Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

• Filip Gorachinov,
• Fatima Mraiche,
• Diala Alhaj Moustafa,
• Ola Hishari,
• Yomna Ismail,
• Jensa Joseph,
• Maja Simonoska Crcarevska,
• Marija Glavas Dodov,
• Nikola Geskovski and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

• subcellular targeting, were synthesized by click coupling reactions or arranged by self-assembly and co-assembly of block copolymers. These carriers may challenge different barriers after bioresponsive cleavage of the above functionalities. One recently published example involves a micellar structure composed

Solvent-induced assembly of mono- and divalent silica nanoparticles

• Bin Liu,
• Etienne Duguet and
• Serge Ravaine

Beilstein J. Nanotechnol. 2023, 14, 52–60, doi:10.3762/bjnano.14.6

• with two patches functionalized with metal-coordination-based recognition units [20], and by co-assembly of block copolymer micelles and hard nanoparticles [21]. Particles with two patches located at opposite poles have been assembled into a Kagome lattice by hydrophobic interactions [22], into chains

• %), homodimers made of two 1-PSN with a PPSR of 0.45 (≈17.5%), homodimers made of two 1-PSN with a PPSR of 0.38 (≈23%), and also heterotrimers (≈1.5%), and homotrimers (≈1.5%) (Figure 5b). Co-assembly of 2-PSN and 1-PSN acting as chain stoppers It has been previously shown that monofunctional nanoparticles can

• deposition on TEM grids. Co-assembly of one- and two-patch silica nanoparticles The incubation of the nanoparticles in a 7:3 (vol/vol) THF/salty water mixture was carried out in 15 mL tubes under rolling motion at 60 rpm and at room temperature. The composition of the mixtures is given in Table 1

Correction: Coordination-assembled myricetin nanoarchitectonics for sustainably scavenging free radicals

• Xiaoyan Ma,
• Haoning Gong,
• Kenji Ogino,
• Xuehai Yan and
• Ruirui Xing

Beilstein J. Nanotechnol. 2022, 13, 570–571, doi:10.3762/bjnano.13.48

• , Beijing, P. R. China School of Chemical Engineering, University of Chinese Academy of Sciences, Beijing, P. R. China 10.3762/bjnano.13.48 Keywords: antioxidant; co-assembly; glutathione; myricetin; nanoarchitectonics; Correction 1: In the abbreviation of the radical cation "ABTS+", the dot indicating

Coordination-assembled myricetin nanoarchitectonics for sustainably scavenging free radicals

• Xiaoyan Ma,
• Haoning Gong,
• Kenji Ogino,
• Xuehai Yan and
• Ruirui Xing

Beilstein J. Nanotechnol. 2022, 13, 284–291, doi:10.3762/bjnano.13.23

• offers a new design to harness stable, sustainable antioxidant nanoparticles with high loading capacity, high bioavailability, and good biocompatibility as antioxidants. Keywords: antioxidant; co-assembly; glutathione; myricetin; nanoarchitectonics; Introduction Oxidative stress, caused by an imbalance

• , cysteine, and glutamic acid. The cysteine residue plays a pivotal role in protecting the body from oxidation damage; however, GSH is easily metabolized by enzymes [23]. In this work, we employed a facile co-assembly strategy to design hybrid nanoparticles as antioxidants [24][25][26][27][28][29][30][31

• shows spherical MZG nanoparticles. Size and zeta potential value of the MZG nanoparticles were 44.6 ± 26.5 nm and −23.1 ± 3.4 mV, respectively, measured by dynamic light scattering (DLS) (Figure 2b) and consistent with the TEM results. Importantly, the co-assembly mechanism was further revealed through

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• acid and functional molecule self-assembly (drug, photosensitizer) (Figure 1). In this paper, the self-assembly of single amino acids is discussed first. We then discuss the co-assembly of amino acids and their derivatives with functional components including metal ions, photosensitizers (PS), and

• and pH values [49]. Rizzo et al. studied camptothecin loaded into Fmoc-F hydrogels in the presence of haloalkyl nanotubes. Importantly, this hybrid co-assembly method could not only control the release of camptothecin in the form of active lactone, but also showed significant inhibitory activity on

• interactions contribute to co-assembly. FCNPs nanoparticles and free Ce6 were injected into the caudal vein of MCF7 tumor-bearing nude mice at different times. The assembled NPs selectively accumulated in the tumor. In addition, the fluorescence remained at the tumor site for 24 h, indicating a long residence

Layered double hydroxide/sepiolite hybrid nanoarchitectures for the controlled release of herbicides

• Ediana Paula Rebitski,
• Margarita Darder and
• Pilar Aranda

Beilstein J. Nanotechnol. 2019, 10, 1679–1690, doi:10.3762/bjnano.10.163

• palygorskite has increased, yielding nanoplatforms useful in a large number of applications from catalysis, environmental remediation, energy production and storage to biomedicine [14][18]. The co-assembly of particles can be reached through several methods, from the direct assembly of the clay to diverse

• facilitate the co-assembly process, which favors the formation of more homogeneous and, in general, better organized nanoarchitectures [12]. Layered double hydroxides (LDH), often called anionic clays, are 2D solids of the general formula [M(II)1−xM(III)x(OH)2]x+(An−)x/n·mH2O (Figure 1B), consisting of

• double oxides” in the presence of diverse species, e.g., silica nanoparticles [32]. Nanoarchitectonic materials involving the growth of LDH nanoparticles in the presence of fibrous clay silicates were patented several years ago [33]. Direct co-assembly of already formed particles of each component does

pH-mediated control over the mesostructure of ordered mesoporous materials templated by polyion complex micelles

• Emilie Molina,
• Mélody Mathonnat,
• Jason Richard,
• Patrick Lacroix-Desmazes,
• Martin In,
• Philippe Dieudonné,
• Thomas Cacciaguerra,
• Corine Gérardin and
• Nathalie Marcotte

Beilstein J. Nanotechnol. 2019, 10, 144–156, doi:10.3762/bjnano.10.14

• and neutral silicic species, resulted in more disordered framework structures with worm-like mesopore channels of uniform diameter [3], designed as MSU-X. It should be mentioned that the reported synthesis protocols made use of synchronous reaction steps involving co-assembly of the template and the

Two-dimensional carbon-based nanocomposites for photocatalytic energy generation and environmental remediation applications

• Suneel Kumar,
• Ashish Kumar,
• Ashish Bahuguna,
• Vipul Sharma and
• Venkata Krishnan

Beilstein J. Nanotechnol. 2017, 8, 1571–1600, doi:10.3762/bjnano.8.159

Luminescent supramolecular hydrogels from a tripeptide and nitrogen-doped carbon nanodots

• Maria C. Cringoli,
• Slavko Kralj,
• Marina Kurbasic,
• Massimo Urban and
• Silvia Marchesan

Beilstein J. Nanotechnol. 2017, 8, 1553–1562, doi:10.3762/bjnano.8.157

• the sustained release of the poorly soluble antibiotic ciprofloxacin [26]. Fluorescent hydrogels were formed from co-assembly with a dye into nanostructures of different morphology, depending on whether the dye was added initially to the peptide in the alkaline buffer solution, or later to the second

• rationale could also be applied to NCNDs and the tripeptide DLeu-Phe-Phe, which were evaluated for co-assembly into hydrogels following a pH trigger from alkaline to neutral. Different scenarios were envisaged: the presence of the NCNDs 1) could promote peptide self-assembly by acting as a nucleation agent

• ). In this case, self-supportive hydrogels were formed regardless of the protocol used (i.e., addition of the NCNDs to either alkaline or acidic buffer), as shown in Figure 1. Both conditions were further investigated since peptide nanostructure morphology may change significantly upon co-assembly with

STM visualisation of counterions and the effect of charges on self-assembled monolayers of macrocycles

• Tibor Kudernac,
• Natalia Shabelina,
• Wael Mamdouh,
• Sigurd Höger and
• Steven De Feyter

Beilstein J. Nanotechnol. 2011, 2, 674–680, doi:10.3762/bjnano.2.72

• . Consequently, guiding rules to achieving particular self-assembled structures are lacking. Co-assembly of charged macrocycle 2 and macrocycle 1 Despite careful and repeated purification of the sample, attempts to investigate self-assembly of macrocycle 2 at TCB/HOPG interface always yielded co-assembled

• monolayers of 2 with what we believe is the uncharged analogue 1, even when analytically pure samples of 2 were used (Figure 3). Various examples of co-assembly of shape-persistent macrocycles with additional molecules have been recently reported [17][20][21][22][23][24][25][26][27]. Note that 1 serves as a

• structures. Consequently, based on the high resolution STM images (Figure 3b), we excluded the possibility that the two different contrasts that we observe arise from different orientations of the same molecule. Therefore, we conclude that the self-assembled monolayer is indeed formed by co-assembly of 1 and