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Search for 青少年白发病基因IRF4_、Bcl-2 卫健委健康委 小荷医典 in Full Text gives 2582 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

New design of operational MEMS bridges for measurements of properties of FEBID-based nanostructures

  • Bartosz Pruchnik,
  • Krzysztof Kwoka,
  • Ewelina Gacka,
  • Dominik Badura,
  • Piotr Kunicki,
  • Andrzej Sierakowski,
  • Paweł Janus,
  • Tomasz Piasecki and
  • Teodor Gotszalk

Beilstein J. Nanotechnol. 2024, 15, 1273–1282, doi:10.3762/bjnano.15.103

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  • nanostructure. Keywords: FEBID; MEMS; MEMS bridge; nanowires; opMEMS; Introduction Nanoelectronics is the fastest developing branch of modern electronic technology. Reduced dimensions allow for lower power consumption of the circuit and higher operating speeds [1][2]. Even more advantages (e.g., developed
  • (Si3N4) layer was deposited via CVD. The 40 nm thick platinum paths were then patterned by lift-off photolithography. The opMEMS bridge body was defined photolithographically with a feature size of 2 µm, etched by dry oxygen plasma etching (DRIE) and then released by KOH anisotropic wet silicon etching
  • and electron columns forms a dual-beam system, which is an efficient tool for nanoprototyping [44]; hence, LiS experiments were performed using a Helios NanoLab 600i dual-beam system from FEI (Hillsboro, Oregon). SEM offers a theoretical imaging resolution better than 2 nm. Accordingly, SEM allows not
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Published 23 Oct 2024

Functional morphology of cleaning devices in the damselfly Ischnura elegans (Odonata, Coenagrionidae)

  • Silvana Piersanti,
  • Gianandrea Salerno,
  • Wencke Krings,
  • Stanislav Gorb and
  • Manuela Rebora

Beilstein J. Nanotechnol. 2024, 15, 1260–1272, doi:10.3762/bjnano.15.102

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  • , from vertebrates to arthropods, with early evolutionary origins (reviews in [1][2]). Despite the distant evolutionary relationship between vertebrates and insects, their grooming behaviors serve multiple and similar purposes, such as body cleaning and disease prevention, distribution of substances
  • Ischnura elegans males and females were collected in the field at Centro Ittiogenico del Trasimeno - Sant’Arcangelo (Perugia, Umbria region, Italy), in spring and summer 2023–2024. They were maintained for 2–3 days in a controlled climate chamber (14:10 light–dark rhythm, at a temperature of 25 ± 1 °C and
  • applied to the foretibial grooming structures. We interpreted the final images and described the material properties of the cuticle as follows: (1) Red areas are likely well-sclerotized, (2) green-to-yellow areas are less sclerotized in comparison to red ones and mechanically stable, but relatively
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Published 16 Oct 2024

The role of a tantalum interlayer in enhancing the properties of Fe3O4 thin films

  • Hai Dang Ngo,
  • Vo Doan Thanh Truong,
  • Van Qui Le,
  • Hoai Phuong Pham and
  • Thi Kim Hang Pham

Beilstein J. Nanotechnol. 2024, 15, 1253–1259, doi:10.3762/bjnano.15.101

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  • promising applications. High-quality Fe3O4 thin films are a must to achieve the goals. In this report, Fe3O4 films on different substrates (SiO2/Si(100), MgO(100), and MgO/Ta/SiO2/Si(100)) were fabricated at room temperature with radio-frequency (RF) sputtering and annealed at 450 °C for 2 h. The
  • K [1], as well as its high spin polarization with only one spin at the Fermi level, even at room temperature [2][3][4][5][6]. Fe3O4 thin films are an issue of interest and have extensive applications in Li-ion batteries, spin Seebeck devices, supercapacitors, spin Hall magnetoresistance, and the
  • substrates (referred to as samples 1, 2, and 3, recpectively). Topography images, with dimensions of 1 × 1 μm2, are shown in Figure 1. They show spherical particles with rather consistent grain sizes. In particular, samples 1 and 2 present grain size values of 7.6 ± 0.5 nm and 9.9 ± 0.6 nm, respectively
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Published 14 Oct 2024

Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids

  • Iris Renata Sousa Ribeiro,
  • Raquel Frenedoso da Silva,
  • Romênia Ramos Domingues,
  • Adriana Franco Paes Leme and
  • Mateus Borba Cardoso

Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100

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  • [1][2][3][4]. Consequently, the scientific community has focused on improving the targeting of nanoparticles (NPs) to tumor cells through surface functionalization with active groups (e.g., folate, monoclonal antibodies) [5][6][7]. However, according to the literature, only 0.7% of the injected dose
  • concentration of 10%. In this case, as the concentration of plasma in the blood is 55% [32][33], the plasma must be diluted to 5.5% to carry out the experiments. Analyses were performed in triplicate at 37 °C, with incubation times of 0, 1, 2, 3, and 24 h. The NP concentration used was 0.5 mg·mL–1. Protein
  • corona formation in cell culture medium and human plasma To verify the adsorption of proteins on the functionalized SiO2NPs, sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) experiment was performed. For this, the nanomaterials (in concentrations of 2 to 5 mg·mL–1) were incubated in
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Published 07 Oct 2024

Enhanced catalytic reduction through in situ synthesized gold nanoparticles embedded in glucosamine/alginate nanocomposites

  • Chi-Hien Dang,
  • Le-Kim-Thuy Nguyen,
  • Minh-Trong Tran,
  • Van-Dung Le,
  • Nguyen Minh Ty,
  • T. Ngoc Han Pham,
  • Hieu Vu-Quang,
  • Tran Thi Kim Chi,
  • Tran Thi Huong Giang,
  • Nguyen Thi Thanh Tu and
  • Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1227–1237, doi:10.3762/bjnano.15.99

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  • AuNPs exhibited uniform size with an average diameter of 10.0 nm. The nanocomposites facilitated the recyclable reduction of organic dyes, including 2-nitrophenol, 4-nitrophenol, and methyl orange, employing NaBH4 as the reducing agent. Kinetic studies further underscored the potential of this
  • physicochemical properties and diverse potential chemical applications [1][2][3]. The conventional synthesis of AuNPs typically involves the chemical reduction of Au3+ ions using various reducing agents and stabilizers [4][5]. However, many of these chemicals are highly reactive, posing risks to both the
  • Materials The study utilized reagents and chemicals without additional purification. Glucosamine, gold(III) chloride, calcium acetate hydrate, sodium alginate, sodium tetrahydroborate, 2-nitrophenol, 4-nitrophenol, and methyl orange were procured from Acros Scientific (Belgium). Distilled water was used
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Published 04 Oct 2024

Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles

  • André F. Lima,
  • Giselle Z. Justo and
  • Alioscka A. Sousa

Beilstein J. Nanotechnol. 2024, 15, 1208–1226, doi:10.3762/bjnano.15.98

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  • . Keywords: active targeting; cancer; nanoclusters; renal clearance; ultrasmall nanoparticles; Review 1 Introduction Nanotechnology has opened new avenues for tackling unmet challenges in medicine [1][2][3]. In the field of oncology, a notable application involves the use of engineered nanoparticles (NPs
  • modalities of actively targeted usNPs and their current applications in cancer diagnosis and treatment. 2 Inorganic ultrasmall NPs in cancer nanomedicine Important classes of inorganic usNPs under investigation for cancer nanomedicine include metallic usNPs (gold, silver), oxide and sulfide usNPs (silica
  • [78], and, potentially, modulating ultraweak nonspecific interactions with proteins [79]. For instance, Zheng and colleagues showed that AuNCs can be designed to demonstrate passive tumor targeting behavior comparable to that of larger NPs. GSH-coated AuNCs reached passive tumor uptake levels of 2–3
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Published 30 Sep 2024

A low-kiloelectronvolt focused ion beam strategy for processing low-thermal-conductance materials with nanoampere currents

  • Annalena Wolff,
  • Nico Klingner,
  • William Thompson,
  • Yinghong Zhou,
  • Jinying Lin and
  • Yin Xiao

Beilstein J. Nanotechnol. 2024, 15, 1197–1207, doi:10.3762/bjnano.15.97

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  • cross sections and TEM lamellae of biological samples as well as of other thermally low conductive materials such as polymers [1][2][3][4][5][6][7][8][9][10][11][12][13]. The easily induced heat damage is increasingly being reported [3][6][14][15][16][17]. Despite the importance of this topic, there is
  • 160 ps, just before the arrival of the next ion in a 1 nA beam, the central region below the impact point of that ion, has cooled down to 80 °C. Figure 2 shows the contour plots of the mid-plane collagen sample temperature at t = 160 ps for a 5 keV ion. The ion cascade cumulative and adjacent heating
  • temperature of ΔTskin = 7.5 K. The model predicts that much less heat damage will occur when using 5 keV energy ions despite using nanoampere range currents. This is in good agreement with the numerical modelling results and COMSOL simulations. Table 2 below shows the calculated results for 5 keV ions for
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Published 27 Sep 2024

Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers

  • Ömür Acet,
  • Pavel Kirsanov,
  • Burcu Önal Acet,
  • Inessa Halets-Bui,
  • Dzmitry Shcharbin,
  • Şeyda Ceylan Cömert and
  • Mehmet Odabaşı

Beilstein J. Nanotechnol. 2024, 15, 1189–1196, doi:10.3762/bjnano.15.96

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  • ; temperature- and pH-sensitive nanopolymer; Introduction Almost one in six deaths worldwide is from cancer, and cancer caused approximately 10 million deaths in 2020. Today, nanotechnology is emerging as an effective way to enable rapid diagnosis and treatment of cancer diseases [1][2][3]. The chemotherapy
  • the HeLa cancer cell line (CCL-2 ATCC). Cells were grown in full DMEM with stable glutamine, 4.5 g/L glucose (Life Technologies, Paisley, U.K.), 10% FBS (Life Technologies, Paisley, U.K.), 100 U/mL penicillin, and 0.1 mg/mL streptomycin (Millipore-Sigma, Burlington, MA, United States) at 37 °C in a
  • polyvinyl alcohol (PVA), 57.7 mg sodium dodecyl sulfate (SDS), and 46.9 mg NaHCO3 in 20 mL of water (solution A in Figure 1). For solution B, 0.2 g PVA and 0.2 g SDS were dissolved in 400 mL of water. The organic phase (solution C) was obtained by mixing and dissolving (30 min in a beaker) 0.8 mL 2
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Published 26 Sep 2024

AI-assisted models to predict chemotherapy drugs modified with C60 fullerene derivatives

  • Jonathan-Siu-Loong Robles-Hernández,
  • Dora Iliana Medina,
  • Katerin Aguirre-Hurtado,
  • Marlene Bosquez,
  • Roberto Salcedo and
  • Alan Miralrio

Beilstein J. Nanotechnol. 2024, 15, 1170–1188, doi:10.3762/bjnano.15.95

Graphical Abstract
  • diagnosed cancer in women and the second leading cause of cancer-related mortality in women [1][2]. Heritage is the most critical risk factor, and 15 to 20% of breast cancer is familiar [3]. One of the characteristics of breast cancer is that it can be wholly cured given an early diagnosis [4]. The
  • treatments for breast cancer, with different drug targets depending on the type of cancer. Progesterone- or estrogen-receptor-positive tumors are related to cancers with low mortality [14]. Another common target in chemotherapy is human epidermal growth factor receptor 2 (HER2). Only 15 to 20% of all tumors
  • are HER2-positive, overexpressing Erb-B2 receptor tyrosine kinase 2 (ERBB2) in the cell membrane. HER2 tumors are usually more aggressive than other ones, but the advantage is that their treatment is very effective [15]. Another chemotherapy target is the chemokine C-X-C motif receptor 7 (CXCR7) [16
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Published 19 Sep 2024

Quantum-to-classical modeling of monolayer Ge2Se2 and its application in photovoltaic devices

  • Anup Shrivastava,
  • Shivani Saini,
  • Dolly Kumari,
  • Sanjai Singh and
  • Jost Adam

Beilstein J. Nanotechnol. 2024, 15, 1153–1169, doi:10.3762/bjnano.15.94

Graphical Abstract
  • promising and expedient because it has the potential to address the current energy demand without making a hazardous impact on the environment [1][2]. Henceforth, researchers have made continuous efforts to design efficient and robust PV devices and solar cells. The systematic study of various solar cells
  • by separating it into two subsections, namely (a) material simulation using DFT and (b) device simulation using a macroscopic approach, which will be discussed in section Computational Methods. Structural and stability analysis The schematic atomistic model for monolayer Ge2Se2 is shown in Figure 2
  • each Ge and Se). More precisely, we can observe two sub-layers corresponding to a crystallogen (Ge) and a chalcogen (Se), which are designate as top and bottom moieties. From Figure 2, we can also notice that the structure of monolayer Ge2Se2 is identical to the puckered phosphorene (simple
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Published 11 Sep 2024

Introducing third-generation periodic table descriptors for nano-qRASTR modeling of zebrafish toxicity of metal oxide nanoparticles

  • Supratik Kar and
  • Siyun Yang

Beilstein J. Nanotechnol. 2024, 15, 1142–1152, doi:10.3762/bjnano.15.93

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  • range of substances that can be categorized as carbon-based, metal oxides, semiconductors, polymers, clays, emulsions, or metals [2]. Metal oxide nanoparticles (MONPs) are metallic oxides that exist within the nanoscale range and can be intentionally created or occur naturally [3]. Under the rapid
  • also checked through the “Prediction Reliability Tool” that employs the AD to our external prediction that is evaluated by three criteria: (1) The mean absolute error is calculated for leave-one-out predictions using the ten most similar training compounds for each query molecule. (2) The
  • . nano-qRASTR toxicity model To improve the statistical quality of the nano-QSTR models, we have employed read-across descriptors employing modeled descriptors. Later, all descriptors are merged together and employed for modeling using the BSS-MLR approach. Equation 2 presents the developed nano-qRASTR
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Published 10 Sep 2024

Photocatalytic methane oxidation over a TiO2/SiNWs p–n junction catalyst at room temperature

  • Qui Thanh Hoai Ta,
  • Luan Minh Nguyen,
  • Ngoc Hoi Nguyen,
  • Phan Khanh Thinh Nguyen and
  • Dai Hai Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1132–1141, doi:10.3762/bjnano.15.92

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  • industrial chemicals and energy. However, CH4 is a major precursor for tropospheric ozone, causing severe air pollution. Because of its rising atmospheric concentration, CH4 poses a global warming potential approximately thirty fold larger than that of carbon dioxide (CO2) [1][2][3]. Therefore, it is a
  • morphology of SiNWs is characterized by individual nanowires that bunch together in a highly ordered manner, resulting in well-oriented Si NW arrays perpendicular to the Si bulk surface. Figure 2 shows cross-sectional- and top-view SEM images of the as-prepared TiO2/SiNWs sample. The TiO2/SiNWs arrays were
  • provided from Sigma-Aldrich. Deionized (DI) water was used for cleaning steps. Si NWs and TiO2/Si NWs preparation First, a small piece (1 × 2 cm2) was cut from a commercial p-type Si wafer and washed several times using DI water, ethanol, and acetone in a sonication bath. Etching solution containing AgNO3
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Published 02 Sep 2024

Local work function on graphene nanoribbons

  • Daniel Rothhardt,
  • Amina Kimouche,
  • Tillmann Klamroth and
  • Regina Hoffmann-Vogel

Beilstein J. Nanotechnol. 2024, 15, 1125–1131, doi:10.3762/bjnano.15.91

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  • with respect to the Dirac point, the center of the Dirac cones [2]. The location of the Fermi level is a measure of the work function with respect to a different energy reference, the vacuum energy. This position can be tuned by gating [3] or by doping, for example, n-doping for graphene on SiC [4][5
  • ] and p-doping by Bi, Sb, and Au substrates [2]. Confining graphene to nanostructures [6][7], for example, to graphene nanoribbons (GNRs), that is, few nanometers wide stripes of graphene, opens additional possibilities of tuning the electronic properties by creating quantum-confined states [8] and
  • -dependent measurements. Experimental The experiments were conducted in an Omicron VT-SFM system (base pressure 2 × 10−10 mbar). The Au(111) single crystal substrate (Mateck GmbH) was cleaned by repeated Ar ion sputtering–annealing cycles. The cleanliness of the samples was checked by SFM measurements. Then
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Published 29 Aug 2024

Direct electron beam writing of silver using a β-diketonate precursor: first insights

  • Katja Höflich,
  • Krzysztof Maćkosz,
  • Chinmai S. Jureddy,
  • Aleksei Tsarapkin and
  • Ivo Utke

Beilstein J. Nanotechnol. 2024, 15, 1117–1124, doi:10.3762/bjnano.15.90

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  • . Keywords: focused electron beam-induced deposition; precursor; silver nanostructures; Introduction Direct writing with an electron beam allows for single-step and maskfree 3D printing of sophisticated nanostructures at the nanoscale [1][2][3][4]. The process relies on the electron beam-induced
  • (Strem Chemicals, CAS 148630-66-4), with a stoichiometry of Ag/P/F/O/C = 1:1:6:2:8 was evaporated using a fully integrated custom-built gas injection system (GIS) consisting of chemically inert steel [28]. No injection needles were used. The components of the GIS that were in direct contact with the
  • for experiments to roughly 2 h since the evaporated precursor would start to crystallize at the crucible cap. Heating of the sample was realized with a Kleindiek MHS (Micro Heating Stage), which allowed us to keep the substrate temperature constant at 60 °C throughout the whole experiment. The
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Published 26 Aug 2024

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

  • Damai Ria Setyawati,
  • Fransiska Christydira Sekaringtyas,
  • Riyona Desvy Pratiwi,
  • A’liyatur Rosyidah,
  • Rohimmahtunnissa Azhar,
  • Nunik Gustini,
  • Gita Syahputra,
  • Idah Rosidah,
  • Etik Mardliyati,
  • Tarwadi and
  • Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

Graphical Abstract
  • application of nanoscale systems with unique physicochemical properties, including small size, large specific surface area, high reactivity, and quantum effects of the nanoparticles (NPs) [1][2]. Nanomedicine is specifically designated for therapeutics (drug delivery), diagnostics, and imaging, as well as for
  • effects of TiO2 NPs, with diameters around 20 and 200 nm, and SiO2 NPs on proliferation, fibrosis, adhesion, and migration of LX-2 cells as a model of HSC activation were studied. The results show that the internalization of both TiO2 NPs and SiO2 NPs suppressed classical outcomes of cellular fibrosis
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Published 23 Aug 2024

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

  • Shakhzodjon Uzokboev,
  • Khojimukhammad Akhmadbekov,
  • Ra’no Nuritdinova,
  • Salah M. Tawfik and
  • Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

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  • environment, and industry [1][2][3][4][5][6][7]. When employing these technical devices, users can chose user-friendly, cost-effective, sensitive, and error-free detecting instruments [8]. The field of biosensors has received a lot of interest over the last years because of their amazing capacity for early
  • -based composite nanoparticles, which provides a comprehensive overview of nanoparticles and their uses, especially in sensing applications (Figure 2). Moreover, characterization techniques of biopolymeric nanoparticles and their importance for drug delivery and sensing methods will be reviewed. In
  • several hours for results. The development of compact and portable miniaturized sensors has enabled the detection of different biomarkers for continuous, real-time human health monitoring [1][2]. Temperature, heart rate, electrical conductivity, dehydration, and glucose are some of the indicators that
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Published 22 Aug 2024

Signal generation in dynamic interferometric displacement detection

  • Knarik Khachatryan,
  • Simon Anter,
  • Michael Reichling and
  • Alexander von Schmidsfeld

Beilstein J. Nanotechnol. 2024, 15, 1070–1076, doi:10.3762/bjnano.15.87

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  • structure. By the fit of a model to the measured time-domain signal, all parameters governing the interferometric displacement signal can precisely be determined. It is demonstrated, that such an analysis specifically allows for the calibration of the cantilever oscillation amplitude with 2% accuracy
  • . Keywords: amplitude calibration; displacement detection; force microscopy; interferometer signal; NC-AFM; Introduction Optical interferometry is a reliable technique utilizing light waves to measure distance and displacement with high precision [1][2]. With the light wavelength as the length standard, a
  • and cavity beams yields, as the intensity measured at the detector position, By introducing the incoming light intensity , where c is the speed of light in vacuum and ε0 is the vacuum permittivity, and the reflectivities Rf = (rf)2, Rc = (rc)2 and cavity loss Sloss(2d) = (sloss(2d))2, Equation 1 is
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Published 20 Aug 2024

Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP

  • Sree Satya Bharati Moram,
  • Chandu Byram and
  • Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1054–1069, doi:10.3762/bjnano.15.86

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  • size and composition, making it a preferred choice for nanomaterials synthesis [2][3][4][5]. The process involves laser plasma interacting with a metal in a liquid; it excites electrons, which then generates atomic vibrations within a few picoseconds, causing rapid heating, melting, and explosive
  • (TEM) was performed with a JEM-2100F (JEOL, Japan). TEM grids were prepared by drop casting 2 µL of NPs onto the grids. Raman/SERS spectra were collected using a portable Raman spectrometer (B&W Tek) with an excitation wavelength of 785 nm, 10 mW of laser power, 5 s of collection time, and three
  • studies of as-synthesized nanoparticles Transmission electron microscopy analysis was implemented to study the size and shape of laser-fabricated NPs. Figure 2 shows the TEM images of Ag NPs synthesized in DW at different laser wavelengths: (a) 355, (b) 532, and (c) 1064 nm. It should be noted that the
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Published 19 Aug 2024

Interface properties of nanostructured carbon-coated biological implants: an overview

  • Mattia Bartoli,
  • Francesca Cardano,
  • Erik Piatti,
  • Stefania Lettieri,
  • Andrea Fin and
  • Alberto Tagliaferro

Beilstein J. Nanotechnol. 2024, 15, 1041–1053, doi:10.3762/bjnano.15.85

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  • to describe the study of materials at the nanoscale [2]. Afterwards, nanosized and nanostructured carbon species have attracted great interest thanks to their intrinsic properties and easy functionalization [3]. The utilization of nanocarbon species has been widely deployed in advanced medical
  • carbon materials has several members with peculiar properties, namely, (i) graphene-related materials, (ii) CNTs, and (iii) nanodiamonds (NDs) as shown in Figure 2. All nanosized carbon materials show remarkable properties regarding both thermal and electronic conduction, but they should be treated
  • in Table 2, individual SWCNTs or MWCNTs show incredibly good mechanical and conduction properties. Nevertheless, individual CNTs are rare, and most applications are based on CNT bundles, which are difficult to homogenously disperse in polymeric matrices, and whose properties are not comparable with
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Published 16 Aug 2024

Bolometric IR photoresponse based on a 3D micro-nano integrated CNT architecture

  • Yasameen Al-Mafrachi,
  • Sandeep Yadav,
  • Sascha Preu,
  • Jörg J. Schneider and
  • Oktay Yilmazoglu

Beilstein J. Nanotechnol. 2024, 15, 1030–1040, doi:10.3762/bjnano.15.84

Graphical Abstract
  • resistance (TCR). These properties are advantageous for new bolometric sensors with high voltage responsivity and broadband absorption from the infrared (IR) to the terahertz spectrum. Preliminary performance evaluations have shown current and voltage responsivities of 2 mA/W and 30 V/W, respectively, in
  • for non-cryogenic IR microbolometer technology, carbon nanotubes (CNTs) have emerged as highly promising candidates [2] with broadband blackbody absorption [3], high resistance perpendicular to the CNT orientation [4], low lateral thermal conductivity [5], a high temperature coefficient of resistance
  • presented in the conference proceedings [12]. This configuration 1 (called sample 1) had additional parasitic contact resistances to the M-shaped CNT block. The new configuration 2 (called sample 2) used direct Au whisker contacts to the CNT block with much lower contact resistances for reliable
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Published 15 Aug 2024

Entry of nanoparticles into cells and tissues: status and challenges

  • Kirsten Sandvig,
  • Tore Geir Iversen and
  • Tore Skotland

Beilstein J. Nanotechnol. 2024, 15, 1017–1029, doi:10.3762/bjnano.15.83

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  • Food and Drug Administration (FDA) in 1995 [2]; this product has a similar therapeutic effect and less side effects than those obtained with the free drug. Later on, also other NPs have been approved for clinical use [1], but there is still a large need for new products. In addition to the development
  • invagination. However, even in high-impact articles one can see that conclusions are drawn based on insufficient evidence and thus might be wrong and misleading for the field. Also, addition of ruthenium red during fixation in preparation for EM is helpful to decide if a compound is internalized; see Figure 2
  • shown to be internalized by different endocytic mechanisms [58][59][60]. Uptake via caveolae may be a minor route; introduction of caveolae in Caco-2 cells by transfection with caveolin did not increase the uptake of cholera toxin [58]. Macropinocytosis and nanoparticle uptake Several of the NPs studied
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Published 12 Aug 2024

Can neutral clusters: a two-step G0W0 and DFT benchmark

  • Sunila Bakhsh,
  • Sameen Aslam,
  • Muhammad Khalid,
  • Muhammad Sohail,
  • Sundas Zafar,
  • Sumayya Abdul Wadood,
  • Kareem Morsy and
  • Muhammad Aamir Iqbal

Beilstein J. Nanotechnol. 2024, 15, 1010–1016, doi:10.3762/bjnano.15.82

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  • /bjnano.15.82 Abstract Electronic and structural properties of calcium clusters with a varying size range of 2–20 atoms are studied using a two-step scheme within the GW and density functional theory (DFT) with generalized gradient approximation (GGA). The GGA overestimates the binding energies, optimized
  • materials science (as an ionic deposition) [2]. The clusters of calcium are essential because they bridge the atomic and bulk materials; therefore, revealing their transition from micro- to macroscopic characteristics is a significant undertaking [3]. Being a divalent metal, the size transition of calcium
  • clusters occurs above the trimer cluster. Small calcium clusters (2–5) have been investigated using first-principles calculations incorporating the electron correlation effects [4][5][6][7]. In 3D cluster structures, it can be used in the manufacturing of coating materials, which is useful for high
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Published 08 Aug 2024

Atomistic insights into the morphological dynamics of gold and platinum nanoparticles: MD simulations in vacuum and aqueous media

  • Evangelos Voyiatzis,
  • Eugenia Valsami-Jones and
  • Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 995–1009, doi:10.3762/bjnano.15.81

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  • employed to study other metallic and metal oxide nanomaterials. Keywords: crystallization; gold; molecular dynamics; nanoparticles; platinum; Introduction Nanomaterials, that is, materials with dimensions in the range of 1–100 nm [1][2], are central to a variety of developments in science and technology
  • /evoyiatzis/Jupyter-Notebooks. Results and Discussion The radial number density distributions in selected Au and Pt NPs for two temperatures are shown in Figure 2. The NP diameters are 2 nm (Figure 2a,c) and 8 nm (Figure 2b,d). The considered temperatures for the Au NPs (Figure 2a,b) are 100 K (blue line) and
  • the spatial fluctuations around their mean atomic position. In all cases, δ becomes larger with increasing temperatures. For the Au NPs with a diameter larger than 2 nm, a sharp drop in the δ curves takes place between 1000 and 1100 K; the δ value becomes smaller than the critical value of 0.05, and a
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Published 07 Aug 2024

Recent progress on field-effect transistor-based biosensors: device perspective

  • Billel Smaani,
  • Fares Nafa,
  • Mohamed Salah Benlatrech,
  • Ismahan Mahdi,
  • Hamza Akroum,
  • Mohamed walid Azizi,
  • Khaled Harrar and
  • Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

Graphical Abstract
  • devices have gained significant importance across various domains, including the medical field, environmental monitoring, and the agricultural sector (Figure 1) [1][2]. In this context, biosensors have found widespread application in industries, particularly for food quality control and safety [3]. They
  • beneficial [18]. Additionally, biosensors have been used to detect SARS-CoV-2, which causes COVID-19-related severe respiratory distress [19][20]. For the accurate detection of COVID-19 RNA [21][22], proteins [23][24], and virus particles [25][26], various methods have been proposed, such as CRISPR systems
  • biorecognition layer, a transducer, and an amplifier (Figure 2). It typically consists of a semiconductor channel and three terminal electrodes named drain, source, and gate [37][49]. The biorecognition layer selectively binds the target biomolecule (analyte), such as enzymes, antibodies, and proteins in a
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Published 06 Aug 2024

Beyond biomimicry – next generation applications of bioinspired adhesives from microfluidics to composites

  • Dan Sameoto

Beilstein J. Nanotechnol. 2024, 15, 965–976, doi:10.3762/bjnano.15.79

Graphical Abstract
  • climbing capabilities of geckos launched over 20 years of intense scientific and engineering efforts to understand and industrially mimic this technology [2][3][4]. Coincidentally, in 2000, the same year that Autumn’s paper was published, the Nobel Prize for physics was awarded to Zhores Alferov and
  • designed biomimetic adhesives were discarded in favor of the more well-known and well-characterized mushroom-shaped fiber structures, and many groups developed similar shapes around the same time [2]. I will not cover the exact mechanisms by which these mushroom shapes have proven effective, as several
  • review articles have already been published on this topic [2][4]. However, for high normal strength and peel strength where directionality or easy off–on performance is not needed, this particular version of the biomimetic fibers tends to perform best. Our unique contributions to these general types of
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Published 05 Aug 2024
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