Dispersion of single-wall carbon nanotubes with supramolecular Congo red – properties of the complexes and mechanism of the interaction

• Anna Jagusiak,
• Barbara Piekarska,
• Tomasz Pańczyk,
• Małgorzata Jemioła-Rzemińska,
• Elżbieta Bielańska,
• Barbara Stopa,
• Grzegorz Zemanek,
• Janina Rybarska,
• Irena Roterman and
• Leszek Konieczny

Beilstein J. Nanotechnol. 2017, 8, 636–648, doi:10.3762/bjnano.8.68

• . Nanotubes covered with CR constitute the high capacity system that provides the possibility of binding and targeted delivery of different drugs, which can intercalate into the supramolecular, ribbon-like CR structure. The study revealed the presence of strong interactions between CR and the surface of SWNTs

Straightforward and robust synthesis of monodisperse surface-functionalized gold nanoclusters

• Silvia Varela-Aramburu,
• Richard Wirth,
• Chian-Hui Lai,
• Guillermo Orts-Gil and
• Peter H. Seeberger

Beilstein J. Nanotechnol. 2016, 7, 1278–1283, doi:10.3762/bjnano.7.118

• carbohydrates [13], proteins [14], antibodies [15] and DNA [16] are commonly used as multivalent materials for biological studies. Gold nanoparticles have been used in vivo as radiotracers [15][17], for targeted delivery [18] and, when functionalized with carboxylic acids, inhibit β-amyloid fibril growth

Nanoinformatics for environmental health and biomedicine

• Rong Liu and
• Yoram Cohen

Beilstein J. Nanotechnol. 2015, 6, 2449–2451, doi:10.3762/bjnano.6.253

• production. For example, nano-scaled systems have been designed and utilized for safe and effective targeted delivery of therapeutic agents, demonstrating the rapid advancements of nanotechnology in medical-treatment and diagnosis. At the same time, there is also mounting concern regarding the potential

Effects of surface functionalization on the adsorption of human serum albumin onto nanoparticles – a fluorescence correlation spectroscopy study

• Pauline Maffre,
• Stefan Brandholt,
• Karin Nienhaus,
• Li Shang,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2014, 5, 2036–2047, doi:10.3762/bjnano.5.212

• the bare NP surface [2][18][19][20]. To control the biological effects of NPs (e.g., to accomplish targeted delivery to specific cells or tissues or to inhibit cellular uptake), it is extremely important to understand how the properties of the NP surface can control the structure and dynamics of the

Protein-coated pH-responsive gold nanoparticles: Microwave-assisted synthesis and surface charge-dependent anticancer activity

• Dickson Joseph,
• Nisha Tyagi,
• Christian Geckeler and
• Kurt E.Geckeler

Beilstein J. Nanotechnol. 2014, 5, 1452–1462, doi:10.3762/bjnano.5.158

• delivery is a major concern, because their unspecificity hampers the growth of normal tissues and cells. The advent of nanotechnology offers a wide range of tools for the diagnosis and the treatment of this deadly disease, with new imaging techniques and the targeted delivery of therapeutic agents offering

PEGylated versus non-PEGylated magnetic nanoparticles as camptothecin delivery system

• Paula M. Castillo,
• Mario de la Mata,
• Maria F. Casula,
• José A. Sánchez-Alcázar and
• Ana P. Zaderenko

Beilstein J. Nanotechnol. 2014, 5, 1312–1319, doi:10.3762/bjnano.5.144

• different in vivo behaviour of PEGylated and non-PEGylated USM nanoparticles cannot be ruled out, as longer circulation times are expected for the PEGylated ones. Additionally, we envisage that the developed USM-PEG may form targeted-delivery systems by exploiting the free amine groups on their surface for

Nanodiamond-DGEA peptide conjugates for enhanced delivery of doxorubicin to prostate cancer

• Amanee D Salaam,
• Patrick Hwang,
• Roberus McIntosh,
• Hadiyah N Green,
• Ho-Wook Jun and
• Derrick Dean

Beilstein J. Nanotechnol. 2014, 5, 937–945, doi:10.3762/bjnano.5.107

• efficacy of cancer treatments as stand-alone therapies and in combination with standard chemotherapeutic treatment regimens. The current standard of care for metastatic cancer, doxorubicin (DOX), is presented with challenges, namely toxicity due to a lack of specificity and targeted delivery. Nano-enabled

• toxicity by incorporating mechanisms for targeted delivery of chemotherapeutics. Nanomedicine has become a viable solution for the specificity and toxicity problems with current chemotherapy treatment regimens [6][7][8][9]. Nanoparticles have facilitated tumor targeting and drug delivery in a variety of

Optimizing the synthesis of CdS/ZnS core/shell semiconductor nanocrystals for bioimaging applications

• Li-wei Liu,
• Si-yi Hu,
• Ying Pan,
• Jia-qi Zhang,
• Yue-shu Feng and
• Xi-he Zhang

Beilstein J. Nanotechnol. 2014, 5, 919–926, doi:10.3762/bjnano.5.105

• for in vitro and in vivo studies. In addition, from our study of cell viability, the prepared ternary nanocrystals were shown to have a low cytotoxicity. Given their biocompatibility and the high efficiency in relation to targeted delivery, these nanoparticles have great potential to serve as a new

In vitro toxicity and bioimaging studies of gold nanorods formulations coated with biofunctional thiol-PEG molecules and Pluronic block copolymers

• Tianxun Gong,
• Douglas Goh,
• Malini Olivo and
• Ken-Tye Yong

Beilstein J. Nanotechnol. 2014, 5, 546–553, doi:10.3762/bjnano.5.64

• the targeted delivery into biological cells. AuNRs with larger aspect ratios and smaller effective radii are excellent photo-absorbing nanoparticles, while those with a larger effective radius have a higher scattering contrast signal [2]. These remarkable absorption and scattering capabilities make

• or antigens to be linked to their surface for targeted delivery and imaging [16][17]. More importantly, one is not able to use CTAB-coated AuNRs as a carrier for drug delivery of water insoluble anti-cancer agents (e.g., doxorubicin, paclitaxel) to the cancerous area since their surface is

• gold nanoparticles formulation will be affected and this may impact their applications in sensing, imaging and targeted delivery. Thus, it is essential for the nanoparticle community to understand the effects of functionalizing PEG-SH or PEO–PPO–PEO molecules on the AuNRs surface and their

Magnetic-Fe/Fe₃O₄-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages

• Hongwang Wang,
• Tej B. Shrestha,
• Matthew T. Basel,
• Raj K. Dani,
• Gwi-Moon Seo,
• Sivasai Balivada,
• Marla M. Pyle,
• Heidy Prock,
• Olga B. Koper,
• Prem S. Thapa,
• David Moore,
• Ping Li,
• Viktor Chikan,
• Deryl L. Troyer and
• Stefan H. Bossmann

Beilstein J. Nanotechnol. 2012, 3, 444–455, doi:10.3762/bjnano.3.51

• State University, Anatomy & Physiology, Coles 228, Manhattan, KS 66506 Battelle Memorial Institute, 505 King Ave., Columbus, OH 43201 University of Kansas, KU Microscopy & Analytical Imaging Laboratory, 1043 Haworth, Lawrence, KS 66045 10.3762/bjnano.3.51 Abstract The targeted delivery of therapeutics

• to the surface of the MNPs via a carboxylesterase cleavable linker. This nanoplatform demonstrated high heating ability (SAR = 522 ± 40 W/g) in an AC-magnetic field. For the purpose of targeted delivery, this nanoplatform was loaded into tumor-homing double-stable RAW264.7 cells (mouse monocyte

• ) after targeted delivery by double-stable RAW264.7 monocyte/macrophage-like cells (Mo/Ma). A carboxylesterase-cleavable irinotecan-like SN38 prodrug was synthesized and attached to Fe/Fe3O4 magnetic nanoparticles. The prodrug concentration that was chemisorbed via dopamine-anchors to the Fe3O4 outer

Characterization of protein adsorption onto FePt nanoparticles using dual-focus fluorescence correlation spectroscopy

• Pauline Maffre,
• Karin Nienhaus,
• Faheem Amin,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2011, 2, 374–383, doi:10.3762/bjnano.2.43

• issue for various fields including biotechnology (e.g., biosensors, bioanalytics) and biomedical devices (e.g., implants and catheters). To be able to control the biological effects of NPs, such as prevention of uptake or targeted delivery to specific cells or tissues, it is of utmost importance to