Microplastic pollution in Himalayan lakes: assessment, risks, and sustainable remediation strategies

• Sameeksha Rawat,
• S. M. Tauseef and
• Madhuben Sharma

Beilstein J. Nanotechnol. 2025, 16, 2144–2167, doi:10.3762/bjnano.16.148

• support matrix for these composites, stabilizing the photocatalyst and enhancing its interaction with MPs [78]. Another novel strategy is the use of multifunctional nanomaterials, such as ZnO–CuO composites, which have both antibacterial and strong photocatalytic activity. These substances provide long

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• membrane applications. Thermal and crystalline analyses demonstrated improved thermal stability upon NE-βCp incorporation. Collectively, these results provide robust evidence for the feasibility of producing multifunctional nanofiber membranes that successfully integrate a polymer–lipid hybrid core

• -adherent dressings. However, for applications where cell adhesion is desired, surface modifications may be necessary. Thus, the data presented here significantly contribute to the understanding of polymer–lipid interactions in coaxial systems and pave the way for the development of multifunctional

On the road to sustainability – application of metallic nanoparticles obtained by green synthesis in dentistry: a scoping review

• Lorena Pinheiro Vasconcelos Silva,
• Joice Catiane Soares Martins,
• Israel Luís Carvalho Diniz,
• Júlio Abreu Miranda,
• Danilo Rodrigues de Souza,
• Éverton do Nascimento Alencar,
• Moan Jéfter Fernandes Costa and
• Pedro Henrique Sette-de-Souza

Beilstein J. Nanotechnol. 2025, 16, 1851–1862, doi:10.3762/bjnano.16.128

• also hold promise in regenerative dentistry. Incorporated into scaffolds, membranes, and hydrogels, they have demonstrated the ability to enhance osteogenesis and angiogenesis while simultaneously reducing microbial contamination [19]. These multifunctional biomaterials not only support bone and

Current status of using adsorbent nanomaterials for removing microplastics from water supply systems: a mini review

• Nguyen Thi Nhan and
• Tran Le Luu

Beilstein J. Nanotechnol. 2025, 16, 1837–1850, doi:10.3762/bjnano.16.127

• depends on polymer type and particle size. In contrast, nanomaterials show higher and more significant removal efficiency, in some cases exceeding 99%. Particularly, multifunctional materials (e.g., Fe3O4@PDA-lipase nanoparticles or MOFs) combine adsorption, magnetic recovery, and even catalytic

• their ability to trap MPs through adsorption or magnetic separation, materials like carbon-based nanoparticles, magnetic particles, and MOFs have demonstrated removal efficiencies exceeding 90%. Their tunable properties, reusability, and potential for multifunctional performance position them as

Electrical, photocatalytic, and sensory properties of graphene oxide and polyimide implanted with low- and medium-energy silver ions

• Josef Novák,
• Eva Štěpanovská,
• Petr Malinský,
• Vlastimil Mazánek,
• Jan Luxa,
• Ulrich Kentsch and
• Zdeněk Sofer

Beilstein J. Nanotechnol. 2025, 16, 1794–1811, doi:10.3762/bjnano.16.123

• , sensory, and photocatalytic properties of graphene oxide (GO) and polyimide (PI). Implantations were carried out with fluences ranging from 3.75 × 1012 cm−2 to 1 × 1016 cm−2. Silver ions offer excellent electrical, catalytic, and plasmonic characteristics, making them ideal for multifunctional enhancement

• multifunctional behavior of polymer systems. Keywords: ERDA; graphene oxide; ion implantation; photocatalysis; polyimide; RBS; Introduction Silver ion implantation is an effective strategy for controlling modification of the physicochemical properties of polymers and graphene-based materials. This method allows

• , and pronounced plasmonic effects in the visible spectrum [5]. These synergistic characteristics make Ag ions especially advantageous for multifunctional material modification [6]. Silver is one of the metals with the highest electrical conductivity, and its ion implantation is an effective method for

Advances of aptamers in esophageal cancer diagnosis, treatment and drug delivery

• Yang Fei,
• Hui Xu,
• Chunwei Zhang,
• Jingjing Wang and
• Yong Jin

Beilstein J. Nanotechnol. 2025, 16, 1734–1750, doi:10.3762/bjnano.16.121

• serum samples. The capture probe is an EGFR aptamer with thiol modification, and the signal probe is an anti-EGFR antibody. This multifunctional cellular probe specifically recognizes and binds to EGFR on the cell surface, inducing the formation of probe aggregates that significantly enhance resonance

• strategy for esophageal cancer and demonstrates the potential application of aptamer technology in esophageal cancer treatment. 5.2 Aptamer-functionalized drug nanocarriers A multifunctional strategy based on aptamer nanoformulation of chemotherapeutic drugs and gene therapy could protect chemotherapeutic

Multifunctional anionic nanoemulsion with linseed oil and lecithin: a preliminary approach for dry eye disease

• Niédja Fittipaldi Vasconcelos,
• Almerinda Agrelli,
• Rayane Cristine Santos da Silva,
• Carina Lucena Mendes-Marques,
• Isabel Renata de Souza Arruda,
• Priscilla Stela Santana de Oliveira,
• Mércia Liane de Oliveira and
• Giovanna Machado

Beilstein J. Nanotechnol. 2025, 16, 1711–1733, doi:10.3762/bjnano.16.120

• >75% cell viability in L929 cells and ~10% 2,2-diphenyl-1-picrylhydrazyl (DPPH) antioxidant effect. These findings support the multifunctional potential (cytocompatibility and antioxidant) of sterile OphtNE-3.66%(K1%) for the treatment of DED, emphasizing the need for in vivo studies to ensure its

• therapeutic option for this ocular condition. Artificial tear products commonly used to alleviate symptoms of DED contain various ingredients that promote osmoprotective and antioxidant effects. In this context, this study proposes the development of an ophthalmic nanoemulsion with multifunctional action

• components of tear fluid [2][89]. Based on this, an anionic profile was selected in this study to optimize retention and interaction with the ocular environment, aiming to support tear film function and alleviate dry eye symptoms through the multifunctional properties of LO. Although the physicochemical

Prospects of nanotechnology and natural products for cancer and immunotherapy

• Jan Filipe Andrade Santos,
• Marcela Bernardes Brasileiro,
• Pamela Danielle Cavalcante Barreto,
• Ligiane Aranha Rocha and
• José Adão Carvalho Nascimento Júnior

Beilstein J. Nanotechnol. 2025, 16, 1644–1667, doi:10.3762/bjnano.16.116

• , nanotechnology opens up unprecedented opportunities in cancer immunotherapy by facilitating the co-delivery of chemotherapeutic agents, immunomodulators, and gene editing tools [22]. These multifunctional platforms can modulate the tumor microenvironment, enhance antigen presentation, reverse local

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• membranes show strong promise for practical use in filtering MPs and other suspended particles from wastewater. Urso et al. [121] introduced a novel method for real-time capture and detection of NPs in a three-dimensional environment using multifunctional microrobots derived from MXene-based oxides. The

Transient electronics for sustainability: Emerging technologies and future directions

• Jae-Young Bae,
• Myung-Kyun Choi and
• Seung-Kyun Kang

Beilstein J. Nanotechnol. 2025, 16, 1545–1556, doi:10.3762/bjnano.16.109

• identifies three central areas that warrant focused development. First, the expansion of the available materials palette is essential to support diverse electronic functionalities. Second, advancements in high-density integration techniques are required to realize sophisticated, multifunctional devices

• meeting the multifunctional demands of implantable bioelectronics, which require precise control over electrical stability, mechanical flexibility, and degradation timing. A versatile material portfolio enables customized device designs tailored to operation duration, implantation site, and mechanical

• layers are also increasingly expected to provide resistance against mechanical shocks, electromagnetic shielding, and thermal dissipation. The development of new material systems capable of fulfilling these multifunctional requirements is essential for expanding the practical utility of bioresorbable

Cross-reactivities in conjugation reactions involving iron oxide nanoparticles

• Shoronia N. Cross,
• Katalin V. Korpany,
• Hanine Zakaria and
• Amy Szuchmacher Blum

Beilstein J. Nanotechnol. 2025, 16, 1504–1521, doi:10.3762/bjnano.16.106

• is also assumed that the multifunctional ligands used for the stabilization of the IONPs themselves bind with a single binding mode, which may be an incorrect assumption that can impact downstream functionalization [42]. For the purposes of multifunctional IONPs, which can possess complex, modular

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• integrating nature-inspired architectures, these smart, multifunctional biomimetic nanoparticles offer a promising path to overcome current therapeutic challenges and revolutionize precision oncology. Review 1 Types of biomimetic nanoparticles 1.1 Cell membrane-camouflaged nanoparticles Cell membranes have

• various NPs, mostly for diagnostic or multifunctional theranostic applications. 1.3.1 Albumin. Albumin is a major protein present in blood and widely studied for drug–protein interaction and nanoparticle corona formation studies. Due to its immunocompatibility, long half-life, and abundance of binding

• in which enzymes that perform sequential functions of a metabolic pathway are noncovalently associated with each other. The multifunctional enzyme complexes inspired researchers to design multienzyme complexes of their own choice. Initially, multiple enzymes were co-loaded in liposomes to perform

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• encapsulation of poorly water-soluble drugs and allowing the controlled release of the encapsulated compound [142][144]. These innovations represent a significant advance in the development of multifunctional and biocompatible nanogels, suitable for applications in oncology, gene therapy, and precision medicine

• characteristics make the system a promising multifunctional option for treating skin wounds [126]. Topical medicines are the first-choice therapy for the management of chronic autoimmune diseases, such as psoriasis and atopic dermatitis. Skin thickening, scaling, and epidermal alterations impose many obstacles

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

Multifunctional properties of bio-poly(butylene succinate) reinforced with multiwalled carbon nanotubes

• Volodymyr Krasinskyi,
• Krzysztof Bajer,
• Ludmila Dulebova,
• Nickolas Polychronopoulos,
• Oksana Krasinska and
• Daniel Kaczor

Beilstein J. Nanotechnol. 2025, 16, 1014–1024, doi:10.3762/bjnano.16.76

A calix[4]arene-based supramolecular nanoassembly targeting cancer cells and triggering the release of nitric oxide with green light

• Cristina Parisi,
• Loredana Ferreri,
• Tassia J. Martins,
• Francesca Laneri,
• Samantha Sollima,
• Antonina Azzolina,
• Antonella Cusimano,
• Nicola D’Antona,
• Grazia M. L. Consoli and
• Salvatore Sortino

Beilstein J. Nanotechnol. 2025, 16, 1003–1013, doi:10.3762/bjnano.16.75

• supported well by the reduction of the values of Φf and τ as a result of the photosensitization process competitive with the fluorescence emission. Conclusion In summary, we have designed and synthesized a multifunctional calix[4]arene, which self-assembles into nanoaggregates in water medium, which are

• alternate cycles of green light irradiation at λexc = 532 nm. [1] = 50 µM; [2] = 40 µM. T = 25 °C. Molecular structures of the multifunctional calix[4]arene 1 and the NOPD 2. (a) Chloroacetic acid, Et3N, CH2Cl2, r.t., 1 h; (b) N,N-dimethylethanolamine, THF, reflux, 24 h. (a) Butylamine, K2CO3, CH3CN, r.t

Supramolecular hydration structure of graphene-based hydrogels: density functional theory, green chemistry and interface application

• Hon Nhien Le,
• Duy Khanh Nguyen,
• Minh Triet Dang,
• Huyen Trinh Nguyen,
• Thi Bang Tam Dao,
• Trung Do Nguyen,
• Chi Nhan Ha Thuc and
• Van Hieu Le

Beilstein J. Nanotechnol. 2025, 16, 806–822, doi:10.3762/bjnano.16.61

• Education, Can Tho University, Can Tho City, 90000, Vietnam Faculty of Chemistry, University of Science, Ho Chi Minh City, 700000, Vietnam Multifunctional Materials Laboratory, University of Science, Ho Chi Minh City, 700000, Vietnam 10.3762/bjnano.16.61 Abstract Natural hydration shells are discovered to

• structures especially under external sonication and mechanical stimuli. Reversible self-assembly of graphene-based nanosheets in water is essential to many applications, such as adsorption, photocatalysis, biosensing, drug delivery, aqueous paints, and multifunctional coatings [48][49][50]. Figure 6c

• Laboratory and Multifunctional Materials Laboratory (Faculty of Materials Science and Technology, University of Science, Vietnam National University Ho Chi Minh City), Laboratory for Computational Physics (Institute for Computational Science and Artificial Intelligence, Van Lang University), and School of

Thickness dependent oxidation in CrCl₃: a scanning X-ray photoemission and Kelvin probe microscopies study

• Shafaq Kazim,
• Rahul Parmar,
• Maryam Azizinia,
• Matteo Amati,
• Muhammad Rauf,
• Andrea Di Cicco,
• Seyed Javid Rezvani,
• Dario Mastrippolito,
• Luca Ottaviano,
• Tomasz Klimczuk,
• Luca Gregoratti and
• Roberto Gunnella

Beilstein J. Nanotechnol. 2025, 16, 749–761, doi:10.3762/bjnano.16.58

• oxidation or the introduction of surface vacancies, a novel and versatile approach is unveiled for the development of low-dimensional multifunctional nanodevices. Keywords: chemical mapping; CrX3; Kelvin probe force microscopy; mechanical exfoliation; scanning photoelectron microscopy (SPEM); two

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

• Shiwani Randhawa,
• Trilok Chand Saini,
• Manik Bathla,
• Rahul Bhardwaj,
• Rubina Dhiman and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

• , these technologies also pave the way for developing therapeutic strategies aimed at inhibiting the formation of toxic AβOs. Liu et al. synthesized multifunctional superparamagnetic iron oxide nanoparticles (SPIONs) conjugated with a specific scFv antibody (W20) targeting AβOs and a class-A scavenger

• oligomerization but also in paving the way for effective therapeutic strategies against NDs. Biomimetic nanomaterials based on cell primitives for targeting AβOs The treatment of AD using conventional pharmacological agents has encountered significant challenges, prompting researchers to explore multifunctional

• -mediated mitophagy [66]. Moreover, Yuyama et al. reported that exosomes secreted by neuronal cells inhibit Aβ oligomerization by enhancing microglia-mediated Aβ clearance in vitro [86]. In a different approach, Senapati et al. developed a multifunctional liposome-based platform incorporating a novel cyclic

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

Biomimetics and bioinspired surfaces: from nature to theory and applications

• Rhainer Guillermo Ferreira,
• Thies H. Büscher,
• Manuela Rebora,
• Poramate Manoonpong,
• Zhendong Dai and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2025, 16, 418–421, doi:10.3762/bjnano.16.32

• ; microstructures; nanostructures; wettability; The surfaces of living organisms are continuously interacting with their surroundings. As a result, they encounter a variety of challenges arising from both external and internal stimuli. Consequently, these surfaces must be multifunctional and adapt to numerous

Size control of nanoparticles synthesized by pulsed laser ablation in liquids using donut-shaped beams

• Abdel Rahman Altakroury,
• Oleksandr Gatsa,
• Farbod Riahi,
• Zongwen Fu,
• Miroslava Flimelová,
• Andrei Samokhvalov,
• Stephan Barcikowski,
• Carlos Doñate-Buendía,
• Alexander V. Bulgakov and
• Bilal Gökce

Beilstein J. Nanotechnol. 2025, 16, 407–417, doi:10.3762/bjnano.16.31

• precise compositional control such as metastable binary core–shell NPs [16] and quinary Cantor high-entropy alloy NPs [17][18]. Such high-entropy nanomaterials are recently being discussed as game changers, providing disruptive design opportunities in multifunctional catalysts or magnetic materials [19

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• enhancing global visual health. Keywords: multifunctional composite; ophthalmology; photothermal nanomaterial; thermal field distribution; vapor nanobubble; Review 1 Introduction The human eye, serving as a primary organ for information acquisition, is vulnerable to various diseases over a lifetime [1

• cellular functions. Future developments may see the integration of photothermal nanomaterial therapies with viruses, receptors, antibodies, aptamers, peptides, multifunctional genes, self-assembled DNA structures, and proteins. Given the diversity and adaptability of nanomaterials, it is conceivable to

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

• modification of the synthesized MOFs and allows for the synthesis of multifunctional frameworks [32][33][34][35]. Alternatively, MOFs can undergo post-synthetic modification to achieve similar functionalization without the risk of degrading functionalized linkers during high-temperature and high-pressure MOF