Advances of aptamers in esophageal cancer diagnosis, treatment and drug delivery

• Yang Fei,
• Hui Xu,
• Chunwei Zhang,
• Jingjing Wang and
• Yong Jin

Beilstein J. Nanotechnol. 2025, 16, 1734–1750, doi:10.3762/bjnano.16.121

• a single biometric element to directly analyze biomarkers [45][46], while dual-system biosensors combine two antibodies and/or aptamers [47] into a better composite material to improve the specificity and sensitivity of the sensor. Figure 3 is a schematic diagram of a gold nanoparticle aptasensor

Beyond the bilayer: multilayered hygroscopic actuation in pine cone scales

• Kim Ulrich,
• Max David Mylo,
• Tom Masselter,
• Fabian Scheckenbach,
• Sophia Fischerbauer,
• Martin Nopens,
• Silja Flenner,
• Imke Greving,
• Linnea Hesse and
• Thomas Speck

Beilstein J. Nanotechnol. 2025, 16, 1695–1710, doi:10.3762/bjnano.16.119

• the bending of bilayer geometries due to an overestimated contribution of sclerenchyma fiber stiffness. Geometries with discrete fibers embedded in a brown tissue matrix more accurately reproduced the bending angles observed in experiments. This highlights the importance of the chosen material

• due to the unknown sorption history of the sample [31]. We then divided the total amount of separated tissue material equally into five sample dishes each. The gravimetric water uptake of the extracted samples was then measured using a sorption test system (SPSx-1µ-High-Load, ProUmid, Germany) and a

• X- and Y-directions (spanning the cross section of each model), the mean value of the two measured values was used, while the Z-value (from the basal to the apical end of the models) was derived directly. The same coefficients were used in all simulations. A linear elastic material model was applied

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

• representative studies at MAX IV, including investigations of single-atom catalysts, confined catalysis, time-resolved catalysis, atomic layer deposition, and electrochemical interfaces, showcasing the role of APXPS in advancing material and surface science. Keywords: 2D materials; atomic layer deposition

• material interfaces under more realistic conditions, which is a critical advancement in material research, gaining increasing popularity across various fields. APXPS is crucial for studying dynamic processes in catalysis, environmental science, and energy materials, where reactions typically occur at or

• fields of, among others, catalysis research, material characterization, and thin film deposition, utilizing dedicated cells. HIPPIE, on the 3 GeV ring, covers a wider photon energy range than SPECIES (250 to 2500 eV), also with variable polarization [10]. It has two branches, each with its own

Prospects of nanotechnology and natural products for cancer and immunotherapy

• Jan Filipe Andrade Santos,
• Marcela Bernardes Brasileiro,
• Pamela Danielle Cavalcante Barreto,
• Ligiane Aranha Rocha and
• José Adão Carvalho Nascimento Júnior

Beilstein J. Nanotechnol. 2025, 16, 1644–1667, doi:10.3762/bjnano.16.116

• spontaneously from the organization of active or natural compounds, without the presence of a carrier material or excipients. Their stability is due to the presence of intermolecular interactions, such as electrostatic forces, hydrogen bonding, π–π stacking, and hydrophobic interactions [104][105]. Among the

• nanoparticles are semiconductor structures smaller than typical nanoparticles, ranging from 2 to 10 nm in size. They are composed of heavy metal or inorganic material and exhibit fluorescent activity, making them commonly used for pharmaceutical applications [153][154]. The technology’s composition is

Venom-loaded cationic-functionalized poly(lactic acid) nanoparticles for serum production against Tityus serrulatus scorpion

• Philippe de Castro Mesquita,
• Karla Samara Rocha Soares,
• Manoela Torres-Rêgo,
• Emanuell dos Santos-Silva,
• Mariana Farias Alves-Silva,
• Alianda Maira Cornélio,
• Matheus de Freitas Fernandes-Pedrosa and
• Arnóbio Antônio da Silva-Júnior

Beilstein J. Nanotechnol. 2025, 16, 1633–1643, doi:10.3762/bjnano.16.115

• hydroxide. Thus, all data demonstrate a good performance of the nanoprecipitation method to generate small-sized protein-loaded polymeric nanoparticles which can be used as a novel immunoadjuvant. Experimental Material Poly(D,L-lactic acid) (D,L-PLA) 50:50 (inherent viscosity 0.63 dL·g−1 at 30 °C) was

• material was approved by the Brazilian Access Authorization and Dispatch Component of Genetic Patrimony (CGen) (Process 010844/2013-9, 25 October 2013). The venom was weighed and dissolved with PBS at 1 mg/mL, aliquoted, and stored at −20 °C until used. Preparation of cationic PLA nanoparticles for Tityus

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• for MP monitoring. Despite high laboratory scale efficiencies, there are several challenges such as material scalability, environmental safety, regulatory frameworks, and real water applicability. This study proposes future directions for sustainable nanotechnology deployment, including green

• associated modules. The efficiency of a membrane system is primarily governed by the material used in its construction. Enhancing membranes with functional nanomaterials provides a promising path to boost permeability, reduce fouling, and increase both mechanical and thermal durability, while also enabling

• innovative solutions in MPs remediation. You et al. [119] synthesized a robust composite material, ZIF-8@Aerogel, by growing Zn-based MOF ZIF-8 directly onto wood-derived aerogel fibres. This composite demonstrated effective MP removal in both freshwater and seawater simulations. Specifically, it achieved a

Bioinspired polypropylene-based functionally graded materials and metamaterials modeling the mistletoe–host interface

• Lina M. Rojas González,
• Naeim Ghavidelnia,
• Christoph Eberl and
• Max D. Mylo

Beilstein J. Nanotechnol. 2025, 16, 1592–1606, doi:10.3762/bjnano.16.113

• gradient that bridges the mechanical differences between the adjacent tissues. These characteristics of the mistletoe–host interface can be transferred to functionally graded polymeric materials. Using extrusion molding and hot pressing, we developed a material system that combines pure and glass-fiber

• local strain behavior and the failure point. Moreover, this phenomenon was transferred to metamaterial structures where the material gradient counteracts the geometric gradient (beam thickness). The results highlight the effective anchoring method of mistletoe through graded structuring of the interface

• with the host branch and provide a framework for creating bioinspired functionally graded material systems with programmable local strain and failure behavior. Keywords: bioinspiration; digital image correlation; fiber-reinforced polypropylene; materials interface; programmable failure; Introduction

Photocatalytic degradation of ofloxacin in water assisted by TiO₂ nanowires on carbon cloth: contributions of H₂O₂ addition and substrate absorbability

• Iram Hussain,
• Lisha Zhang,
• Zhizhen Ye and
• Jin-Ming Wu

Beilstein J. Nanotechnol. 2025, 16, 1567–1579, doi:10.3762/bjnano.16.111

• than that of 10–20 ppm adopted by most studies, highlighting the advantages of the one-dimensional TiO2 material on an adsorptive substrate as a photocatalyst. Experimental Materials and reagents Carbon cloth with a purity of 99.8% was provided by Shanghai Hesen Industry Company Limited, China

Modeling magnetic properties of cobalt nanofilms used as a component of spin hybrid superconductor–ferromagnetic structures

• Aleksey Fedotov,
• Olesya Severyukhina,
• Anastasia Salomatina and
• Anatolie Sidorenko

Beilstein J. Nanotechnol. 2025, 16, 1557–1566, doi:10.3762/bjnano.16.110

• material structure corresponded to a face-centered cubic crystal lattice (fcc). The size of the system in the first problem was small at 500 atoms (5 × 5 × 5 elementary crystal cells) and was due to the study of a similar system in [22]. The appearance of the modeled cobalt crystallite and the magnetic

• nanofilm increases, the modeled system approaches a bulk material in terms of its physical properties. That is why, from the point of view of functional characteristics, thin-film ferromagnetic nanostructures are of the greatest interest. Analysis of the graphs in Figure 5 shows that for the whole series

Transient electronics for sustainability: Emerging technologies and future directions

• Jae-Young Bae,
• Myung-Kyun Choi and
• Seung-Kyun Kang

Beilstein J. Nanotechnol. 2025, 16, 1545–1556, doi:10.3762/bjnano.16.109

• stimulators, and drug delivery vehicles, as well as environmentally benign electronics for soil or aquatic disposal. Despite their potential, key challenges remain in expanding the material set for diverse functionalities, achieving high-density integration for advanced operations, and enabling precise

• ; encapsulation; fabrication strategy; transient electronics; Introduction In recent years, a growing global concern has emerged regarding the unintended consequences of material longevity on sustainability initiatives, particularly in light of the escalating crisis of plastic waste accumulation in landfills and

• electronic devices has created fertile ground for the convergence of flexible electronics with lifetime-controllable material systems [13]. This confluence has given rise to the emerging field of transient electronics, that is, devices engineered to function over a defined time window before undergoing

Influence of laser beam profile on morphology and optical properties of silicon nanoparticles formed by laser ablation in liquid

• Natalie Tarasenka,
• Vladislav Kornev,
• Alena Nevar and
• Nikolai Tarasenko

Beilstein J. Nanotechnol. 2025, 16, 1533–1544, doi:10.3762/bjnano.16.108

• its prominent optical and electronic properties, is the most widely used semiconductor material in many fields of microelectronics, optics, photovoltaics, and molecular sensing. Nevertheless, even despite its widespread application, the interest in silicon-based structures, especially having sizes in

• laser beam energy distribution (Gauss, Bessel, or annular) for the synthesis of silicon nanomaterials of different shapes by laser ablation in a liquid. The advantages of laser beams with Bessel and annular profiles were demonstrated earlier in the fields of material processing, such as microdrilling

• -uniform energy distribution, which will affect plasma generation and confinement, the hydrodynamic trajectory of the ejected target material and pressure relaxation, as well as plasma and cavitation bubble propagation and temporal evolution. In the case of a Bessel beam, the focusing with an axicon

Dendrimer-modified carbon nanotubes for the removal and recovery of heavy metal ions from water

• Thao Quynh Ngan Tran,
• Huu Trung Nguyen,
• Subodh Kumar and
• Xuan Thang Cao

Beilstein J. Nanotechnol. 2025, 16, 1522–1532, doi:10.3762/bjnano.16.107

• Abstract Effective removal of trace heavy metal ions from aqueous bodies is a pressing problem and requires significant improvement in the area of absorbent material in terms of removal efficiency and sustainability. We propose an efficient strategy to enhance the adsorption efficiency of carbon nanotubes

• (Scheme 1). This first step is crucial to ensure a high growth rate of dendrimers in subsequent steps by the repeated reaction of MA and ethylene diamine (EDA). We have characterized the CNTs-MA material by Raman spectroscopy to find the degree of functionalization, and the results are depicted in Figure

• 0.45 µm PTFE membrane, then thoroughly washed several times with deionized water followed by ethanol to remove any unreacted MA and residual DES. The washed material was subsequently dried in an oven at 45 °C overnight. The CNTs-MA (100 mg) was dispersed in 10 mL of methanol under a nitrogen atmosphere

Nanomaterials for biomedical applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Filippo Pierini,
• Seda Kizilel and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 1499–1503, doi:10.3762/bjnano.16.105

• . Drugs or genetic material can be carried by these cylindrical nanoparticles and directed towards specific cells through external stimuli such as a magnetic field or light [12]. A new nanoscale drug delivery system has been developed by using carbon nanotubes and a carbon nanotube–graphene hybrid to more

• well-suited for orthopedic implants. Likewise, the addition of silver nanoparticles provides antibacterial properties for the material. This action is helping to prevent infection during the recovery time [28][29]. One of the major advantages of using nanomaterials in tissue engineering is that they

• material to meet specific requirements, whether to attack cancer cells, allow tissue regrowth, or eliminate bacteria from a surgical site. Since nanoparticles are extremely small, they have the potential to interact with cells and enable cellular events. Even though these technologies are intricate, their

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• foundational understanding, without investigating the extensive details that other reviews have already explored. The fundamental chemical and physical aspects of pulsed laser ablation (PLA) processes, with a focus on the evolution of material from the target to the deposited film, were explained by Ashfold et

• comprehensive understanding of the process flow, from the laser-induced ejection of material into the gas phase, through its processing and movement in the plume, to its eventual deposition onto a substrate. Figure 1 shows key developments in thin film synthesis and laser-based processing from 1909 to 2025

• [12]. The size, shape, and composition of these nanomaterials can be controlled by adjusting experimental parameters such as laser settings, liquid medium, and target material. Additionally, the preparation of doped and multicomponent semiconductor nanostructures could expand LAL’s potential in

The role of biochar in combating microplastic pollution: a bibliometric analysis in environmental contexts

• Tuan Minh Truong Dang,
• Thao Thu Thi Huynh,
• Guo-Ping Chang-Chien and
• Ha Manh Bui

Beilstein J. Nanotechnol. 2025, 16, 1401–1416, doi:10.3762/bjnano.16.102

• , and disrupt microbial diversity and nutrient cycling. Biochar, a stable and eco-friendly material, has demonstrated effectiveness in mitigating these effects by restoring soil chemistry, enhancing microbial diversity and improving crop productivity. Recent studies report that biochar increases crop

• combined with fluidized bed treatment achieved 99.2% MP removal, while granular activated carbon coupled with a fixed-column system attained 95.2% removal efficiency [15][16]. Biochar (BC) has emerged as a promising material for environmental remediation, offering benefits such as pollutant adsorption

• . This underscores the necessity of interdisciplinary research integrating material science, agriculture, and microbiology in biochar–MP–plant interactions. Three primary research trajectories emerge from the keyword analysis: Investigating how different biochar synthesis methods influence

Parylene-coated platinum nanowire electrodes for biomolecular sensing applications

• Chao Liu,
• Peker Milas,
• Michael G. Spencer and
• Birol Ozturk

Beilstein J. Nanotechnol. 2025, 16, 1392–1400, doi:10.3762/bjnano.16.101

• [22]. Due to these attributes, parylene-C, along with other variants of parylene, has been extensively utilized in the protection of electronic devices and surface modification of biomedical devices [23]. In this study, platinum was chosen as the DENA growth material due to its exceptional

Synthesis and antibacterial properties of nanosilver-modified cellulose triacetate membranes for seawater desalination

• Lei Wang,
• Shizhe Li,
• Kexin Xu,
• Wenjun Li,
• Ying Li and
• Gang Liu

Beilstein J. Nanotechnol. 2025, 16, 1380–1391, doi:10.3762/bjnano.16.100

• fibers boast exceptional hydrophilicity, facile film-forming ability, high salt retention rate, cost effectiveness, environmental friendliness, and resistance to chlorine; making it a promising material for water desalination [25][26][27]. However, CTA is susceptible to erosion and degradation by

• and Discussion Structure of membrane material To verify the target structure of the synthesized material, Fourier-transform infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy (NMR) were conducted, with the spectra depicted in Figure 1 and Figure 2, respectively. The FTIR bands

• antibacterial properties of our material, we conducted a detailed comparison with existing literature on the use of Ag to enhance the antibacterial properties of desalination membranes. This comparison encompasses the types of bacteria inhibited and the various forms in which Ag exists, including AgNPs, Ag

Automated collection and categorisation of STM images and STS spectra with and without machine learning

• Dylan Stewart Barker and
• Adam Sweetman

Beilstein J. Nanotechnol. 2025, 16, 1367–1379, doi:10.3762/bjnano.16.99

• features (e.g. molecular orbitals in the case of molecular samples) within the material. As for STM imaging, the sharpness and overall tip shape is crucial in optimising the spatial resolution of STS measurements; sharp tips result in localised tunnelling through a single position, whereas blunt or

• atomic resolution was obtained in STM feedback. SnPc was deposited onto the Au(111) surface using a custom-built evaporator, where the powdered source material is contained within a glass crucible using glass wool, around which a coil of tantalum wire is wound, providing a source of heat for the crucible

Wavelength-dependent correlation of LIPSS periodicity and laser penetration depth in stainless steel

• Nitin Chaudhary,
• Chavan Akash Naik,
• Shilpa Mangalassery,
• Jai Prakash Gautam and
• Sri Ram Gopal Naraharisetty

Beilstein J. Nanotechnol. 2025, 16, 1302–1315, doi:10.3762/bjnano.16.95

• 2000 nm, reaching a peak at approximately 13 µm, and subsequently decreases. This distinctive correlation underscores the role of plasma material reorganizational effects in LIPSS formation at higher wavelengths, presenting a new experimental observation to the existing literature. The findings enhance

• our comprehension of laser–material interactions and hold potential implications for surface engineering and material science applications. Keywords: cross section of LIPSS; high spatial frequency LIPSS (HSFL); laser-induced periodic surface structures (LIPSS); low spatial frequency LIPSS (LSFL

• modulation of the net localized energy distribution on the surface, and this field absorption is manifested as LIPSS on the surface. This process depends on several experimental factors, namely, incident wavelength, polarization, material dielectric, dielectric, fluence of the laser, pulse width, repetition

Enhancing the photoelectrochemical performance of BiOI-derived BiVO₄ films by controlled-intensity current electrodeposition

• Huu Phuc Dang,
• Khanh Quang Nguyen,
• Nguyen Thi Mai Tho and
• Tran Le

Beilstein J. Nanotechnol. 2025, 16, 1289–1301, doi:10.3762/bjnano.16.94

• limited by material challenges, including insufficient light absorption, high electron–hole recombination rates, and poor stability under operating conditions [5][6]. Among various semiconductor materials, bismuth vanadate (BiVO4) has attracted considerable interest due to its strong visible light

• produce BiVO4 thin films at high deposition rates; however, this method resulted in irregular grain structures and significant material defects, limiting the PEC performance improvements. Electrodeposition has emerged as a promising low-cost and scalable technique for BiVO4 film fabrication, offering

• synthesis parameters and PEC activity, while presenting a scalable and reproducible route for fabricating high-performance BiVO4 photoanodes. Experimental Material Bismuth nitrate pentahydrate (Bi(NO3)3·5H2O, 99.9%, Sigma-Aldrich) and vanadyl acetylacetonate (VO(acac)2, 98%, Sigma-Aldrich) were used as Bi

Acrocomia aculeata oil-loaded nanoemulsion: development, anti-inflammatory properties, and cytotoxicity evaluation

• Verónica Bautista-Robles,
• Hady Keita,
• Edgar Julián Paredes Gamero,
• Layna Tayná Brito Leite,
• Jessica de Araújo Isaías Muller,
• Mônica Cristina Toffoli Kadri,
• Ariadna Lafourcade Prada and
• Jesús Rafael Rodríguez Amado

Beilstein J. Nanotechnol. 2025, 16, 1277–1288, doi:10.3762/bjnano.16.93

• )-3,4-dihydroxyoxyoxolan-2-yl]-2-hydroxyethyl (9Z)-octadec-9-enoate; C24H44O6 HLB 4.3). Deionized water was used in the preparation of all experiments throughout the study. Plant material The fruits of Acrocomia aculeata were collected in Campo Grande, Mato Grosso do Sul, Brazil (20°50'00.1" S 54

• standard addition method and a standard reference material (Sigma, USA). The results were expressed as gallic acid equivalent. Determination of carotenoid content Carotenoid content was evaluated spectrophotometrically (Shimatsu, Japan) following the procedure described by Rodriguez-Amaya. The molar

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• ferritin. This property was exploited to design redox and pH dual-responsive ferritin nanoparticles. In drug-loaded mesoporous silica nanoparticles, ferritin was used as a gating material. It covered the pores to prevent drug release and opened only when activated by redox or pH stimuli [98]. Similarly

• vaccines and improving their immunogenicity [112]. The presence of viral nucleic acids has been a key concern in medical applications, which limits the use of viruses in living organisms. Virus-like particles are multimeric nanoparticles consisting of viral proteins but lack viral genetic material. Thus

Functional bio-packaging enhanced with nanocellulose from rice straw and cinnamon essential oil Pickering emulsion for fruit preservation

• Tuyen B. Ly,
• Duong D. T. Nguyen,
• Hieu D. Nguyen,
• Yen T. H. Nguyen,
• Bup T. A. Bui,
• Kien A. Le and
• Phung K. Le

Beilstein J. Nanotechnol. 2025, 16, 1234–1245, doi:10.3762/bjnano.16.91

• cosmetic industries. The current major gaps in research regarding these biopackaging materials are their low mechanical strength and the introduction of functional additives to enhance their range of applications. In this paper, a biopackaging material is formulated using polyvinyl alcohol with glycerol as

• a plasticizer, rice straw-derived nanocellulose as a mechanical property enhancer and cinnamon essential oil Pickering emulsion as the main functional ingredient for strawberry preservation. With the combination of nanocellulose and Pickering emulsion, this study finds that the packaging material

• radical scavenging) were observed. These bioactive properties and the inherent moisture barrier property of the packaging material are utilized for strawberry preservation with a significant preservation time of 21 days compared to control samples that start to grow a white fungus on day 11. This

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• temperature and polymer concentration [130]. Chitosan-based hydrogels have aroused a lot of interest in the health sciences field due to their biocompatibility, biodegradability, and low cytotoxicity [131]. This makes them attractive as a promising material for topical administration of biomolecules such as

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti

• Maria A. A. Bertonceli,
• Vitor D. C. Cristo,
• Ivo J. Vieira,
• Francisco J. A. Lemos,
• Arnoldo R. Façanha,
• Raimundo Braz-Filho,
• Gustavo V. T. Batista,
• Luis G. M. Basso,
• Sérgio H. Seabra,
• Thalya S. R. Nogueira,
• Felipe F. Moreira,
• Arícia L. E. M. Assis,
• Antônia E. A. Oliveira and
• Kátia V. S. Fernandes

Beilstein J. Nanotechnol. 2025, 16, 1197–1208, doi:10.3762/bjnano.16.88

• , surpassed only by cellulose. Its relevance as a biopolymer is due to its properties such as biodegradability, biocompatibility, and nontoxicity to humans, characteristics that make it widely used in various scientific and technological fields [16][17]. Therefore, we used chitosan as the coating material for

• disease vectors and the prevention of urban arboviral diseases. Materials and Methods Biological material Aedes aegypti The larvae of Ae. aegypti from the Rockefeller strain were obtained from the insectary maintained at the Biotechnology Laboratory (LBT), at the Center for Biosciences and Biotechnology

• the previously isolated and characterized rotenoids [14] were prepared using chitosan (CS Sigma-Aldrich 419419) as the coating material. For comparison purposes and identification of the best method, both common ionic gelation (CS/TPP) and controlled ionic gelation (CS/TPP–β-CD) methods were employed