Preparation of imidazo[1,2-a]-N-heterocyclic derivatives with gem-difluorinated side chains

Layal Hariss, Kamal Bou Hadir, Mirvat El-Masri, Thierry Roisnel, René Grée and Ali Hachem
Beilstein J. Org. Chem. 2017, 13, 2115–2121. https://doi.org/10.3762/bjoc.13.208

Supporting Information

Supporting Information File 1: Experimental details and characterization data of new compounds with copies of 1H, 13C and 19F NMR spectra.
Format: PDF Size: 6.6 MB Download

Cite the Following Article

Preparation of imidazo[1,2-a]-N-heterocyclic derivatives with gem-difluorinated side chains
Layal Hariss, Kamal Bou Hadir, Mirvat El-Masri, Thierry Roisnel, René Grée and Ali Hachem
Beilstein J. Org. Chem. 2017, 13, 2115–2121. https://doi.org/10.3762/bjoc.13.208

How to Cite

Hariss, L.; Hadir, K. B.; El-Masri, M.; Roisnel, T.; Grée, R.; Hachem, A. Beilstein J. Org. Chem. 2017, 13, 2115–2121. doi:10.3762/bjoc.13.208

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 113.2 KB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Justaud, F.; Grée, R. Development of the Meyer–Schuster Rearrangement on Propargylic Alcohols with Fluorinated Chains. European Journal of Organic Chemistry 2023, 26. doi:10.1002/ejoc.202300974
  • Zhong, W.; Zhao, C.; Huang, Q.; Wu, L.; Shi, J.; Li, J.; Lu, W.; Tang, F.; Zhu, L. I2/DTBP Promoted Synthesis of C3-Carbonylated Imidazopyridines from Chromones and 2-Aminopyridines via (3+2) Cycloaddition. Synthesis 2023, 55, 2570–2580. doi:10.1055/a-2058-0119
  • Ramarao, S.; Pothireddy, M.; Venkateshwarlu, R.; Moturu, K. M. V. R.; Siddaiah, V.; Kapavarapu, R.; Dandela, R.; Pal, M. Sonochemical Synthesis and In Silico Evaluation of Imidazo[1,2-a]Pyridine Derivatives as Potential Inhibitors of Sirtuins. Polycyclic Aromatic Compounds 2022, 43, 3741–3760. doi:10.1080/10406638.2022.2077774
  • El Kharrat, S.; Laurent, P.; Boiteau, L. Diastereoselective Synthesis of Perfluoroalkylmethyl‐Substituted 1,2,3,4‐Tetrahydroquinolines Derivatives through 1‐Iodo‐1,3‐bis(acetoxy) Synthons. European Journal of Organic Chemistry 2022, 2022. doi:10.1002/ejoc.202200126
  • Li, W.; Zhang, J.; Wang, M.; Dong, R.; Zhou, X.; Zheng, X.; Sun, L. Pyrimidine-fused Dinitrogenous Penta-heterocycles as a Privileged Scaffold for Anti-Cancer Drug Discovery. Current topics in medicinal chemistry 2022, 22, 284–304. doi:10.2174/1568026622666220111143949
  • Panda, J.; Raiguru, B. P.; Mishra, M.; Mohapatra, S.; Nayak, S. Recent Advances in the Synthesis of Imidazo[1,2‐a]pyridines: A Brief Review. ChemistrySelect 2022, 7. doi:10.1002/slct.202103987
  • Ghorbani-Choghamarani, A.; Taherinia, Z.; Heidarnezhad, Z.; Moradi, Z. Application of Nanofibers Based on Natural Materials as Catalyst in Organic Reactions. Journal of Industrial and Engineering Chemistry 2021, 94, 1–61. doi:10.1016/j.jiec.2020.10.028
  • Soulieman, A.; Ibrahim, R.; Barakat, Z.; Gouault, N.; Roisnel, T.; Boustie, J.; Grée, R.; Hachem, A. Synthesis of Novel Cyclic Nitrones with gem-Difluoroalkyl Side Chains Through Cascade Reactions. European Journal of Organic Chemistry 2020, 2020, 5741–5751. doi:10.1002/ejoc.202000972
  • Jadhav, N. H.; Sakate, S. S.; Shinde, D. R.; Chaskar, M. G.; Pawar, R. A transition metal-free cascade reaction using heterogeneous tin(IV)oxide catalyzed and iodine promoted synthesis of 3-aroylimidazo[1,2-a]pyridines. Tetrahedron Letters 2020, 61, 152250. doi:10.1016/j.tetlet.2020.152250
  • An, L.; Tong, F.-F.; Zhang, S.; Zhang, X. Stereoselective Functionalization of Racemic Cyclopropylzinc Reagents via Enantiodivergent Relay Coupling. Journal of the American Chemical Society 2020, 142, 11884–11892. doi:10.1021/jacs.0c04462
  • Saba, S.; Dos Santos, C. R.; Zavarise, B. R.; Naujorks, A. A. S.; Franco, M. S.; Schneider, A. R.; Scheide, M. R.; Affeldt, R. F.; Rafique, J.; Braga, A. L. Photoinduced, Direct C(sp2 )-H Bond Azo Coupling of Imidazoheteroarenes and Imidazoanilines with Aryl Diazonium Salts Catalyzed by Eosin Y. Chemistry (Weinheim an der Bergstrasse, Germany) 2020, 26, 4461–4466. doi:10.1002/chem.201905308
  • Boreux, A.; Lambion, A.; Campeau, D.; Sanita, M.; Coronel, R.; Riant, O.; Gagosz, F. Gold-catalyzed synthesis of β-trifluoromethylated α,β-unsaturated ketones from CF3-substituted propargylic carboxylates and their reactivity in Diels-Alder reactions. Tetrahedron 2018, 74, 5232–5239. doi:10.1016/j.tet.2018.05.054
Other Beilstein-Institut Open Science Activities