2 article(s) from Bregestovski, Piotr
Approach of the direct azologization of reported [60,61] serotonin 5-HT3R antagonists via replacement of a...
Jump to Scheme 1
Synthesis of the differently substituted quinoxaline azobenzene derivatives 5a and 5b via Baeyer –M...
Jump to Scheme 2
Synthesis of the methoxy-substituted quinoxaline derivative 12a via diazotization [66-69].
Jump to Scheme 3
General procedure for the synthesis of purine- and thienopyrimidine-substituted arylazobenzenes and...
Jump to Scheme 4
Synthesis of the thiomethyl-linked purine azobenzene 23 [62,63,72-74].
Jump to Scheme 5
Synthesis of the amide-linked azobenzene purine 28 [62,63,75-77].
Jump to Scheme 6
UV–vis absorption spectra measured at 50 µM in DMSO. Left: purine derivative 16c; right: azo-extend...
Jump to Figure 1
On the left panel representative traces of currents induced by the application of 3 µM 5HT (black t...
Jump to Figure 2
Beilstein J. Org. Chem. 2019, 15, 780–788, doi:10.3762/bjoc.15.74
The neurotransmitter GABA.
Synthesis of GABA-amide hydrochlorides 4a–c and 6a–f. (i) THF, reflux; (ii) MeOH, HCl (5%); (iii) T...
Effect of 7b on GABAA-receptor activation. (A) Superimposed traces of whole-cell currents induced b...
Absence of GABAA-receptor activation on application of 4c. Top traces: Examples of whole-cell curre...
Jump to Figure 3
Variation of EC50 values with the number n of methylene units separating the amide and the ammonium...
Jump to Figure 4
Effect of 7d on GABAA-receptor activation. (A,B) Superimposed traces of whole-cell currents induced...
Jump to Figure 5
Beilstein J. Org. Chem. 2013, 9, 406–410, doi:10.3762/bjoc.9.42
Subscribe to our Latest Articles RSS Feed.
Register and get informed about new articles.
Follow the Beilstein-Institut