Development of a continuous process for α-thio-β-chloroacrylamide synthesis with enhanced control of a cascade transformation

Olga C. Dennehy, Valérie M. Y. Cacheux, Benjamin J. Deadman, Denis Lynch, Stuart G. Collins, Humphrey A. Moynihan and Anita R. Maguire

Beilstein J. Org. Chem. 2016, 12, 2511–2522. https://doi.org/10.3762/bjoc.12.246

Supporting Information

Supporting Information File 1: General information, experimental procedures, analytical data and copies of NMR spectra of all compounds.
Format: PDF Size: 1.4 MB Download

References

Article Citation
Download RIS (Reference Manager) Download BIB (BIBTEX)
Cited References
Download RIS (Reference Manager) Download BIB (BIBTEX)

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.

Format: PNG Size: 146.6 KB Download
Back To Article

Article is part of the issue

Automated chemical synthesis

Ian R. Baxendale, Marcus Baumann and Richard Bourne

Latest Articles

A versatile way for the synthesis of monomethylamines by reduction of N-substituted carbonylimidazoles with the NaBH4/I2 system

  1. Lin Chen,
  2. Xuan Zhou,
  3. Zhiyong Chen,
  4. Changxu Wang,
  5. Shunjie Wang and
  6. Hanbing Teng
  • Full Research Paper
  • Published 17 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1032–1039, doi:10.3762/bjoc.18.104

Electrochemical vicinal oxyazidation of α-arylvinyl acetates

  1. Yi-Lun Li,
  2. Zhaojiang Shi,
  3. Tao Shen and
  4. Ke-Yin Ye
  • Letter
  • Published 12 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1026–1031, doi:10.3762/bjoc.18.103

New azodyrecins identified by a genome mining-directed reactivity-based screening

  1. Atina Rizkiya Choirunnisa,
  2. Kuga Arima,
  3. Yo Abe,
  4. Noritaka Kagaya,
  5. Kei Kudo,
  6. Hikaru Suenaga,
  7. Junko Hashimoto,
  8. Manabu Fujie,
  9. Noriyuki Satoh,
  10. Kazuo Shin-ya,
  11. Kenichi Matsuda and
  12. Toshiyuki Wakimoto
  • Full Research Paper
  • Published 10 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1017–1025, doi:10.3762/bjoc.18.102

Isolation and biosynthesis of daturamycins from Streptomyces sp. KIB-H1544

  1. Yin Chen,
  2. Jinqiu Ren,
  3. Ruimin Yang,
  4. Jie Li,
  5. Sheng-Xiong Huang and
  6. Yijun Yan
  • Full Research Paper
  • Published 09 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 1009–1016, doi:10.3762/bjoc.18.101

Automated grindstone chemistry: a simple and facile way for PEG-assisted stoichiometry-controlled halogenation of phenols and anilines using N-halosuccinimides

  1. Dharmendra Das,
  2. Akhil A. Bhosle,
  3. Amrita Chatterjee and
  4. Mainak Banerjee
  • Full Research Paper
  • Published 09 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 999–1008, doi:10.3762/bjoc.18.100

Molecular diversity of the base-promoted reaction of phenacylmalononitriles with dialkyl but-2-ynedioates

  1. Hui Zheng,
  2. Ying Han,
  3. Jing Sun and
  4. Chao-Guo Yan
  • Full Research Paper
  • Published 08 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 991–998, doi:10.3762/bjoc.18.99

First example of organocatalysis by cathodic N-heterocyclic carbene generation and accumulation using a divided electrochemical flow cell

  1. Daniele Rocco,
  2. Ana A. Folgueiras-Amador,
  3. Richard C. D. Brown and
  4. Marta Feroci
  • Full Research Paper
  • Published 05 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 979–990, doi:10.3762/bjoc.18.98

Understanding the competing pathways leading to hydropyrene and isoelisabethatriene

  1. Shani Zev,
  2. Marion Ringel,
  3. Ronja Driller,
  4. Bernhard Loll,
  5. Thomas Brück and
  6. Dan T. Major
  • Full Research Paper
  • Published 04 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 972–978, doi:10.3762/bjoc.18.97

Electrochemical and spectroscopic properties of twisted dibenzo[g,p]chrysene derivatives

  1. Tomoya Imai,
  2. Ryuhei Akasaka,
  3. Naruhiro Yoshida,
  4. Toru Amaya and
  5. Tetsuo Iwasawa
  • Full Research Paper
  • Published 03 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 963–971, doi:10.3762/bjoc.18.96

Electroreductive coupling of 2-acylbenzoates with α,β-unsaturated carbonyl compounds: density functional theory study on product selectivity

  1. Naoki Kise and
  2. Toshihiko Sakurai
  • Full Research Paper
  • Published 02 Aug 2022
Graphical Abstract

Beilstein J. Org. Chem. 2022, 18, 956–962, doi:10.3762/bjoc.18.95

Latest Articles

Latest Thematic Issues

Enzymes in biosynthesis

Jeroen S. Dickschat

New Show Issue

Molecular and macromolecular electrochemistry: synthesis, mechanism, and redox properties

Shinsuke Inagi and Mahito Atobe

New Show Issue

Mechanochemistry III

José G. Hernández and Lars Borchardt

New Show Issue

Platform and enabling technologies in organic synthesis

Philipp Heretsch and
Andreas Kirschning

2021 Show Issue

Organic TADF materials design

Eli Zysman-Colman

2021 Call Show Issue

Earth-abundant 3d metal catalysis

Lutz Ackermann

2021 Show Issue

Supramolecular approaches to mediate chemical reactivity

Carmine Gaeta, Pablo Ballester
and Qi-Qiang Wang

2021 Show Issue

New advances in asymmetric organocatalysis

Radovan Šebesta

2020 Show Issue

GlycoBioinformatics

Kiyoko F. Aoki-Kinoshita,
Frédérique Lisacek, Niclas Karlsson, 
Daniel Kolarich and Nicolle Packer

2020 Show Issue
Browse all Thematic Issues

Other Beilstein-Institut Open Science Activities

Logo
Logo
Logo
Logo

Keep Informed

RSS Feed

Subscribe to our Latest Articles RSS Feed.

Subscribe

Follow the Beilstein-Institut

LinkedIn

Twitter: @BeilsteinInst