/ Home
/ SUBMISSION

/ The BJOC
/ Diamond Open Access
/ Journal Statistics
/ Editorial Board
/ Community
/ Call for papers

/ Latest Articles
/ Most accessed
/ Thematic issues
/ Featured collections
/ Volumes
/ Authors

/ E-Alerts

/ BlueSky
/ LINKEDIN
/ Mastodon
/ RSS FEED

Empty search

Article Type

Publication Date Range

Search Tips

This search combines search strings from the content search (i.e. "Full Text", "Author", "Title", "Abstract", or "Keywords") with "Article Type" and "Publication Date Range" using the AND operator.

Search Examples

aromatic	the word “aromatic”
aromatic aldehyde	the word “aromatic” OR “aldehyde”
+aromatic +aldehyde	both words “aromatic” AND “aldehyde”
+aromatic -aldehyde	the word “aromatic” but NOT “aldehyde”
“aromatic aldehyde”	the exact phrase “aromatic aldehyde”
benz*	words which begin with “benz”, such as “benzene” or “benzyl”
benz*yl	words that begin with “benz” and end with “yl”, such as “benzyl” or “benzoyl”
benzyl~	words that are close to the word “benzyl”, such as “benzoyl” (i.e., fuzzy search)

BROWSE
Latest Articles
Most accessed
thematic issues
Featured Collections
volumes
authors

BROWSE

Latest Articles Most Accessed Thematic Issues Featured Collections Volumes Authors

Author

2 article(s) from Fernandes, Manuel A

Preparation of 3-(alkylamino)imidazo[1,2-a]pyridine-2-carbaldehydes via Kornblum oxidation and unexpected ring-opening reactions of the corresponding alcohols under oxidative conditions

Sandile J. Mkhize,
Memory Zimuwandeyi,
Manuel A. Fernandes,
Amanda L. Rousseau and
Moira L. Bode

Beilstein J. Org. Chem. 2026, 22, 763–770, doi:10.3762/bjoc.22.58

PDF

Graphical Abstract

Figure 1: Examples of biologically active imidazo[1,2-a]pyridines.

Jump to Figure 1

Figure 2: Compounds envisaged for synthesis.

Jump to Figure 2

Scheme 1: Preparation of methyl esters 13 versus unsubstituted derivatives 12 under various conditions. Metho...

Jump to Scheme 1

Scheme 2: Ester hydrolysis and in situ decarboxylation.

Jump to Scheme 2

Figure 3: Previously reported 3-amino-2-carboxylic acid derivatives.

Jump to Figure 3

Scheme 3: Ester reduction to the corresponding alcohols. Reaction yields are provided in parentheses.

Jump to Scheme 3

Figure 4: Single crystal X-ray structure of 18a. ORTEP diagram drawn at 50% probability level.

Jump to Figure 4

Scheme 4: Oxidative ring-opening with loss of one carbon atom. Yields are provided in parentheses.

Jump to Scheme 4

Scheme 5: Oxidative conditions applied to decarboxylated compound 12b.

Jump to Scheme 5

Figure 5: Different oxidative cleavage products obtained under different conditions.

Jump to Figure 5

Scheme 6: Unexpected aldehyde formation from tosylation reaction.

Jump to Scheme 6

Scheme 7: Kornblum oxidation to give imidazo[1,2-a]pyridine-2-carbaldehydes 20. Yield over two steps from the...

Jump to Scheme 7

Scheme 8: Reductive amination reactions to give target molecules 8.

Jump to Scheme 8

Album

Supp Info

Full Research Paper

Published 19 May 2026

Full text

Total synthesis of ent-pavettamine

Memory Zimuwandeyi,
Manuel A. Fernandes,
Amanda L. Rousseau and
Moira L. Bode

Beilstein J. Org. Chem. 2021, 17, 1440–1446, doi:10.3762/bjoc.17.99

PDF

Graphical Abstract

Figure 1: Structure of pavettamine 1 and its enantiomer 2.

Jump to Figure 1

Scheme 1: Established route for the synthesis of intermediate 4 [1].

Jump to Scheme 1

Scheme 2: Alternative route. Reaction conditions: a) TrCl, pyridine, rt, overnight, 100%; b) DMAP, imidazole,...

Jump to Scheme 2

Figure 2: Crystal structure of compound 9.

Jump to Figure 2

Scheme 3: Sequence showing the source of compound 9.

Jump to Scheme 3

Scheme 4: Stereoselective reduction of intermediate 8 as key step towards intermediate 4. Reaction conditions...

Jump to Scheme 4

Figure 3: Single crystal X-ray structure of compound 4.

Jump to Figure 3

Scheme 5: Synthesis of the C₅ fragments from intermediate 4. Reaction conditions: a) i) TFAA, collidine, 0 °C...

Jump to Scheme 5

Scheme 6: Synthesis of ent-pavettamine as the TFA salt 28. Reaction conditions: a) IBX, DMSO, rt, overnight, ...

Jump to Scheme 6

Album

Supp Info

Full Research Paper

Published 10 Jun 2021

Full text

Other Beilstein-Institut Open Science Activities

/ Help / Support & Contact / E-Alerts / Privacy Policy / Terms & Conditions / Impressum