Accelerating fragment-based library generation by coupling high-performance photoreactors with benchtop analysis

Quentin Lefebvre, Christophe Salomé and Thomas C. Fessard
Beilstein J. Org. Chem. 2020, 16, 982–988. https://doi.org/10.3762/bjoc.16.87

Supporting Information

Supporting Information File 1: Experimental part.
Format: PDF Size: 1.6 MB Download

Cite the Following Article

Accelerating fragment-based library generation by coupling high-performance photoreactors with benchtop analysis
Quentin Lefebvre, Christophe Salomé and Thomas C. Fessard
Beilstein J. Org. Chem. 2020, 16, 982–988. https://doi.org/10.3762/bjoc.16.87

How to Cite

Lefebvre, Q.; Salomé, C.; Fessard, T. C. Beilstein J. Org. Chem. 2020, 16, 982–988. doi:10.3762/bjoc.16.87

Download Citation

Citation data can be downloaded as file using the "Download" button or used for copy/paste from the text window below.
Citation data in RIS format can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Zotero.

Presentation Graphic

Picture with graphical abstract, title and authors for social media postings and presentations.
Format: PNG Size: 313.7 KB Download

Citations to This Article

Up to 20 of the most recent references are displayed here.

Scholarly Works

  • Martinelli, M.; Giorgiutti, C.; Fessard, T.; Lefebvre, Q. Introducing covalent warheads on spirocyclic sp2-sp3 fragments by innate C-H functionalization. Organic & biomolecular chemistry 2023, 21, 9230–9235. doi:10.1039/d3ob01746j
  • Lefebvre, Q.; Bocu, M.; Giorgiutti, C.; Fessard, T. C. Nickel‐Photoredox‐Catalyzed Synthesis of sp2−sp3 Fragments and the Impact of Bicycloalkane Isosteric Replacement on Their Physical‐Chemical Properties. Helvetica Chimica Acta 2023, 106. doi:10.1002/hlca.202200189
  • Santanilla, A. B.; Cook, G. Applications of High Throughput Chemistry to Medicinal Chemistry. The Power of High-Throughput Experimentation: Case Studies from Drug Discovery, Drug Development, and Catalyst Discovery (Volume 2); American Chemical Society, 2022; pp 3–21. doi:10.1021/bk-2022-1420.ch001
  • Candish, L.; Collins, K. D.; Cook, G. C.; Douglas, J.; Gómez-Suárez, A.; Jolit, A.; Keess, S. Photocatalysis in the Life Science Industry. Chemical reviews 2021, 122, 2907–2980. doi:10.1021/acs.chemrev.1c00416
  • Liu, D.; Liu, Z.; Ma, C.; Jiao, K.; Sun, B.; Wei, L.; Lefranc, J.; Herbert, S.; Mei, T. Nickel‐Catalyzed N‐Arylation of NH‐Sulfoximines with Aryl Halides via Paired Electrolysis. Angewandte Chemie 2021, 133, 9530–9535. doi:10.1002/ange.202016310
  • Liu, D.; Liu, Z.-R.; Ma, C.; Jiao, K.-J.; Sun, B.; Wei, L.; Lefranc, J.; Herbert, S.; Mei, T.-S. Nickel-Catalyzed N-Arylation of NH-Sulfoximines with Aryl Halides via Paired Electrolysis. Angewandte Chemie (International ed. in English) 2021, 60, 9444–9449. doi:10.1002/anie.202016310
  • Dallaston, M. A.; Houston, S. D.; Williams, C. M. Cubane, Bicyclo[1.1.1]pentane and Bicyclo[2.2.2]octane: Impact and Thermal Sensitiveness of Carboxyl-, Hydroxymethyl- and Iodo-substituents. Chemistry (Weinheim an der Bergstrasse, Germany) 2020, 26, 11966–11970. doi:10.1002/chem.202001658
Other Beilstein-Institut Open Science Activities