Missing links in nanomaterials research impacting productivity and perceptions

• Santosh K. Tiwari and
• Nannan Wang

Beilstein J. Nanotechnol. 2025, 16, 2168–2176, doi:10.3762/bjnano.16.149

• almost every domain of science and technology [8]. Its exceptional thermo-mechanical properties are ideal for critical sectors such as aerospace, medicine, space exploration, textiles, construction, and materials capable of operating from cryogenic temperatures up to beyond 2000 °C [8][9]. Similarly

Multifrequency AFM integrating PeakForce tapping and higher eigenmodes for heterogeneous surface characterization

• Yanping Wei,
• Jiafeng Shen,
• Yirong Yao,
• Xuke Li,
• Ming Li and
• Peiling Ke

Beilstein J. Nanotechnol. 2025, 16, 2077–2085, doi:10.3762/bjnano.16.142

• environments such as liquids [18][19]. As demonstrated by force–distance curve analyses [19], PFT enables direct extraction of quantitative mechanical properties (e.g., Young’s modulus and adhesion) for material discrimination. However, this capability is constrained by the requirement for precise probe

• withdraw with the sample surface periodically, forming a force curve. The peak force, identified within this curve, is utilized as a feedback parameter. By sustaining a constant peak force between the probe and the sample, the topography of the sample can be obtained. Quantitative mechanical properties of

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• structure similar to a fiber-reinforced elastomer, with a fibrillar nature that leads to anisotropic mechanical properties [40][41][42]. Rather than explicitly resolving individual fibers and the surrounding amorphous matrix, we represented the spatula with a coarse-grained bead network whose anisotropic

• , kb is an additional force constant in the fibril direction, and θ is the angle between the bond vector and the fibril direction. We systematically tuned the parameters k and kb so that the resulting coarse-grained network reproduced the spatula’s key mechanical properties, specifically, its Young’s

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• advancements in the controlled release of diverse bioactive compounds [5][6][7][8][9][10]. Among the various nanostructured platforms explored for these purposes, nanofibers have gained attention due to their high surface area, adjustable porosity, and robust mechanical properties, which set them apart from

The cement of the tube-dwelling polychaete Sabellaria alveolata: a complex composite adhesive material

• Emilie Duthoo,
• Aurélie Lambert,
• Pierre Becker,
• Carla Pugliese,
• Jean-Marc Baele,
• Arnaud Delfairière,
• Matthew J. Harrington and
• Patrick Flammang

Beilstein J. Nanotechnol. 2025, 16, 1998–2014, doi:10.3762/bjnano.16.138

• cement spots treated with EDTA compared to untreated spots [39]. Moreover, EDTA treatment had a strong effect on the mechanical properties of the cement [39]. Proteins involved in the adhesive system In S. alveolata, the localization of the adhesive proteins Sa-1 and Sa-3 in cement cells with

Mechanical property measurements enabled by short-term Fourier-transform of atomic force microscopy thermal deflection analysis

• Thomas Mathias,
• Roland Bennewitz and
• Philip Egberts

Beilstein J. Nanotechnol. 2025, 16, 1952–1962, doi:10.3762/bjnano.16.136

• bring physical values or interpretation to the data that is collected by the AFM, allowing operators of the technique to compare their measurements across fields [6]. CR-AFM is a technique that was established in 2008, allowing for the measurement of mechanical properties (elastic modulus and

• viscoelastic modulus) of surfaces [5]. It is particularly useful for the measurement of heterogeneous surfaces, characteristic of composite and biological materials, where understanding the interplay between microstructure and mechanical properties of the constituent materials is critical for the performance

• bring physical meaning to the experimental data. Instead, in almost every example in the literature, the frequency variation is normalized to what is measured on a surface having known mechanical properties [5][9][10]. Alongside the development of CR-AFM and the analytical models used to describe the

Further insights into the thermodynamics of linear carbon chains for temperatures ranging from 13 to 300 K

• Alexandre Rocha Paschoal,
• Thiago Alves de Moura,
• Juan S. Rodríguez-Hernández,
• Carlos William de Araujo Paschoal,
• Yoong Ahm Kim,
• Morinobu Endo and
• Paulo T. Araujo

Beilstein J. Nanotechnol. 2025, 16, 1818–1825, doi:10.3762/bjnano.16.125

• materials as well as the understanding of how such phonons relate to thermal and mechanical properties of the materials become of fundamental importance [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30]. One important point to keep in mind is

• allows thermal and mechanical properties of materials to be described by semi-classical theories (such as the Debye’s theory that describes the behavior of materials with T), and their phonon frequencies might be directly connected with relevant parameters such as the Young’s modulus, the Grüneisen

Beyond the bilayer: multilayered hygroscopic actuation in pine cone scales

• Kim Ulrich,
• Max David Mylo,
• Tom Masselter,
• Fabian Scheckenbach,
• Sophia Fischerbauer,
• Martin Nopens,
• Silja Flenner,
• Imke Greving,
• Linnea Hesse and
• Thomas Speck

Beilstein J. Nanotechnol. 2025, 16, 1695–1710, doi:10.3762/bjnano.16.119

• properties and tissue arrangements for predicting pine cone scale bending in silico. By contributing to a deeper understanding of pine cone scale biomechanics, these results also support the development of bioinspired technical applications. Future studies should refine tissue mechanical properties and

• in the following. To analyze the influence of the mechanical properties, in another simulation of the bilayer, the value of the Young's modulus of the sclerenchyma fibers was adjusted to that of the brown tissue (from 500 to 50 MPa). To analyze the influence of the Young's modulus of the brown tissue

• , together with previously published bilayer models, show that the analytical analysis of such a complex drying movement is a sensitive system of selected expansion coefficients, mechanical properties, and geometric models. It should be noted that the modeling of sorption/desorption of water via thermal

Bioinspired polypropylene-based functionally graded materials and metamaterials modeling the mistletoe–host interface

• Lina M. Rojas González,
• Naeim Ghavidelnia,
• Christoph Eberl and
• Max D. Mylo

Beilstein J. Nanotechnol. 2025, 16, 1592–1606, doi:10.3762/bjnano.16.113

• failure locations can be introduced, which should have little or no effect on the overall mechanical properties in the regular product environment. A class of materials characterized by a high degree of flexibility and distribution of material properties, which enables locally adapted behavior and, thus

• , allows for thermal and mechanical stresses to be controlled locally, is known as functionally graded materials (FGMs). By means of a gradual composition and microstructure, FGMs can reduce interfacial stress, allowing for precise tailoring of mechanical properties such as stiffness, strength, and

• manufacturing processes [10][11]. Programming the mechanical properties and fracture behavior by combining FGMs and mechanical metamaterials represents an exciting frontier in materials engineering and computational design [12][13][14]. By embedding FGMs into the hierarchical architecture of mechanical

Functional bio-packaging enhanced with nanocellulose from rice straw and cinnamon essential oil Pickering emulsion for fruit preservation

• Tuyen B. Ly,
• Duong D. T. Nguyen,
• Hieu D. Nguyen,
• Yen T. H. Nguyen,
• Bup T. A. Bui,
• Kien A. Le and
• Phung K. Le

Beilstein J. Nanotechnol. 2025, 16, 1234–1245, doi:10.3762/bjnano.16.91

• alternative materials to traditional oil-based plastic packaging that help mitigate environmental and health concerns relating to food preservation. They are used particularly in the food, pharmaceutical, and cosmetic sectors thanks to their good mechanical properties, high biocompatibility, and

• degradation byproducts [8][9]. One problem is that the hydrophilic structure of PVA gives it a high water-solubility, water uptake, and worse mechanical properties [10][11]. Different filler and nanomaterials including silica [12][13][14], graphene [15][16], and metals [17][18] have been added to PVA to

• reinforcing the nanofiber structure and providing better resistance to moisture-induced degradation [22]. Studies have shown that the addition of NC can significantly enhance the mechanical properties of PVA where tensile strength has been reported to increase from around 20 MPa to well over 30 MPa [23][24

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• properties to a gel previously composed of a more rigid and brittle network, a double network gel with an IPN structure is obtained. This approach significantly contributes to improving the mechanical properties and stability of the system [43][52]. Synthetic polymers, including acrylates [53], acrylamide

Mechanical stability of individual bacterial cells under different osmotic pressure conditions: a nanoindentation study of Pseudomonas aeruginosa

• Lizeth García-Torres,
• Idania De Alba Montero,
• Eleazar Samuel Kolosovas-Machuca,
• Facundo Ruiz,
• Sumati Bhatia,
• Jose Luis Cuellar Camacho and
• Jaime Ruiz-García

Beilstein J. Nanotechnol. 2025, 16, 1171–1183, doi:10.3762/bjnano.16.86

• hypertonic conditions. Force–volume AFM demonstrated its capacity for testing the mechanical properties of multiple bacteria at once. This mechanical nanoscale mapping allowed us to successfully discriminate the minute variations in the surface topography of bacteria (h), their mechanical resistance to

Influence of ion beam current on the structural, optical, and mechanical properties of TiO₂ coatings: ion beam-assisted vs conventional electron beam evaporation

• Agata Obstarczyk and
• Urszula Wawrzaszek

Beilstein J. Nanotechnol. 2025, 16, 1097–1112, doi:10.3762/bjnano.16.81

• , adhesive, and durable TiO2 coatings with improved optical and mechanical properties, suitable for applications requiring enhanced wear resistance. Keywords: electron beam evaporation; ion beam-assisted deposition; mechanical properties; nanocrystalline anatase; optical properties; TiO2 coatings

• measurements (Figure 7) showed that the films deposited by EBE had a hardness of about 2.4 GPa. Increasing the ion gun current from 3 to 4 A caused an increase of hardness from 3.1 to 3.5 GPa. These measurements showed that the use of IBAD in the EBE process had a favorable effect on mechanical properties of

• coating was removed from the substrate (Figure 9c). The results of the mechanical properties after annealing are shown in Table 5 and Figure 10c. Based on the SEM images of the surface morphology and cross sections of the thin films, along with the mechanical results (Table 5), Thornton’s model [66][67

Piezoelectricity of hexagonal boron nitrides improves bone tissue generation as tested on osteoblasts

• Sevin Adiguzel,
• Nilay Cicek,
• Zehra Cobandede,
• Feray B. Misirlioglu,
• Hulya Yilmaz and
• Mustafa Culha

Beilstein J. Nanotechnol. 2025, 16, 1068–1081, doi:10.3762/bjnano.16.78

• process involving osteoblastic replacement and resorption by osteoclastic cells to maintain structural integrity and mechanical properties of the bone tissue as it grows. However, in cases of fracture or degeneration, the natural self-regeneration process or inherent piezoelectricity of the body may not

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

• crystals can serve as valuable design platforms for soft materials nanoarchitectonics. Polymer nanoarchitectonics Polymers exhibit a range of mechanical properties, including those that render them malleable and pliant, thus making them suitable for utilization as soft materials. Moreover, there is a

• the control of mechanical properties by polymer design has been a significant area of interest, mechanochemistry of polymers and related molecules has recently emerged as a field of growing scientific and industrial interests [270][271][272][273]. The development of mechanochromic polymers, which

Multifunctional properties of bio-poly(butylene succinate) reinforced with multiwalled carbon nanotubes

• Volodymyr Krasinskyi,
• Krzysztof Bajer,
• Ludmila Dulebova,
• Nickolas Polychronopoulos,
• Oksana Krasinska and
• Daniel Kaczor

Beilstein J. Nanotechnol. 2025, 16, 1014–1024, doi:10.3762/bjnano.16.76

• second heating (65.5% compared to 27.3% and 9%). To evaluate the potential of using PBS-based nanocomposites with CNTs, their physical, tribological, and mechanical properties were studied (Table 3 and Table 4). The addition of CNTs to PBS at a concentration of 0.5 wt % has minimal impact on the hardness

• the structure, crystallization behavior, and rheological, tribological, physical, and mechanical properties of PBS-based nanocomposites prepared via a two-step melt compounding–dilution approach using a masterbatch. While previous studies generally report trends similar to those observed here, such as

• precise positioning of the hardness tester at a right angle to the specimen surface. Mechanical properties tests under static tension were conducted using a TIRAtest 27025 testing machine (TIRA Maschinenbau GmbH, Schalkau, Germany). Maximum stress (Rm), stress at break (Rb), tensile modulus (Et), strain

Shape, membrane morphology, and morphodynamic response of metabolically active human mitochondria revealed by scanning ion conductance microscopy

• Eric Lieberwirth,
• Anja Schaeper,
• Regina Lange,
• Ingo Barke,
• Simone Baltrusch and
• Sylvia Speller

Beilstein J. Nanotechnol. 2025, 16, 951–967, doi:10.3762/bjnano.16.73

• isolated mitochondria. Remarkably, the geometric and mechanical properties of microtubules are comparable to those of the nanopipette. Microtubules are hollow structures with an opening diameter of 18 nm and a total diameter of 25–30 nm [42][43]. Their pushing force, in the range of 3–4 pN [44], is similar

Facile one-step radio frequency magnetron sputtering of Ni/NiO on stainless steel for an efficient electrode for hydrogen evolution reaction

• Ha Huu Do,
• Khac Binh Nguyen,
• Phuong N. Nguyen and
• Hoai Phuong Pham

Beilstein J. Nanotechnol. 2025, 16, 837–846, doi:10.3762/bjnano.16.63

• substrates such as nickel foam (NF), carbon cloth, and fluorine-doped tin oxide [27][28][29]. Also, SS displays high electrical conductivity, outstanding chemical stability, and good mechanical properties. Therefore, numerous researchers have used SS as a template to deposit nanomaterials using various

Supramolecular hydration structure of graphene-based hydrogels: density functional theory, green chemistry and interface application

• Hon Nhien Le,
• Duy Khanh Nguyen,
• Minh Triet Dang,
• Huyen Trinh Nguyen,
• Thi Bang Tam Dao,
• Trung Do Nguyen,
• Chi Nhan Ha Thuc and
• Van Hieu Le

Beilstein J. Nanotechnol. 2025, 16, 806–822, doi:10.3762/bjnano.16.61

• , leading to facile brush coating on plastic films of polylactide (PLA). Dehydrated GO-SG-ZH coating is adhered to the PLA substrate through interfacial interactions. Furthermore, antibacterial activities, coating stability, and mechanical properties of the nanocomposite materials were investigated and

• coating stability in environments simulating aqueous food. Mechanical properties of polylactide films with nanosilica-based and graphene-based coatings The thin coatings of SG and GO-SG-ZH considerably affected the mechanical properties of plastic films. Tensile testing results of blank PLA, SG/PLA, and

• elemental composition of the GO-SG-ZH coating on the PLA substrate. Mechanical properties of blank PLA, SG/PLA, and GO-SG-ZH/PLA thin films. Supporting Information Figure of SEM-EDS analyses of graphene-based powder and hydrogel, figures of nanocomposite hydrogel and its dispersions in water, figures and

Synthesis of a multicomponent cellulose-based adsorbent for tetracycline removal from aquaculture water

• Uyen Bao Tran,
• Ngoc Thanh Vo-Tran,
• Khai The Truong,
• Dat Anh Nguyen,
• Quang Nhat Tran,
• Huu-Quang Nguyen,
• Jaebeom Lee and
• Hai Son Truong-Lam

Beilstein J. Nanotechnol. 2025, 16, 728–739, doi:10.3762/bjnano.16.56

• monoaldehydes (e.g., formaldehyde) and other dialdehydes (C2 to C6) [37]. GA and PVA have been used as cross-linking agents in CMC-based materials to enhance selectivity, stability, and mechanical properties [38]. This method is both cost-effective and highly efficient in strengthening materials while improving

• , in a cellulose solution, Ca2+ cross-linking with Zn‒cellulose chains enhance the mechanical properties of the resulting membranes. These ions can be incorporated into the cellulose polymer matrix with an appropriate ratio, forming a controlled hydrogen bonding network that strengthens connectivity in

• interactions with functional acidic and basic groups, the cross-linking agent glutaraldehyde (GA), and an inorganic ion mixture (Ca2+ and Zn2+), which enhances the mechanical properties of the material by promoting the formation of a controlled hydrogen bonding network, thereby reinforcing the polymer matrix

Colloidal few layered graphene–tannic acid preserves the biocompatibility of periodontal ligament cells

• Teissir Ben Ammar,
• Naji Kharouf,
• Dominique Vautier,
• Housseinou Ba,
• Nivedita Sudheer,
• Philippe Lavalle and
• Vincent Ball

Beilstein J. Nanotechnol. 2025, 16, 664–677, doi:10.3762/bjnano.16.51

• significantly enhanced the flexural strength of the material, thereby improving its overall mechanical properties [6]. Additionally, another study investigated the effects of adding graphene oxide nanoplatelets (GONPs) to Portland cement. It was shown that the addition of 1 wt % GONPs improved surface

Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Muhammad Waqas,
• Ahsan Nazir and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 591–612, doi:10.3762/bjnano.16.46

• , produced by silkworms, beetles, mites, and spiders [14]. Silk is an FDA-approved biomaterial for medical applications [15]. SF has distinctive physical, chemical, and mechanical properties [16]. Its characteristics, including biocompatibility, biodegradability, elasticity, solubility in water, and ease of

• (NGF) to promote bone regeneration, vascularization, and nerve integration. The scaffolds were designed with precise porosity and geometry to promote new bone growth while mimicking the structure of natural bone. The scaffold’s mechanical properties were appropriate for bone tissue application, and the

• for tissue engineering, particularly for bone, ligaments, tendons, blood vessels, and cartilage, where mechanical properties and biological interactions are crucial. SF can be fabricated into foams, films, fibers, meshes, and hydrogels, as shown in Figure 4 [97]. Films made of fibroin and collagen

Water in nanoporous hexagonal boron nitride nanosheets: a first-principles study

• Juliana A. Gonçalves,
• Ronaldo J. C. Batista and
• Marcia C. Barbosa

Beilstein J. Nanotechnol. 2025, 16, 510–519, doi:10.3762/bjnano.16.39

• , and high mechanical strength [20][21]. Additionally, it possesses unique properties compared to graphene, such as a wide bandgap, electrical insulation, and chemical inertness. Because of its remarkable mechanical properties and resistance to oxidation during the desalination process, h-BN can be used

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• interactions. Previous studies confirmed that PEG contains hydroxyl groups (–OH) that can form hydrogen bonds with the PCL carbonyl groups (C=O). These hydrogen bonds help stabilize the nanocomposite structure and improve its mechanical properties [33]. Optimization of PEG–PCL nanoparticle concentration The