One-pot activation–alkynylation–cyclization synthesis of 1,5-diacyl-5-hydroxypyrazolines in a consecutive three-component fashion

Christina Görgen, Katharina Boden, Guido J. Reiss, Walter Frank and Thomas J. J. Müller

Beilstein J. Org. Chem. 2019, 15, 1360–1370. doi:10.3762/bjoc.15.136

Supporting Information

For experimental details of the optimization studies on intermediate 3a, on the cyclization step of 3a and 4b (compound 5b), on the consecutive three-component synthesis of compound 5b, experimental details of general procedure of the consecutive three-component synthesis and analytical data of 1,5-diacyl-5-hydroxypyrazolines 5, experimental details on the attempted dehydrative aromatization of compound 5b, and NMR spectra of the compounds 5, and for summaries on the crystal structure analyses of 5a, 5r, and 6a see Supporting Information File 1.

Supporting Information File 1: Experimental details, copies of NMR spectra and crystallographic data.
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Thomas J. J. Müller

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