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Search for "aggregation" in Full Text gives 394 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.
Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection
Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38
- the NPs as well as a high aggregation state (Figure 3A). This is because of the high viscosity of the DES, which directly affected the stirring and yielded nonspherical NP shapes. The aggregated Ag NPs are supported by pure DES in which oxygen and hydrogen atoms of ᴅ-glucose, urea, and glycerol tend
Nanomedicines against Chagas disease: a critical review
Beilstein J. Nanotechnol. 2024, 15, 333–349, doi:10.3762/bjnano.15.30
- , nanomedicines are highly susceptible to aggregation, hygroscopicity, contamination, phase transition, amorphous-to-crystalline transitions, and degradation. It is critical to maintain batch-to-batch reproducibility (in terms of mean size, polydispersity, ζ-potential, and drug loading) not only during large
Exploring the relationships between physiochemical properties of nanoparticles and cell damage to combat cancer growth using simple periodic table-based descriptors
Beilstein J. Nanotechnol. 2024, 15, 297–309, doi:10.3762/bjnano.15.27
- stability based on the aggregation phenomenon. This is well observed in MeOx NPs, where an increase in the oxidation number (χox) decreases the zeta potential. In WO3 NPs, the χox value is 6 and the zeta potential value is −23 mV; for NiO NPs, the χox value is 2, and the zeta potential value is 34.4 mV. The
- hydroxyl radicals, resulting in oxidative damage to proteins. Moreover, they can bind non-specifically to amino acid residues and replace existing metal ions at active sites of enzymes, leading to abnormal protein folding. Protein aggregation diseases are a type of neurodegenerative diseases that occur
New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water
Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9
- , and optical traits. The colorimetric method typically depends on the enzymatic properties, aggregation, and dispersion of these nanomaterials, which can be influenced by the presence of aptamers, antibodies, and other agents [4]. Among the various colorimetric test techniques, the enzymatic conversion
Fluorescent bioinspired albumin/polydopamine nanoparticles and their interactions with Escherichia coli cells
Beilstein J. Nanotechnol. 2023, 14, 1208–1224, doi:10.3762/bjnano.14.100
- , the high ionic strength of 150 mM NaCl decreased long-range effect and intensity of electrostatic interactions compared to the other solvents, thus favoring other types of interactions (such as attractive van der Waals interactions) and, therefore, aggregation. Second, the increase in salt
- increased for both BSA/DA ratios of 3 and 10 after dialysis and freeze-drying (22% and 18%, respectively) (Supporting Information File 1, Figure S1e). During water evaporation, NPs may have been brought closer, leading to the formation of irreversible interactions and slight aggregation. This only slight
- simultaneous presence of a positive charge and two additional diethylamino groups in RhBITC, which are absent in FITC. These two additional chemical moieties may have induced some weak aggregation between the negatively charged RhBITC-BSA/PDA NPs, in contrast to FITC-BSA/PDA NPs. Ox-BSA/PDA NPs were produced
Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study
Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93
- mixed with 20 mL of 0.25 M Na2CO3 under constant vigorous stirring for 30 s at room temperature (RT). HSA solution (0.1%) was subsequently added to the mixture under stirring for 5 min to avoid particle aggregation. The obtained particle suspension was separated by centrifugation (6,000g for 3 min
Sulfur nanocomposites with insecticidal effect for the control of Bactericera cockerelli
Beilstein J. Nanotechnol. 2023, 14, 1106–1115, doi:10.3762/bjnano.14.91
- processes that involve classical nucleation, aggregation, and/or Ostwald ripening [38]. Figure 6 shows a STEM micrograph of the nanomicellar structure of a rosemary NCMP composed of two immiscible phases, that is, (a) the aqueous phase formed by the sulfur nanoparticles and (b) the oily phase formed by
Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one
Beilstein J. Nanotechnol. 2023, 14, 1028–1040, doi:10.3762/bjnano.14.85
- a washing solution of 0.9% NaCl containing 0.2% HSA, particles were resuspended in 0.9% NaCl, checked via light microscopy for aggregation, and stored at 4 °C. Particle characterization To ensure that the subsequent experiments would be carried out on particles that also met the quality requirements
- showed no aggregation within the particle suspension. Exclusion of confounders, indirect phagocytosis test HbMPs showed a low autofluorescence in the FITC channel in FACS analysis, which did not influence the fluorescence of DAPI in the PI channel. Whole blood (wb) generated a very low FITC signal as
Exploring internal structures and properties of terpolymer fibers via real-space characterizations
Beilstein J. Nanotechnol. 2023, 14, 1004–1017, doi:10.3762/bjnano.14.83
- single peak, but rather an aggregation of many individual peaks [3]. Ferreira et al. made similar observations from XRD and concluded that this broad peak reflected an “ordered but not crystalline” fiber structure [6]. In addition, analytical modeling of XRD spectra suggested that the three principal
Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays
Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82
- the aggregation pattern of nanomaterials, and extrinsic factors, including surrounding medium, medium viscosity, and concentration of the nanomaterial. Most often, nanomaterials with complex three-dimensional structures have better optical and physicochemical properties for the use in colorimetry
Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics
Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75
- antigen binding ability. Improper antibody conjugation influences antigen binding affinity and specificity. Once injected into the body, the ACNPs face both physical and biological barriers (such as diffusion, flow and shear forces, aggregation, protein adsorption, phagocytic sequestration, and clearance
- increasing the antigen binding capacity and the conjugation efficiency [61]. These covalent conjugation methods are highly stable but associated with some drawbacks. These include aggregation and polymerization, cross-linking at multiple sites on the antibodies, the need for additional purification steps for
A wearable nanoscale heart sound sensor based on P(VDF-TrFE)/ZnO/GR and its application in cardiac disease detection
Beilstein J. Nanotechnol. 2023, 14, 819–833, doi:10.3762/bjnano.14.67
- . SEM images of a pure PVDF film in Figure 8a and Figure 8b exhibit filamentous fibers with a relatively smooth surface. In contrast, Figure 8c and Figure 8d show that the addition of ZnO to the P(VDF-TrFE) filaments leads to a rough and granular surface, caused by the aggregation of ZnO particles that
- embed onto the filament surface. By examining Figure 8e and Figure 8f, we observe that trace amounts of GR effectively inhibit the aggregation of ZnO particles, resulting in a smoother surface of P(VDF-TrFE)/ZnO/GR nanofilm filaments compared to P(VDF-TrFE)/ZnO. The average fiber diameters of P(VDF-TrFE
Silver nanoparticles loaded on lactose/alginate: in situ synthesis, catalytic degradation, and pH-dependent antibacterial activity
Beilstein J. Nanotechnol. 2023, 14, 781–792, doi:10.3762/bjnano.14.64
- , with the highest inhibition zone diameters recorded at pH 6 against S. aureus (10.8 ± 0.57 mm) and S. typhi (9.3 ± 1.34 mm). In contrast, the nanocomposite showed no inhibition in highly basic media (pH 11 and 12) because of the aggregation of nanoparticles, which hindered the leaching of silver into
- 10. The zeta potentials of the nanocomposite were −23.3, −27.5, and −13.3 mV at pH 4, 6, and 12, respectively, indicating that the stability of the nanocomposite was low in highly acidic and basic media, leading to the aggregation of nanoparticles. TEM images demonstrated significant variations in
- the morphology of the nanocomposite in different media. At pH 4, AgNPs aggregated to form larger particles compared to those formed at pH 6. In contrast, at pH 12, the nanocomposite was disrupted, leading to the aggregation of gel and a reduced interaction between AgNPs and the bacterial cell wall
Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments
Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63
- resulted in loss or overcoating of the surface citrate, and, in some cases, agglomeration [10]. Exposure to vitamin C and glutathione led to dissolution-accompanied aggregation of mesoporous silica CeO2 nanoparticles [35]. The shortening of ceria nanorods from 25 to 8 nm after 14 days at 200 °C was
- aggregation of nanoceria was also shown by Muhammad and co-workers [35]. TEM analysis TEM analysis was conducted on two samples, citric and β-hydroxybutyric acid, to compare to the DLS results. They were chosen to represent samples from groups one and four. In the presence of light, nanoceria exposed to
In situ magnesiothermic reduction synthesis of a Ge@C composite for high-performance lithium-ion batterie anodes
Beilstein J. Nanotechnol. 2023, 14, 751–761, doi:10.3762/bjnano.14.62
- performance of Ge-based anodes, a carbon matrix is the most popular choice to disperse nanoparticles, avoiding their aggregation and reducing the internal stress induced by volume variation, because of its flexible structure and high conductivity [30][31][32]. In our recent study, the combination of Ge
Control of morphology and crystallinity of CNTs in flame synthesis with one-dimensional reaction zone
Beilstein J. Nanotechnol. 2023, 14, 741–750, doi:10.3762/bjnano.14.61
- temperatures at lower and higher HAB values. The lowest HAB value shows the highest temperature reading, which linearly decreases with increasing HAB values. The temperature differences are expected to produce different particle size distributions due to aggregation of particles on the surface of the nickel
Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review
Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52
- developing luminescent sensors include their toxicity, ease of aggregation, photobleachability, and low capacity for adsorption of the target analyte. Numerous luminescent materials, including semiconductors, metal complexes, metal-based fluorescent nanoparticles, MOFs, and inorganic phosphors doped with
Molecular nanoarchitectonics: unification of nanotechnology and molecular/materials science
Beilstein J. Nanotechnol. 2023, 14, 434–453, doi:10.3762/bjnano.14.35
- expression through nanoarchitectonics. Shi and co-workers created nanoparticle surfactants at liquid–liquid interfaces by exploiting the interaction between nanoparticles and polymer ligands [101]. They showed that a size-dependent aggregation of nanoparticle surfactants can be generated at the interface
Evaluation of electrosynthesized reduced graphene oxide–Ni/Fe/Co-based (oxy)hydroxide catalysts towards the oxygen evolution reaction
Beilstein J. Nanotechnol. 2023, 14, 420–433, doi:10.3762/bjnano.14.34
- friendly nature [11]. Even though transition-metal-based catalysts still suffer from low surface areas [12], dissolution and aggregation of metallic phase and metal oxides during the active OER process occurs [13]. Hence, Ni-, Fe- and/or Co-based catalysts have been synthesized as hybrid catalysts with
Plasmonic nanotechnology for photothermal applications – an evaluation
Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33
- nanocomposites. A detailed investigation of the essential, but often ignored, concept of thermal, chemical, and aggregation stability of nanoparticles is another part of this review. The challenges that remain, as well as prospective directions and chemistries, regarding nanomaterials for PT conversion are
Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities
Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31
- medium [74]. Since NPs are exposed to various forces that affect their stability and size in such environments (containing electrolytes, proteins and lipids), they may tend to collapse and aggregate. Although no aggregation and turbidity were observed during the preparation stage with the naked eye and
- . In other words, in the presence of the medium for cell culture (i.e., DMEM without phenol red), the possible formation of larger structures through the aggregation of Ag NPs will cause a shift in the position of the SPR peak toward the longer-wavelength side of the spectrum. Therefore, to get an
- insight into the aggregation and the stability of the Ch/Q- and Ch/CA-Ag NPs in the cell culture medium, UV–vis absorption measurements were carried out (see Supporting Information File 1, Figure S2). As can be seen in Figure S2 (Supporting Information File 1), the SPR peak emerges at 428 and 440 nm for
The steep road to nonviral nanomedicines: Frequent challenges and culprits in designing nanoparticles for gene therapy
Beilstein J. Nanotechnol. 2023, 14, 351–361, doi:10.3762/bjnano.14.30
- ). Laser scanning or spinning disc confocal microscopy, typically used for qualitative determination of NP uptake, can provide valuable insights into relative distribution and aggregation of NPs, which has been widely used in the field of nonviral gene delivery (reported in 82% of the papers, Figure 1a
- ultracentrifugation provide ensemble detection of size distributions with their own issues and complexities (e.g., gradient-induced aggregation and pressure-induced particle reconfiguration) [65]. Determination of size on a per-particle basis, such as that obtained from NTA or the aforementioned cryo-TEM/solution AFM
Biocatalytic synthesis and ordered self-assembly of silica nanoparticles via a silica-binding peptide
Beilstein J. Nanotechnol. 2023, 14, 280–290, doi:10.3762/bjnano.14.25
- becomes growth by monomer addition to the surface of the particles. At 1 mM concentration, however, the SiBP alters this profile and delays the aggregation of early approx. 10 nm particles into larger particles (Figure 4b). The most likely mechanism for this is the SiBP binding on the surface of the
Recent progress in cancer cell membrane-based nanoparticles for biomedical applications
Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24
- different types of tumors through homotypic aggregation to homologous tissues [23]. The encapsulated NPs can specifically accumulate in the tumor tissue and reduce early clearance, thereby prolonging the residence time of the drugs they carry and reducing their systemic side effects [24]. Furthermore
- fast growth and easy metastasis [28]. After circulating tumor cells are released from the primary tumor site into the bloodstream, they participate in the main metastasis process and tend to form multicellular homoaggregates at major attachment sites [29][30]. The homotypic aggregation of cancer cells
- mediates solid tumorigenesis and metastatic behavior [31]. The mechanism of homotypic aggregation is the result of multifactorial action and is closely related to tumor-specific antigens (e.g., Thomsen–Friedenreich antigen [29], carcinoembryonic antigen [32], and glycoprotein 100 [33]) and other adhesion
Cyclodextrins as eminent constituents in nanoarchitectonics for drug delivery systems
Beilstein J. Nanotechnol. 2023, 14, 218–232, doi:10.3762/bjnano.14.21
- them, a linear polymer was constructed through consecutive inclusion of adamantane in β-CyD units. Upon further addition of poly(ethylene glycol) bearing adamantane at the terminus nanoparticles were formed (Figure 7B). In these nanoparticles, aggregation of porphyrins is suppressed because of steric
- encapsulating (a part of) the photosensitizer in the cavities, its self-aggregation was suppressed to accomplish a high quantum yield of 1O2 production. The aggregation of porphyrin was photocontrolled by using complex formation of β-CyD with photoresponsive azobenzene [78]. By delivering nitrogen oxide (NO
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