Rational design of block copolymer self-assemblies in photodynamic therapy

• Maxime Demazeau,
• Laure Gibot,
• Anne-Françoise Mingotaud,
• Patricia Vicendo,
• Clément Roux and
• Barbara Lonetti

Beilstein J. Nanotechnol. 2020, 11, 180–212, doi:10.3762/bjnano.11.15

• )degradation or dissociation), the affinity to the PS and its loading and positioning inside the vector, and the possibility to introduce stimuli-responsive groups (enabling appropriate release). Similarly, the molecular weight of the polymer will have an impact on the crystallinity, the vector morphology, its

• the production of ROS upon irradiation. Stimuli-responsive vectors This strategy has been examined a lot during the last years, in a general manner for nanomedicine but also for PDT. As already explained above, the principle is to benefit from the biological medium environment to trigger the drug

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• healthy and Neiman–Pick-diseased patients. The results showed significant differences in the lysosomal population in cells between the diseased and the healthy state. The group of Andersen reported a DNA nanobox with controllable lid, and its dynamic nature potentially facilitated the stimuli-responsive

Fully amino acid-based hydrogel as potential scaffold for cell culturing and drug delivery

• Dávid Juriga,
• Evelin Sipos,
• Orsolya Hegedűs,
• Gábor Varga,
• Miklós Zrínyi,
• Krisztina S. Nagy and
• Angéla Jedlovszky-Hajdú

Beilstein J. Nanotechnol. 2019, 10, 2579–2593, doi:10.3762/bjnano.10.249

• the changing environmental conditions. Therefore, hydrogels can be used as drug delivery systems [4], implants [5][6], coatings [7][8] or scaffolds for tissue engineering [2][3][9][10]. Besides these stimuli-responsive properties, the chemical and physical structure, the mechanical properties [10] as

Features and advantages of flexible silicon nanowires for SERS applications

• Hrvoje Gebavi,
• Vlatko Gašparić,
• Dubravko Risović,
• Nikola Baran,
• Paweł Henryk Albrycht and
• Mile Ivanda

Beilstein J. Nanotechnol. 2019, 10, 725–734, doi:10.3762/bjnano.10.72

• economical for synthesis, but suffer from the lack of reproducibility due to unpredictable aggregation. Thus, researchers have implemented various ways to control the aggregation, such as bifunctional linker molecules, stimuli-responsive polymers, short single-stranded DNA chains or aptamers. Optimized solid

Targeting strategies for improving the efficacy of nanomedicine in oncology

• Gonzalo Villaverde and
• Alejandro Baeza

Beilstein J. Nanotechnol. 2019, 10, 168–181, doi:10.3762/bjnano.10.16

• scenario. Hierarchical targeting systems incorporate stimuli-responsive strategies in such a way that the targeting groups are hidden during the circulation of the carrier through the body and, therefore, the tissular accumulation occurs mainly through the EPR effect. Once the carrier reaches the tumoral

• through the incorporation of stimuli-responsive mechanisms that regulate the drug release from the nanocarrier. The incorporation of targeting moieties on the carrier surface produces a significative increase in the particle accumulation inside tumoral cells, which could improve the efficacy of the

Enhanced antineoplastic/therapeutic efficacy using 5-fluorouracil-loaded calcium phosphate nanoparticles

• Shanid Mohiyuddin,
• Saba Naqvi and
• Gopinath Packirisamy

Beilstein J. Nanotechnol. 2018, 9, 2499–2515, doi:10.3762/bjnano.9.233

• bioavailability, increased chemical stability, stimuli-responsive behaviour, pH-dependent properties, surface engineering characteristics, low or no antigenicity [16] and aqueous solubility of calcium phosphate nanoparticles greatly enhances the therapeutic efficacy. The exploitation of calcium phosphate

Closed polymer containers based on phenylboronic esters of resorcinarenes

• Tatiana Yu. Sergeeva,
• Rezeda K. Mukhitova,
• Irek R. Nizameev,
• Marsil K. Kadirov,
• Polina D. Klypina,
• Albina Y. Ziganshina and
• Alexander I. Konovalov

Beilstein J. Nanotechnol. 2018, 9, 1594–1601, doi:10.3762/bjnano.9.151

• sensing of carbohydrates and glycoproteins [5][6][7][8][9][10][11], in separation techniques [12] and in labeling and manipulation of proteins [13][14][15]. In recent years, boronic acid derivatives were applied in the construction of functional materials, i.e., stimuli-responsive devices and carriers for

• , which leads to the reconfiguration of the systems [28][29][30][31]. The synthesis of such systems is a multi-stage process that requires high amounts of reagents and time, which inhibits significantly a practical application. We propose a simple and easy method for the synthesis of stimuli-responsive

• constructed and then their tails connected by stimuli-responsive linkers to form a closed polymeric structure. The external stimulus acts on the linker, changing the structure and functionality of the system. This approach is quite simple and opens great opportunities. Employing resorcinarenes with different

High-stress study of bioinspired multifunctional PEDOT:PSS/nanoclay nanocomposites using AFM, SEM and numerical simulation

• Alfredo J. Diaz,
• Hanaul Noh,
• Tobias Meier and
• Santiago D. Solares

Beilstein J. Nanotechnol. 2017, 8, 2069–2082, doi:10.3762/bjnano.8.207

• also results in a fire-retardant material [16][17]. In recent years the focus has also shifted towards extending the functionality of nanocomposites to the design of stimuli-responsive systems [18]. In nanoclay-based systems, external stimuli reshape the organic phase conformation, and as a result, a

Non-covalent and reversible functionalization of carbon nanotubes

• Antonello Di Crescenzo,
• Valeria Ettorre and
• Antonella Fontana

Beilstein J. Nanotechnol. 2014, 5, 1675–1690, doi:10.3762/bjnano.5.178

• possibility to obtain stimuli-responsive precipitation or dispersion of CNTs. Keywords: carbon nanotubes; non-covalent functionalization; π-stacking; reversible dispersion/precipitation; Introduction Carbon nanotubes (CNTs) are hollow cylindrical tubes with nanometer scale diameters and lengths up to a few

Approaches to nanostructure control and functionalizations of polymer@silica hybrid nanograss generated by biomimetic silica mineralization on a self-assembled polyamine layer

• Jian-Jun Yuan and
• Ren-Hua Jin

Beilstein J. Nanotechnol. 2011, 2, 760–773, doi:10.3762/bjnano.2.84

• novel external stimuli-responsive smart surface [47], with the superhydrophobic surface being switched into a superhydrophilic state by means of UV irradiation. Experimental Materials LPEI with an average polymerization degree of around 505 was synthesized by the hydrolysis of the corresponding

Self-organizing bioinspired oligothiophene–oligopeptide hybrids

• Alexey K. Shaytan,
• Eva-Kathrin Schillinger,
• Elena Mena-Osteritz,
• Sylvia Schmid,
• Pavel G. Khalatur,
• Peter Bäuerle and
• Alexei R. Khokhlov

Beilstein J. Nanotechnol. 2011, 2, 525–544, doi:10.3762/bjnano.2.57

• self-assembly and stimuli-responsive properties, provided by the peptide moieties combined with the semiconducting properties of the thiophene blocks, can result in novel opportunities for the design of advanced smart materials. These bio-inspired molecular hybrids are experimentally shown to form

• of particular interest. The conjugation of oligothiophenes and amyloidogenic peptides may result in new compounds that supplement the potentially semiconducting, optical, and electroluminescent properties of oligo- and polythiophenes with the self-assembling, specific binding, and stimuli responsive