. Nanotechnol. 2022, 13, 82–95, doi:10.3762/bjnano.13.6

• amines during the synthesis of SPION@bPEI is responsible for the enhanced bPEI luminescence. It is further enhanced with the immobilization of bPEI on SPION crystals and post-synthetic acidification of the particles, which also increased the rigidity. These nanoparticles have a small hydrodynamic size

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

Progress and innovation of nanostructured sulfur cathodes and metal-free anodes for room-temperature Na–S batteries

• Marina Tabuyo-Martínez,
• Bernd Wicklein and
• Pilar Aranda

Beilstein J. Nanotechnol. 2021, 12, 995–1020, doi:10.3762/bjnano.12.75

• oxygen doping have proven to enhance the immobilization of sodium polysulfides leading to an advancement in battery performance [31][32]. Adsorption and trapping of polysulfides are achieved through strong interactions between the sodium atoms in sodium polysulfides and the nitrogen and oxygen atoms. The

• carbon (HSMC). The resulting electrode exhibited a Coulombic efficiency of 100% and a capacity of 610 mAh·g−1 after 110 cycles at 0.03C. This improved cycling stability was attributed to the conductivity enhancement imparted by copper, the sulfur immobilization due to strong copper–polysulfide

• shuttle effect. Zhang et al. [47] studied iron, copper, and nickel nanoclusters (ca 1.2 nm) loaded onto hollow carbon nanospheres. On the one hand, the chemical coupling between nanocluster and sulfur assists in sulfur immobilization and enhances conductivity and reactivity. On the other hand, the

Modification of a SERS-active Ag surface to promote adsorption of charged analytes: effect of Cu²⁺ ions

• Bahdan V. Ranishenka,
• Andrei Yu. Panarin,
• Irina A. Chelnokova,
• Sergei N. Terekhov,
• Peter Mojzes and
• Vadim V. Shmanai

Beilstein J. Nanotechnol. 2021, 12, 902–912, doi:10.3762/bjnano.12.67

• the electrostatic interaction between analyte molecules and silver nanoparticles (Ag NPs) on the intensity of surface-enhanced Raman scattering (SERS). For this, we fabricated nanostructured plasmonic films by immobilization of Ag NPs on glass plates and functionalized them by a set of differently

• the analyte leads to a good SERS signal. Results and Discussion Characterization of silver nanostructures We synthesized Ag NPs with a size appropriate for SERS investigations (30–35 nm) with a relatively high NP concentration (32 µg/mL) sufficient for good immobilization. Size and shape of the NPs

• were analyzed from SEM and TEM images. To achieve a better resolution during SEM, we utilized a conductive silicon support and excluded the metal coating of the sample; Ag NPs were placed on the silicon surface by adsorptive immobilization to avoid aggregation during solvent evaporation. Figure 1 shows

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• epidermis. Immobilization is both physical, due to the low diffusivity of the particles, and chemical, since thiol-exchange reactions occur with Ag+ but not with AgNPs. This fact explains why AgNPs are not responsible for causing argyria or argyrosis [1][11]. It is well known that the strong interaction of

TiO_x/Pt₃Ti(111) surface-directed formation of electronically responsive supramolecular assemblies of tungsten oxide clusters

• Marco Moors,
• Yun An,
• Agnieszka Kuc and
• Kirill Yu. Monakhov

Beilstein J. Nanotechnol. 2021, 12, 203–212, doi:10.3762/bjnano.12.16

• Dresden-Rossendorf, Department of Reactive Transport, Institute of Resource Ecology, Permoserstraße 15, 04318 Leipzig, Germany 10.3762/bjnano.12.16 Abstract Highly ordered titanium oxide films grown on a Pt3Ti(111) alloy surface were utilized for the controlled immobilization and tip-induced electric

Fusion of purple membranes triggered by immobilization on carbon nanomembranes

• René Riedel,
• Natalie Frese,
• Fang Yang,
• Martin Wortmann,
• Raphael Dalpke,
• Daniel Rhinow,
• Norbert Hampp and
• Armin Gölzhäuser

Beilstein J. Nanotechnol. 2021, 12, 93–101, doi:10.3762/bjnano.12.8

• surface coverage and to close gaps between the PM patches. This procedure for the immobilization of oriented dense PM facilitates the spontaneous fusion of individual PM patches, forming larger membrane areas. This is, to our knowledge, the very first procedure described to induce the oriented fusion of

• is essentially one monolayer of PM patches on the CNM, but the coverage is less than 100% and in some regions irregularly arranged PM patches overlap. Immobilization of PM was achieved by complex formation of nickel(II) nitrilotriacetic acid (Ni-NTA), coupled to the NBPT CNM, with the C-terminal

• capacitor plate distance of 2 mm. Immobilization of the resulting PM quasi-monolayer has been achieved by the complex formation through Ni-NTA between the functionalized CNM and the C-terminal His-tag of PM. Interconnected regions of c-His PM of more than 15 µm in diameter have thus been obtained. We are

Bio-imaging with the helium-ion microscope: A review

• Matthias Schmidt,
• James M. Byrne and
• Ilari J. Maasilta

Beilstein J. Nanotechnol. 2021, 12, 1–23, doi:10.3762/bjnano.12.1

• routinely applied drying methods is given. (I) Freeze drying: Samples are frozen (e.g., using a plunge or high-pressure freezer) and then dried under vacuum. Uryu et al. suggested a pathway which includes plunge freezing for instantaneous immobilization followed by freeze drying in a cold nitrogen gas and

Electrokinetic characterization of synthetic protein nanoparticles

• Daniel F. Quevedo,
• Cody J. Lentz,
• Adriana Coll de Peña,
• Yazmin Hernandez,
• Nahal Habibi,
• Rikako Miki,
• Joerg Lahann and
• Blanca H. Lapizco-Encinas

Beilstein J. Nanotechnol. 2020, 11, 1556–1567, doi:10.3762/bjnano.11.138

• immobilization to industrial processes [1][2]. The development of nanoparticles composed primarily of proteins has been an emerging sector in nanotechnology [3]. Proteins have multiple desirable characteristics that enable them to be used as the main component of nanoparticles. Proteins are biodegradable

One-step synthesis of carbon-supported electrocatalysts

• Sebastian Tigges,
• Nicolas Wöhrl,
• Ivan Radev,
• Ulrich Hagemann,
• Markus Heidelmann,
• Thai Binh Nguyen,
• Stanislav Gorelkov,
• Stephan Schulz and
• Axel Lorke

Beilstein J. Nanotechnol. 2020, 11, 1419–1431, doi:10.3762/bjnano.11.126

• , and Pt-NPs with a mean particle diameter less than 3 nm and a narrow particle size distribution (PSD) with a geometric standard deviation of 1.24–1.3 can be achieved. Furthermore, the NP immobilization within the carbon support significantly improves the long-term stability of the catalyst, as shown

Evaluation of click chemistry microarrays for immunosensing of alpha-fetoprotein (AFP)

• Seyed Mohammad Mahdi Dadfar,
• Sylwia Sekula-Neuner,
• Vanessa Trouillet,
• Hui-Yu Liu,
• Ravi Kumar,
• Annie K. Powell and
• Michael Hirtz

Beilstein J. Nanotechnol. 2019, 10, 2505–2515, doi:10.3762/bjnano.10.241

• successful implementation and a thorough comparison of their properties. Characterization of the surfaces by XPS and AFM All steps of the immobilization reactions were monitored by X-ray photoelectron spectroscopy (XPS) to validate the expected chemical reactions taking place (Figure 2). The

• confounding factors in the evaluation of surface binding. Comparison of the immobilization routes for the sandwich application The performance of the different types of biotinylated surfaces was probed by addition of a biotin–streptavidin–biotin sandwich structure for antibody immobilization (Figure 3). To

• subsequent click chemistry immobilization of biotin. In the present setup, the functionalization by thiol–silane with subsequent biotin immobilization by biotin–maleimide as well as the functionalization by epoxy–silane with subsequent biotin immobilization by biotin–amine yielded the best performance of the

Small protein sequences can induce cellular uptake of complex nanohybrids

• Jan-Philip Merkl,
• Malak Safi,
• Christian Schmidtke,
• Fadi Aldeek,
• Johannes Ostermann,
• Tatiana Domitrovic,
• Sebastian Gärtner,
• John E. Johnson,
• Horst Weller and
• Hedi Mattoussi

Beilstein J. Nanotechnol. 2019, 10, 2477–2482, doi:10.3762/bjnano.10.238

• -functionalized polyisoprene-block-polyethylene oxide (PI-b-PEO-NH2). The lateral amine groups allowed attachments to AuNPs, which then served for the immobilization of a few His6-MBP-γ, as schematically shown in Figure 1A. To demonstrate the potential utility of this nanohybrid system in biology, colloidal

Targeted therapeutic effect against the breast cancer cell line MCF-7 with a CuFe₂O₄/silica/cisplatin nanocomposite formulation

• B. Rabindran Jermy,
• Vijaya Ravinayagam,
• Widyan A. Alamoudi,
• Dana Almohazey,
• Hatim Dafalla,
• Lina Hussain Allehaibi,
• Abdulhadi Baykal,
• Muhammet S. Toprak and
• Thirunavukkarasu Somanathan

Beilstein J. Nanotechnol. 2019, 10, 2217–2228, doi:10.3762/bjnano.10.214

• -shell support thickness of about 50 nm was reported with a high ferrite loading capacity of about 30–50 wt % with particle diameters between 9 and 17 nm (at the external carbon layer). Such a magnetic nanoformulation was found to be useful for enzyme lysozyme immobilization. The magnetic properties of

Review of advanced sensor devices employing nanoarchitectonics concepts

• Katsuhiko Ariga,
• Tatsuyuki Makita,
• Masato Ito,
• Taizo Mori,
• Shun Watanabe and
• Jun Takeya

Beilstein J. Nanotechnol. 2019, 10, 2014–2030, doi:10.3762/bjnano.10.198

• formaldehyde over the other volatile organic compounds. This nanoarchitectonic strategy using molecular sieving effects of nanoporous frameworks can be applied to other targets of selected molecular size. Ultrathin films The immobilization of functional materials with ultrathin films such as self-assembled

• an organic field-effect transistor, which was used for the sensitive detection of small organic acid molecules, such as citric acid [142]. Hattori and co-workers fabricated an ATP/ADP sensitive image sensor by immobilization of apyrase as a self-assembled monolayer on a 128 × 128 pixel array

Layered double hydroxide/sepiolite hybrid nanoarchitectures for the controlled release of herbicides

• Ediana Paula Rebitski,
• Margarita Darder and
• Pilar Aranda

Beilstein J. Nanotechnol. 2019, 10, 1679–1690, doi:10.3762/bjnano.10.163

• the above mentioned applications, in particular, for uses as host substrate in the immobilization of active species (e.g., drugs, pesticides, and DNA) for controlled-delivery applications [27][28][29]. LDH have been also used in the construction of different types of nanoarchitectonic materials. The

Materials nanoarchitectonics at two-dimensional liquid interfaces

• Katsuhiko Ariga,
• Michio Matsumoto,
• Taizo Mori and
• Lok Kumar Shrestha

Beilstein J. Nanotechnol. 2019, 10, 1559–1587, doi:10.3762/bjnano.10.153

• systems fabricated with low-dimensional materials are actively investigated. For example, Lvov and co-workers reported the immobilization of small functional materials such as metal clusters and metal catalysts within one-dimensional halloysite clay nanotubes to make them work under appropriate protection

Multicomponent bionanocomposites based on clay nanoarchitectures for electrochemical devices

• Giulia Lo Dico,
• Bernd Wicklein,
• Lorenzo Lisuzzo,
• Giuseppe Lazzara,
• Pilar Aranda and
• Eduardo Ruiz-Hitzky

Beilstein J. Nanotechnol. 2019, 10, 1303–1315, doi:10.3762/bjnano.10.129

• glucose oxidase (GOx) into the lumen of HNTs has been chosen here as an example for the immobilization of bioactive species, which can be crucial to design (bio)electrochemical devices with high performance and long life-time. The SEP, GNP, and MWCNT components are also expected to behave as polymer

• material in aqueous media. Moreover, the successful incorporation of HNTs as nanoreactor prompted the use of these bionanocomposite materials in bioelectrocatalysis applications (see below). Immobilization of glucose oxidase in the lumen of HNTs The developed multicomponent bionanocomposites were used for

• the immobilization of the enzyme glucose oxidase in the search of multifunctional properties of interest in bioelectrochemical applications. GOx was chosen as a prototypic bioactive component because of its properties and compatibility with HNTs, i.e., an appropriate size (5.4 nm) as well as an

Photoactive nanoarchitectures based on clays incorporating TiO₂ and ZnO nanoparticles

• Eduardo Ruiz-Hitzky,
• Pilar Aranda,
• Marwa Akkari,
• Nithima Khaorapapong and
• Makoto Ogawa

Beilstein J. Nanotechnol. 2019, 10, 1140–1156, doi:10.3762/bjnano.10.114

• of functional nanoarchitectures. Within this scope, clays can be of special relevance in the production of photoactive materials as they offer an advantageous way for the stabilization and immobilization of diverse metal-oxide nanoparticles. The controlled assembly under mild conditions of titanium

• ; nanoarchitectures; photocatalysts; titanium dioxide; zinc dioxide; Review Introduction: immobilization of nanoscale TiO2 and ZnO on clay minerals Nanoarchitectonics is a term coined by Japan's National Institute for Materials Science (NIMS), which refers to the nanoscale design of complex materials through a deep

• aluminol groups (Al–OH) with a structural arrangement similar to that of the kaolinite 1:1 phyllosilicate (Figure 1D). These groups able to interact with diverse compounds entering the cavities, facilitating their immobilization [76][77][78][79]. The morphology of HNTs yields some advantages with regard to