Interface conditions of roughness-induced superoleophilic and superoleophobic surfaces immersed in hexadecane and ethylene glycol

• Yifan Li,
• Yunlu Pan and
• Xuezeng Zhao

Beilstein J. Nanotechnol. 2017, 8, 2504–2514, doi:10.3762/bjnano.8.250

• liquid delivery in confined systems in biological, chemical and medical applications [1]. Interface conditions can affect fluid drag in micro/nanofluidic systems. First introduced by Navier, the slip boundary condition in hydrodynamics suggests that the velocity of fluid flow at a solid–liquid interface

Bi-layer sandwich film for antibacterial catheters

• Gerhard Franz,
• Florian Schamberger,
• Hamideh Heidari Zare,
• Sara Felicitas Bröskamp and
• Dieter Jocham

Beilstein J. Nanotechnol. 2017, 8, 1982–2001, doi:10.3762/bjnano.8.199

• homogeneous film would mean co-deposition with at least two molecules, one to build up the film and one medical drug. To act as vapor, this drug has to be evaporated. None of the commonly used organic molecules (antibiotica, heparine, gendine [16][17][18]) is sufficiently stable to withstand this process

• additional incubation, catheters were placed again in fresh artificial urine for another three weeks. The silver concentration in all three samples was measured by ICP-OES using an ICP710-ES (Varian Medical Systems, Willich, Germany), which covers a range of typically more than five orders of magnitude [40

Optical techniques for cervical neoplasia detection

• Tatiana Novikova

Beilstein J. Nanotechnol. 2017, 8, 1844–1862, doi:10.3762/bjnano.8.186

• screening and diagnostics techniques. Typically it requires up to three visits to a medical professional and several weeks in total in order to obtain the diagnosis and treatment, if necessary [23]. The implementation of new optical techniques may bring an alternative to the Pap/HPV test for screening and

Synthesis and functionalization of NaGdF₄:Yb,Er@NaGdF₄ core–shell nanoparticles for possible application as multimodal contrast agents

• Dovile Baziulyte-Paulaviciene,
• Vitalijus Karabanovas,
• Marius Stasys,
• Greta Jarockyte,
• Vilius Poderys,
• Simas Sakirzanovas and
• Ricardas Rotomskis

Beilstein J. Nanotechnol. 2017, 8, 1815–1824, doi:10.3762/bjnano.8.183

• out on a 1.5 T clinical MRI scanner (Achieva, Philips Medical Systems, Best, The Netherlands) in conjunction with a Sense Flex-M coil (Philips Medical Systems, Best, The Netherlands). Dilutions of core and core–shell UCNPs (0.125, 0.25, 0.5, 1.0 mg/mL) in deionized water were prepared for T1-weighted

A nanocomplex of C₆₀ fullerene with cisplatin: design, characterization and toxicity

• Svitlana Prylutska,
• Svitlana Politenkova,
• Kateryna Afanasieva,
• Volodymyr Korolovych,
• Kateryna Bogutska,
• Andriy Sivolob,
• Larysa Skivka,
• Maxim Evstigneev,
• Viktor Kostjukov,
• Yuriy Prylutskyy and
• Uwe Ritter

Beilstein J. Nanotechnol. 2017, 8, 1494–1501, doi:10.3762/bjnano.8.149

• collected into a heparinized medical syringe. Lymphocytes were separated by centrifugation in a density gradient (Histopaque 1077, Sigma, USA) according to instructions of the manufacturer and washed twice: control lymphocytes in 0.15 M NaCl, lymphocytes that were intended for blast transformation reaction

Calcium fluoride based multifunctional nanoparticles for multimodal imaging

• Marion Straßer,
• Joachim H. X. Schrauth,
• Sofia Dembski,
• Daniel Haddad,
• Bernd Ahrens,
• Stefan Schweizer,
• Bastian Christ,
• Alevtina Cubukova,
• Marco Metzger,
• Heike Walles,
• Peter M. Jakob and
• Gerhard Sextl

Beilstein J. Nanotechnol. 2017, 8, 1484–1493, doi:10.3762/bjnano.8.148

• different imaging techniques, such as photoluminescence (PL) microscopy and magnetic resonance imaging (MRI), open new possibilities for medical imaging, e.g., in the fields of diagnostics or tissue characterization in regenerative medicine. The focus of this study is on the synthesis and characterization

• synthesis and determine the long-term stability of the CAs. No cytotoxicity of NP concentrations between 0.5 and 1 mg·mL−1 was observed after exposure to human dermal fibroblasts over 24 h. Overall this study shows, that the CaF2:(Tb3+,Gd3+) NPs are suitable for medical imaging. Keywords: calcium fluoride

• nanoparticles; magnetic resonance imaging (MRI); multifunctional nanoparticles; multimodal imaging; photoluminescence; Introduction In recent years, medical imaging has become an important approach in the fields of diagnostics, therapy and regenerative medicine. Besides the classical technology of X-ray

Characterization of ferrite nanoparticles for preparation of biocomposites

• Urszula Klekotka,
• Magdalena Rogowska,
• Dariusz Satuła and
• Beata Kalska-Szostko

Beilstein J. Nanotechnol. 2017, 8, 1257–1265, doi:10.3762/bjnano.8.127

• ferrite nanoparticles. Detailed studies in this subject on particular systems provide conclusions and give ideas as to how to apply magnetic nanoparticles in the fields of medical, biological or environment protection. Nevertheless, precise studies on the physicochemical properties of the ferrite core is

Evaluation of quantum dot conjugated antibodies for immunofluorescent labelling of cellular targets

• Jennifer E. Francis,
• David Mason and
• Raphaël Lévy

Beilstein J. Nanotechnol. 2017, 8, 1238–1249, doi:10.3762/bjnano.8.125

• this study was funded in part and DM was fully funded by the Medical Research Council (Grant number: MR/K015931/1). All of the experiments were carried out using funding from an iCASE BBSRC studentship.

Near-field surface plasmon field enhancement induced by rippled surfaces

• Mario D’Acunto,
• Francesco Fuso,
• Ruggero Micheletto,
• Makoto Naruse,
• Francesco Tantussi and
• Maria Allegrini

Beilstein J. Nanotechnol. 2017, 8, 956–967, doi:10.3762/bjnano.8.97

• , Yokohama, Japan Harvard Medical School, 64 Sydney Street, Suite 170, Cambridge, 02139 MA, USA, Network System Research Institute, National Institute of Information and Communications Technology, 4-2-1 Nukui-kita, Koganei, Tokyo 184-8795, Japan 10.3762/bjnano.8.97 Abstract The occurrence of plasmon

Vapor deposition routes to conformal polymer thin films

• Priya Moni,
• Ahmed Al-Obeidi and
• Karen K. Gleason

Beilstein J. Nanotechnol. 2017, 8, 723–735, doi:10.3762/bjnano.8.76

• substrate. Conformality has become an increasingly important characteristic in the fabrication of optoelectronic and medical devices having high aspect ratio features, 3D geometries, and textured/nanostructured surfaces. Conformal coating methods are also desired for modifying the internal surfaces of

Silicon microgrooves for contact guidance of human aortic endothelial cells

• Sara Fernández-Castillejo,
• Pilar Formentín,
• Úrsula Catalán,
• Josep Pallarès,
• Lluís F. Marsal and
• Rosa Solà

Beilstein J. Nanotechnol. 2017, 8, 675–681, doi:10.3762/bjnano.8.72

• adhesion, morphology (alignment, circularity and filopodia presence) and proliferation. Moreover, these structures exerted no cytotoxic effect. Conclusion: The results suggest that topographical patterning influences cell response. Silicon groove substrates can be used in developing medical devices with

• microscale features to mimic the endothelium in lineal vessels. Keywords: cell morphology; contact guidance; microgrooves; silicon; human aortic endothelial cells (HAECs); Introduction Micro- and nanostructured materials for medical devices have demonstrated that surface topography as well as surface

• aforementioned decrease in cell spreading. Taking all the previously mentioned data, the present work provides evidence of the influence of the silicon surface topography on the cell behaviour. The use of such substrates may be a useful tool for the development of three-dimensional medical devices with

Carbon nanotube-wrapped Fe₂O₃ anode with improved performance for lithium-ion batteries

• Guoliang Gao,
• Yan Jin,
• Qun Zeng,
• Deyu Wang and
• Cai Shen

Beilstein J. Nanotechnol. 2017, 8, 649–656, doi:10.3762/bjnano.8.69

• %), conductive carbon black (Super P, 20 wt %) and polyvinylidene fluoride (PVDF, 10 wt %) were mixed in N-methyl-2-pyrrolidone to form a uniform slurry that was and stirred for 6 h. The slurry was spread on to the surface of a copper foil using a medical blade. The casted film was heated at 110 °C for 12 h in a

Dispersion of single-wall carbon nanotubes with supramolecular Congo red – properties of the complexes and mechanism of the interaction

• Anna Jagusiak,
• Barbara Piekarska,
• Tomasz Pańczyk,
• Małgorzata Jemioła-Rzemińska,
• Elżbieta Bielańska,
• Barbara Stopa,
• Grzegorz Zemanek,
• Janina Rybarska,
• Irena Roterman and
• Leszek Konieczny

Beilstein J. Nanotechnol. 2017, 8, 636–648, doi:10.3762/bjnano.8.68

• Anna Jagusiak Barbara Piekarska Tomasz Panczyk Malgorzata Jemiola-Rzeminska Elzbieta Bielanska Barbara Stopa Grzegorz Zemanek Janina Rybarska Irena Roterman Leszek Konieczny Chair of Medical Biochemistry, Faculty of Medicine, Jagiellonian University Medical College, Kopernika 7, Kraków 31-034

• , Jagiellonian University, Krakow, Poland Department of Bioinformatics and Telemedicine, Jagiellonian University Medical College, św. Łazarza 16, Kraków 31-034, Poland 10.3762/bjnano.8.68 Abstract A method of dispersion of single-wall carbon nanotubes (SWNTs) in aqueous media using Congo red (CR) is proposed

The longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX)

• Florent Pessina and
• Denis Spitzer

Beilstein J. Nanotechnol. 2017, 8, 452–466, doi:10.3762/bjnano.8.49

• wide range of organic compounds. In particular, cocrystals of medical materials are of interest for drug enhancement and were successfully processed through SFE at the nanoscale [118]. Inorganic nanoparticles were also produced on the nanoscale through SFE by Klaumuenzer et al. [119]. ZnO was

Uptake of the proteins HTRA1 and HTRA2 by cells mediated by calcium phosphate nanoparticles

• Olga Rotan,
• Katharina N. Severin,
• Simon Pöpsel,
• Alexander Peetsch,
• Melisa Merdanovic,
• Michael Ehrmann and
• Matthias Epple

Beilstein J. Nanotechnol. 2017, 8, 381–393, doi:10.3762/bjnano.8.40

• Olga Rotan Katharina N. Severin Simon Popsel Alexander Peetsch Melisa Merdanovic Michael Ehrmann Matthias Epple Inorganic Chemistry and Center for Nanointegration Duisburg-Essen (CeNIDE), University of Duisburg-Essen, Universitaetsstr. 5-7, D-45117 Essen, Germany, Centre for Medical Biotechnology

Comparison of four methods for the biofunctionalization of gold nanorods by the introduction of sulfhydryl groups to antibodies

• Xuefeng Wang,
• Zhong Mei,
• Yanyan Wang and
• Liang Tang

Beilstein J. Nanotechnol. 2017, 8, 372–380, doi:10.3762/bjnano.8.39

• Science Foundation of Jiangsu (BK20141295), the “333” Projects of Jiangsu Province (BRA2014172), Social Development Projects of Zhenjiang (SH2015033), Key Medical Personnel of Zhenjiang, “LiuGeYi” Projects of Jiangsu Province (LGY2016055), and the Affiliated Hospital of Jiangsu University (jdfyRC2015010

Flexible photonic crystal membranes with nanoparticle high refractive index layers

• Torben Karrock,
• Moritz Paulsen and
• Martina Gerken

Beilstein J. Nanotechnol. 2017, 8, 203–209, doi:10.3762/bjnano.8.22

• is non-toxic, biocompatible and may be used for mass production in medical applications [17][18]. The mixture is cured by an organometallic cross-linking reaction that is promoted by heat resulting in an amorphous network of polymer chains. The random PDMS coils are 0.7 nm in diameter and have a

Structural and tribometric characterization of biomimetically inspired synthetic "insect adhesives"

• Matthias W. Speidel,
• Malte Kleemeier,
• Andreas Hartwig,
• Klaus Rischka,
• Angelika Ellermann,
• Rolf Daniels and
• Oliver Betz

Beilstein J. Nanotechnol. 2017, 8, 45–63, doi:10.3762/bjnano.8.6

• adhesion and easy release (peeling off) from the substrate. Whereas such a combination is difficult to attain with conventional adhesive systems, it is essential for insects for effective locomotion. Although many constructional adhesives (e.g., casein glues, adhesive tapes, medical patches and adhesive

• bonding technological properties, especially in the range of low adhesive forces. Possible fields of application are initially non-sticky tapes whose adhesiveness can be activated by compressive stress, medical (with active pharmaceutical ingredients loadable and easily (free of pain) removable) patches

• , fluid-supplied medical patches for the treatment of burns and, with respect to their adhesiveness, controllable capillarity-based adhesion devices [62]. The adhesive strengths of our synthetic "insect emulsions" of the second generation lie well within the range of tenacities measured in intact insect

Streptavidin-coated gold nanoparticles: critical role of oligonucleotides on stability and fractal aggregation

• Roberta D'Agata,
• Pasquale Palladino and
• Giuseppe Spoto

Beilstein J. Nanotechnol. 2017, 8, 1–11, doi:10.3762/bjnano.8.1

• Andrea Doria 6, I-95125, Catania, Italy 10.3762/bjnano.8.1 Abstract Gold nanoparticles (AuNPs) exhibit unique properties that can be modulated through a tailored surface functionalization, enabling their targeted use in biochemical sensing and medical diagnostics. In particular, streptavidin-modified

When the going gets rough – studying the effect of surface roughness on the adhesive abilities of tree frogs

• Niall Crawford,
• Thomas Endlein,
• Jonathan T. Pham,
• Mathis Riehle and
• W. Jon P. Barnes

Beilstein J. Nanotechnol. 2016, 7, 2116–2131, doi:10.3762/bjnano.7.201

• medical field, as Chen et al. already demonstrated their potential for use as surgical graspers [54]. Experimental Experimental animals Tree frogs Litoria caerulea (n = 8), were used in these investigations. Their mass was 16.7 ± 6.5 g (mean ± standard deviation) and snout-vent length 57.6 ± 5.5 mm. The

A novel electrochemical nanobiosensor for the ultrasensitive and specific detection of femtomolar-level gastric cancer biomarker miRNA-106a

• Maryam Daneshpour,
• Kobra Omidfar and
• Hossein Ghanbarian

Beilstein J. Nanotechnol. 2016, 7, 2023–2036, doi:10.3762/bjnano.7.193

• Maryam Daneshpour Kobra Omidfar Hossein Ghanbarian Biotechnology Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran

• , Iran, Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Biotechnology, School of

• Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran 10.3762/bjnano.7.193 Abstract Gastric cancer (GC) is the second leading cause of cancer-related deaths all over the world. miR-106a is a circulatory oncogenic microRNA (miRNA), which overexpresses in various

Controlled supramolecular structure of guanosine monophosphate in the interlayer space of layered double hydroxide

• Gyeong-Hyeon Gwak,
• Istvan Kocsis,
• Yves-Marie Legrand,
• Mihail Barboiu and
• Jae-Min Oh

Beilstein J. Nanotechnol. 2016, 7, 1928–1935, doi:10.3762/bjnano.7.184

• Gyeong-Hyeon Gwak Istvan Kocsis Yves-Marie Legrand Mihail Barboiu Jae-Min Oh Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, Wonju, Gangwondo, 26493, Republic of Korea, Adaptive Supramolecular Nanosystems Group, Institut Européen des Membranes

Nano- and microstructured materials for in vitro studies of the physiology of vascular cells

• Alexandra M. Greiner,
• Adria Sales,
• Hao Chen,
• Sarah A. Biela,
• Dieter Kaufmann and
• Ralf Kemkemer

Beilstein J. Nanotechnol. 2016, 7, 1620–1641, doi:10.3762/bjnano.7.155

•  2). They are key players in cardiovascular diseases and are the cells getting in immediate contact with many cardio-vascular medical devices such as stents. The integrity of the endothelia cell layer is essential for avoiding thrombosis. The detailed understanding of the responses of ECs and SMCs to

• different physical and chemical properties of an adhesive surface may lead to a better understanding of their biology and the origin of vascular diseases and malfunctions. Additionally, such knowledge will be supportive for the adequate and successful design and development of medical implants, e.g., stents

• nanostructuring of medical implants for the in vivo control and stimulation of (vascular) cells behavior [8][9][10][12][201][202]. For example, it has been demonstrated that an efficient approach to improve the functions of a medical stent is the application of a morphological texture to the stent surface

Graphene-enhanced plasmonic nanohole arrays for environmental sensing in aqueous samples

• Christa Genslein,
• Peter Hausler,
• Eva-Maria Kirchner,
• Rudolf Bierl,
• Antje J. Baeumner and
• Thomas Hirsch

Beilstein J. Nanotechnol. 2016, 7, 1564–1573, doi:10.3762/bjnano.7.150

• detection limits in the environmental interesting concentration is important for water safety and direly needed. Surface plasmon resonance spectroscopy (SPR) is a widely-used technique for quantifying and characterizing biomolecular interactions in biosensors for medical diagnostics, food safety and

A composite structure based on reduced graphene oxide and metal oxide nanomaterials for chemical sensors

• Vardan Galstyan,
• Elisabetta Comini,
• Iskandar Kholmanov,
• Andrea Ponzoni,
• Veronica Sberveglieri,
• Nicola Poli,
• Guido Faglia and
• Giorgio Sberveglieri

Beilstein J. Nanotechnol. 2016, 7, 1421–1427, doi:10.3762/bjnano.7.133

• , allergies and unconsciousness [4]. Therefore, the detection of VOCs such as acetone and ethanol is essential. Nowadays, chemical and physical methods for environmental and medical diagnostics are rapidly developing. Medical monitoring technologies mainly focus on breath and blood for clinical diagnostics [5