Ultrasonic irradiation in the synthesis of nanohydroxyapatite: a chemically friendly technique for improving hemocompatibility and antibiofilm applications

• Juan Mendoza Turmero,
• Cristina Parra Pantoja,
• Marcos Sabino Gutiérrez,
• Milagro Fernández-Delgado,
• Claudia Alvarado-Castillo,
• Damarys Soto Gil,
• María E. Gomes Gomes,
• Yony Gutiérrez Barrios and
• Daniel Suárez Arteaga

Beilstein J. Nanotechnol. 2026, 17, 991–1015, doi:10.3762/bjnano.17.68

• and Nanotechnology, IVIC. Miranda State, Venezuela Laboratory of Hemostasis and Vascular Genetics, Center for Biophysics and Biochemistry, IVIC. Miranda State, Venezuela Nanomaterials Characterization Laboratory, Center for Materials Engineering and Nanotechnology, IVIC. Miranda State, Venezuela

• ). This apparent discrepancy, far from being contradictory, demonstrates a consistent correlation with the nature of the nanomaterials synthesized via sonochemistry. Such differences are typical for this synthesis method, where high surface roughness and internal porosity detected through gas adsorption

Materials challenges in solid-state sensors for continuous monitoring of ions in water

• Maryam Darestani-Farahani and
• Peter Kruse

Beilstein J. Nanotechnol. 2026, 17, 935–973, doi:10.3762/bjnano.17.66

• active and sensing materials for designing electrochemical and electrical devices capable of reliable, real-time ion monitoring in water. Keywords: aqueous ion sensors; biosensors; chemical sensors; nanomaterials; water quality monitoring; Introduction Access to clean water is critical for public

• to be covered in this review. This review aims to critically assess the diverse classes of nanomaterials as active layer for electrodes, FETs, and chemiresistors, and as sensing element for these solid-state electronic sensors; this is to understand how different materials influence performance

Nanocarrier strategies to overcome P-glycoprotein-mediated drug resistance in cancer therapy

• Andreina Quevedo-Enríquez,
• Katty Yi Zhang,
• Denisse Yajaira Enriquez,
• Byron Raul Inapanta,
• Roxana Noemí Peroni and
• Christian Rafael Quijia

Beilstein J. Nanotechnol. 2026, 17, 882–921, doi:10.3762/bjnano.17.64

Supramolecular one-dimensional conducting nanofibers from a C₃-symmetric tetrathiafulvalene derivative

• Yoko Tatewaki,
• Fumiya Hirose,
• Sadafumi Nishihara,
• Tomoyuki Akutagawa,
• Takayoshi Nakamura and
• Tsuyoshi Minami

Beilstein J. Nanotechnol. 2026, 17, 872–881, doi:10.3762/bjnano.17.63

• promising platforms for the development of functional nanomaterials [9][10]. In particular, when electroactive molecules are employed, one-dimensional structures formed through self-assembly are expected to be applicable as nanowire materials in molecular electronic devices. Among them, tetrathiafulvalene

• transport, and offer a useful design strategy for the development of organic conductive nanomaterials based on self-assembly. AFM images of nanorods composed of C3-symmetric MeS-TTF-Ts deposited from DMF on a mica substrate. (a) 10 μm × 10 μm; (b) 5 μm × 5 μm. AFM images of nanofibers composed of C3

Nanoparticle delivery systems for HIV pre-exposure prophylaxis (PrEP): advances and challenges

• Sonia Zahara and
• Björn M. Reinhard

Beilstein J. Nanotechnol. 2026, 17, 839–853, doi:10.3762/bjnano.17.60

• classes of nanomaterials, namely, polymeric nanoparticles, lipid-based nanoparticles, inorganic nanoparticles, and hybrid nanoparticles. Nanoparticle design considerations and targeting strategies for the individual classes are examined, and the opportunities and challenges for the different nanomaterials

• examined design criteria for four classes of nanomaterials, namely, polymeric nanoparticles, lipid-based nanoparticles, inorganic nanoparticles, and hybrid nanoparticles. Although inorganic nanoparticles can offer stability and relative ease of functionalization, they face challenges regarding

Sustainable fabrication of 2D-based devices through reuse of substrates with microfabricated electrodes

• Ying Zhang,
• Yigit Sozen,
• Esteban Zamora-Amo,
• Thomas Pucher,
• Nuria Jiménez-Arévalo,
• Zdenek Sofer,
• Yong Xie and
• Andres Castellanos-Gomez

Beilstein J. Nanotechnol. 2026, 17, 818–827, doi:10.3762/bjnano.17.58

• . Keywords: 2D device fabrication; microfabricated electrode; N-methyl-2-pyrrolidone; substrate reuse; ultrasonic cleaning; Introduction Nanoscience research often needs the fabrication of proof-of-concept devices to demonstrate applications of novel nanomaterials or to study their fundamental properties [1

• ][2][3][4]. Creating these microelectronic devices requires access to highly specialized infrastructure like cleanrooms and trained personnel [5][6][7]. Consequently, research groups focused on nanomaterials synthesis may lack the resources to integrate their novel nanomaterials into microelectronic

Tailoring Ag–Pt nanoalloys through solid-state dewetting: structural and optical insights

• Marcin Łapiński,
• Piotr Okoczuk,
• Blaž Grobiša,
• Ewa Pawlikowska,
• Amelia Rozwadowska,
• Wojciech Sadowski and
• Barbara Kościelska

Beilstein J. Nanotechnol. 2026, 17, 748–759, doi:10.3762/bjnano.17.52

• ]. The formation of nanoalloys was verified using UV–vis spectroscopy. This technique is rapid and straightforward, yet sufficiently sensitive to confirm whether alloying at the nanoscale has occurred. In nanomaterials, distinguishing between a nanoalloy and a nanocomposite is often not trivial, as the

• of conventional alloying techniques and opens new pathways for designing functional nanomaterials. Annealing the Pt on Ag bilayers (with a total thickness of 8 nm) at a temperature of 650 °C for 15 min resulted in the formation of well-defined, nearly spherical, isolated nanoislands. Chemical

Oxidative atmosphere-driven formation of single-phase spinel CuRh₂O₄ nanofibers for alkaline water oxidation

• Namhee Kim,
• Sumin Ko,
• Sohyeon Choi,
• Seoyoon Jang,
• Myung Hwa Kim and
• Dasol Jin

Beilstein J. Nanotechnol. 2026, 17, 737–743, doi:10.3762/bjnano.17.50

• spectroscopy was conducted to further examine the local bonding environments and short-range structural order of the phase-pure CuRh2O4 nanomaterials synthesized under the optimized condition (i.e., 11.1% O2). The spectrum exhibits characteristic vibrational modes at 277.6 cm−1 (F2g), 501.3 cm−1 (T2g) and

• characterization Morphology and elemental composition of the synthesized nanomaterials were examined using field-emission scanning electron microscopy (FE-SEM; JEOL JSM-6700F) and high-resolution transmission electron microscopy (HRTEM; JEOL JEM-2100F). Surface chemical states and crystallographic structures were

• as-prepared nanomaterials synthesized under different O2 concentrations. Peaks marked with • indicate the presence of secondary copper oxide phases (Cu2O). Deconvoluted AR-XPS spectra of Cu–Rh bimetallic oxides in the (a) Cu 2p and (b) Rh 3d regions. (a) Raman characterization and (b) HRTEM image of

Environmental applications of silver nanoparticles: state-of-the-art review and emerging trends

• Soni Prajapati,
• Akash Kumar and
• Ranjana Singh

Beilstein J. Nanotechnol. 2026, 17, 697–736, doi:10.3762/bjnano.17.49

• of the environment (i.e., water, air, and soil). Among the broad family of engineered nanomaterials evaluated for environmental applications, silver nanoparticles (AgNPs) have attracted exceptional attention owing to their unique combination of properties that directly address the requirements of

Protein-based custom-designed molecular nanotraps for biomedical applications

• Devid Maniglio,
• Alice Marinangeli and
• Alessandra Maria Bossi

Beilstein J. Nanotechnol. 2026, 17, 683–687, doi:10.3762/bjnano.17.47

• encoding biological functions (e.g., cell adhesion sequences such as RGD), which could lead to unintended biological interactions and off-target effects. Resulting from these considerations, the route to turn the first evidences on the potential of bioMIPs into consolidated nanomaterials for biomedical

Cellulose as a photocatalyst support material: extraction, structural features, and environmental applications

• Yee Teng Lim,
• Nur Farhana Jaafar,
• Azizul Hakim Lahuri and
• Endang Tri Wahyuni

Beilstein J. Nanotechnol. 2026, 17, 635–652, doi:10.3762/bjnano.17.44

• photoactive nanomaterials, including metal oxides and nonmetallic semiconductors, to remediate and purify water, and the use of these hybrid systems is growing steadily in water treatment applications [15]. Photocatalyst immobilization on membranes addresses key challenges by preventing photocatalyst loss

• applications [67]. At the same time, advances in synthetic methods now allow for precise control over the size, shape, and aspect ratio of metal nanomaterials, parameters that directly determine their catalytic properties. Yet, a major challenge persists because INPs are kinetically unstable and their

• with conductive polymers, depositing metallic layers on them, converting them through carbonization, and integrating them with carbon nanotubes (CNTs), each approach offering unique pathways to tailor the performance of CNCs-based conductive nanomaterials [87]. Cellulose-based nanostructured

Two-step laser synthesis of Ag@TiO₂ nanomaterials for the photocatalytic degradation of rhodamine B

• Marija Kovačević,
• Miloš Tošić,
• Rafaela Radičić,
• Vladimir Rajić,
• Nikša Krstulović,
• Miloš Momčilović and
• Sanja Živković

Beilstein J. Nanotechnol. 2026, 17, 622–634, doi:10.3762/bjnano.17.43

• pulsed laser ablation in liquids (PLAL). Initially, silver was ablated using 200 and 2000 pulses and deposited onto titanium targets via PLD. Subsequently, these modified targets were submerged in water and processed using PLAL to generate the final nanomaterials. Characterization through HRTEM, EDS, and

• provides an efficient and environmentally friendly route for the fabrication of Ag@TiO2 photocatalysts. Keywords: Ag@TiO2 nanomaterials; photocatalytic degradation; pulsed laser ablation in liquids; pulsed laser deposition; rhodamine B; Introduction Titanium dioxide has long been recognized as perhaps

• nanomaterials. These physical processes enable the direct formation of highly pure and well-dispersed nanoparticles from bulk targets without the need for chemical precursors or stabilizing agents. By fine-tuning laser parameters such as wavelength, pulse energy, and ambient conditions, researchers can tailor

Towards targeted drugs and next generation of nanomedicines

• Anna Salvati,
• Silvia Giordani and
• Wolfgang J. Parak

Beilstein J. Nanotechnol. 2026, 17, 598–601, doi:10.3762/bjnano.17.41

• target, hence improving drug efficacy while minimizing unwanted side effects. At the same time, some nanomaterials can provide new therapeutic modalities themselves and could also be used for diagnosis and imaging. Multiple drugs and therapies can be combined within the same carrier particle to

• controls available, which were decisive for the development towards clinical use. Last but not least, the field of nanosafety/nanotoxicology has set focus on the importance of counterbalancing the benefits and risks of the use of nanomaterials for potential clinical applications. Hence, while the first

• conventional drugs, one factor which is still limiting nanomedicine efficacy is their targeting capacity, especially in applications requiring extra-hepatic delivery. In fact, upon administration, most nanomaterials are sequestered by the liver, and only a small fraction of the injected nanoparticles reaches

Laser–material interactions in liquids for the synthesis of nanomaterials: current status and perspectives

• Carlos Doñate Buendia,
• Bilal Gökce and
• Leonid V. Zhigilei

Beilstein J. Nanotechnol. 2026, 17, 571–575, doi:10.3762/bjnano.17.38

• materials, including metals [2][3], oxides [4][5], semiconductors [6][7], and organics [8][9]. In addition, LSPC enables the synthesis of multicomponent nanomaterials, such as binary [10][11], ternary [12][13], and compositionally complex alloys [14][15], with a high degree of control over their composition

• development of cost-effective, high-throughput technologies. Laser processing in liquids is not merely a synthesis technique – it is an enabling platform for innovation in the development of next-generation nanomaterials, and its full potential is only beginning to be realized. Carlos Doñate Buendia, Bilal

Advances in nanotechnology applied to natural products

• Douglas Dourado,
• Fábio Rocha Formiga,
• Éverton do Nascimento Alencar and
• Franceline Reynaud

Beilstein J. Nanotechnol. 2026, 17, 555–558, doi:10.3762/bjnano.17.36

• , Brazil Laboratory of Micro and Nanostructured Systems (LASMINano), Federal University of Mato Grosso do Sul (UFMS), 79070-900, Campo Grande, MS, Brazil Université de Lorraine, CITHEFOR EA3452 - Nancy, France 10.3762/bjnano.17.36 Keywords: drug delivery; nanomaterials; nanomedicine; natural compounds

• nanomaterials, particularly metallic nanoparticles. Metallic nanoparticles, typically defined as structures with diameters between 1 and 100 nm, exhibit distinctive electrical, optical, and magnetic properties that support a broad range of applications [26]. They can be obtained via green synthesis using

Probing internal continua and atomic ultrafast charge transfer within size-controlled nanoparticles by post-collision interaction in core-hole clock spectroscopy

• Johannes Lütgert,
• Erika Giangrisostomi,
• Nomi L. A. N. Sorgenfrei and
• Alexander Föhlisch

Beilstein J. Nanotechnol. 2026, 17, 505–514, doi:10.3762/bjnano.17.33

• times are drastically reduced and converge to values below 10 as for the smallest quantum dots and to approximately 30 as for the largest quantum dots. These values are comparable to charge transfer times observed in PbS quantum dots [27] and other sulfur-containing nanomaterials [29][24]. The size

• and the absolute εr values align with theoretical predictions for nanoparticles in general and observations on ZnS nanomaterials [43][44][45]. By combining all previously discussed results in Figure 5, a comprehensive understanding of the electronic processes following resonant excitation in quantum

Upcycling agroindustrial waste into graphene oxide supports for gold nanoparticles: toward sustainable nanomaterials

• Juan Marcos Castro-Tapia,
• Selene Acosta,
• Hiram Joazet Ojeda-Galván,
• Elsie Evelyn Araujo-Palomo,
• Edgar Giovanni Villabona-Leal and
• Mildred Quintana

Beilstein J. Nanotechnol. 2026, 17, 489–504, doi:10.3762/bjnano.17.32

• of transforming agroindustrial waste into high-value graphene-based nanomaterials and highlight the potential of sustainable synthesis routes for advancing environmentally responsible carbon-based technologies. Keywords: agroindustrial waste; gold nanoparticles; graphene oxide; green synthesis

• ; hybrid nanocomposites; plasmonic nanomaterials; surface functionalization; Introduction Graphene oxide (GO), due to its unique physicochemical properties, is widely explored regarding a range of applications, including sensors, water purification, and energy storage and conversion [1][2][3][4][5]. GO is

Defects and defect-mediated engineering of two-dimensional materials: challenges and open questions

• Arkady V. Krasheninnikov,
• Matthias Batzill,
• Anouar-Akacha Delenda,
• Marija Drndić,
• Chris Ewels,
• Katharina J. Franke,
• Mahdi Ghorbani-Asl,
• Alexander Holleitner,
• Ado Jorio,
• Ute Kaiser,
• Daria Kieczka,
• Hannu-Pekka Komsa,
• Jani Kotakoski,
• Manuel Längle,
• David Lamprecht,
• Yun Liu,
• Steven G. Louie,
• Janina Maultzsch,
• Thomas Michely,
• Katherine Milton,
• Anna Niggas,
• Hanako Okuno,
• Joshua A. Robinson,
• Marika Schleberger,
• Bruno Schuler,
• Alexander Shluger,
• Kazu Suenaga,
• Kristian S. Thygesen,
• Richard A. Wilhelm,
• E. Harriet Åhlgren and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2026, 17, 454–488, doi:10.3762/bjnano.17.31

• -mediated engineering of nanomaterials for energy and quantum applications” organized by the Beilstein-Institut. Following the discussions at the symposium, here, we present the challenges and open questions in our understanding of the behavior of defective 2D materials, interaction of energetic particles

• engineering of nanomaterials for energy and quantum applications”, organized in Rüdesheim, Germany, by the Beilstein-Institut [38]. Following the symposium, in this article, we discuss the challenges and open questions, in our understanding, of the behavior of defective 2D materials, interaction of energetic

Nanoinformatics: spanning scales, systems and solutions

• Iseult Lynch,
• Diego S. T. Martinez,
• Kunal Roy and
• Georgia Melagraki

Beilstein J. Nanotechnol. 2026, 17, 423–427, doi:10.3762/bjnano.17.28

• : artificial intelligence; in silico approaches; machine learning; nanoinformatics; nanomaterials functionality; nanotoxicity; sustainability; Nanoinformatics (as an offshoot of chemoinformatics) refers to the combination of physical chemistry and materials theory with in silico approaches to address key

• questions including the prediction of (nano)materials (NM) functionality, nanomaterials fate in the environment, toxicity or therapeutic ability, and recyclability. As the properties of nanomaterials themselves span several scales, from electronic, atomistic, mesoscopic to continuum, and are highly dynamic

• emergence of artificial intelligence and machine learning approaches, both causal and generative, are opening up new opportunities for exploring the materials and chemical space to develop new as yet undiscovered nanomaterials, for optimising in parallel the functionality, safety and sustainability of

Beam shaping techniques for pulsed laser ablation in liquids: Unlocking tunable control of nanoparticle synthesis in liquids

• Sergio Molina-Prados,
• Nadezhda M. Bulgakova,
• Alexander V. Bulgakov,
• Jesus Lancis,
• Gladys Mínguez Vega and
• Carlos Doñate-Buendia

Beilstein J. Nanotechnol. 2026, 17, 309–342, doi:10.3762/bjnano.17.22

• ). Additional NPs are formed within this bubble until it collapses, releasing and ejecting the remaining NPs into the liquid [9][10][11]. Although nanomaterials can be produced by alternative physical, chemical, or biological methods [12], PLAL offers several advantages [13]. Chemical methods are effective at

• controlling NP size and shape but often require reducing agents and stabilising or capping agents to ensure colloidal stability, which may introduce impurities and raise environmental concerns. Biological routes for synthesising nanomaterials, such as those based on plant extracts, bacteria, or fungi, are

• ], core–shell structures [29][30], heterostructures [31], nanoalloys [32][33], hybrid materials [34][35], and complex multielement nanomaterials such as high-entropy alloys [36][37][38]. This method enables the synthesis of nanomaterials with exceptional purity from virtually any solid target [39

Advancing nanolithography: a comprehensive review of materials for local anodic oxidation with AFM

• Matteo Lorenzoni

Beilstein J. Nanotechnol. 2026, 17, 275–291, doi:10.3762/bjnano.17.19

• Atomic Force Microscopy: Applications in Nanomaterials, with permission from John Wiley and Sons. Copyright © 2017 Wiley-VCH GmbH. This content is not subject to CC BY 4.0. (c) AFM images of square oxide patterns fabricated by LAO on SiC before and after wet etching. (d) Height profile of the top left

Durable antimicrobial activity of fabrics functionalized with zeolite ion-exchanged nanomaterials against Staphylococcus aureus and Escherichia coli

• Perla Sánchez-López,
• Kendra Ramirez Acosta,
• Sergio Fuentes Moyado,
• Ruben Dario Cadena-Nava and
• Elena Smolentseva

Beilstein J. Nanotechnol. 2026, 17, 262–274, doi:10.3762/bjnano.17.18

• incorporation of nanomaterials onto the fabric surfaces. Antimicrobial tests reveal significant inhibition of bacterial growth, with silver-based materials demonstrating superior efficacy. Importantly, the antimicrobial effect persists after five washing cycles, demonstrating the durability of the

• nanotechnology has expanded into different areas of science, including physics, chemistry, biology, and medicine, over the past few decades [1][2]. Recently, nanoparticles (NPs), nanomaterials, and nanocomposites have been applied in various fields, including medicine and biotechnology, to reduce the recurrence

• of infections [3][4]. In this context, nanotechnology and nanomaterials offer a new alternative to combat pathogens such as viruses and bacteria. Metal NPs have intrinsic manipulatable properties that make them useful in a wide variety of research fields, including biomedicine. Different types of NPs

Multilayered hyperbolic Au/TiO₂ nanostructures for enhancing the nonlinear response around the epsilon-near-zero point

• Fernando Arturo Araiza-Sixtos,
• Mauricio Gomez-Robles,
• Rafael Salas-Montiel and
• Raúl Rangel-Rojo

Beilstein J. Nanotechnol. 2026, 17, 251–261, doi:10.3762/bjnano.17.17

• , Université de Technologie de Troyes, 10004 Troyes, France EUT+ Institute of Nanomaterials and Nanotechnologies-EUTINN, European University of Technology, European Union 10.3762/bjnano.17.17 Abstract In this work, we present the design, fabrication, and study of the optical properties of multilayered metal

Safe and sustainable by design with ML/AI: A transformative approach to advancing nanotechnology

• Georgia Melagraki

Beilstein J. Nanotechnol. 2026, 17, 176–185, doi:10.3762/bjnano.17.11

• containing them. The growing complexity of engineered nanomaterials calls for proactive strategies to mitigate potential risks while maintaining their functional benefits. The "Safe and Sustainable by Design" (SSbD) concept addresses these challenges by embedding safety measures and sustainability

• , offering unprecedented opportunities to design and develop nanomaterials with unique, tailored properties. These advances have significantly impacted diverse industrial sectors, including healthcare, energy, environmental remediation, and defence. For instance, nanoparticle-based drug delivery systems have

• , engineered nanomaterials (ENMs) have been employed for environmental applications, such as water purification and pollutant removal, addressing some of the most pressing ecological challenges [4][5]. Nanotechnology has significant applications in defence [6], particularly in the development of lightweight

From shield to spear: Charge-reversible nanocarriers in overcoming cancer therapy barriers

• Madhuri Yeduvaka,
• Pooja Mittal,
• Ameer Boyalakuntla,
• Usman Bee Shaik,
• Himanshu Sharma,
• Thakur Gurjeet Singh,
• Siva Nageswara Rao Gajula and
• Lakshmi Vineela Nalla

Beilstein J. Nanotechnol. 2026, 17, 159–175, doi:10.3762/bjnano.17.10

• , nanocarriers encompass diverse types including polymeric nanoparticles, liposomes, micelles, dendrimers, lipid-based carriers, carbon-based nanomaterials, and gold nanoparticles. They exhibit versatile structures (1–100 nm) with diverse morphologies (e.g., spherical, tubular, or conical shapes [14]). With

• and clinical evaluation processes. Ethical and environmental considerations further complicate their translation, as the degradation of by-products and long-term accumulation of synthetic nanomaterials in ecosystems necessitate thorough investigation [101]. To address these limitations, current