3 article(s) from Komaki, Hisayuki
Graphical Abstract
Figure 1: Structures of 1–6.
Figure 2: COSY, key HMBC and NOESY correlations of 1–5.
Figure 3: 1H NMR spectra and partial chemical shift assignments for MPA esters 4'a–4'd. Upper: (R)-MPA acylat...
Figure 4: Chiral phase HPLC analysis of methyl ester 4'. Italicized numbers indicate peak areas.
Figure 5: COSY and key HMBC correlations observed for 6.
Figure 6: ΔδH(S-R) values in ppm calculated from PGME amides 6a and 6b.
Figure 7: Selected examples of the related compounds derived from the strains in the genus Streptomyces (a) a...
Graphical Abstract
Figure 1: Structures of pseudosporamide (1) and pseudosporamicins A–C (2–4).
Figure 2: COSY, key HMBC and ROESY correlations of pseudosporamide (1).
Figure 3: 1H NMR ΔδS−R values for PGME amides 5a and 5b obtained from compound 1.
Figure 4: The opposite axial chirality around the biaryl C-6–C-7'' bond influenced by the C-2 configuration i...
Figure 5: The experimental and calculated ECD spectra in MeCN.
Figure 6: COSY, key HMBC and NOESY correlations of compound 2.
Figure 7: NOESY correlations for the spiroacetal moiety of compound 2.
Figure 8: Selected examples of oligomycin-class metabolites from actinomycetes.
Graphical Abstract
Figure 1: The structure of butyrolactol A (1).
Figure 2: Cyanobacterial polyketides bearing a tert-butyl group.
Figure 3: Actinomycete metabolites possessing a contiguous 1,2-diol system.
Figure 4: Feeding experiments of 13C-labeled precursors into 1 detected by 2D-INADEQUATE NMR experiments. (a)...
Figure 5: Organization of the biosynthesis gene cluster for 1. Blue, transcriptional regulator; pink, PKS for...
Figure 6: Biosynthetic pathway of hydroxymalonyl-ACP. Adapted from [24].
Figure 7: Incorporation of L-valine-d8 into 1. (a) 1H NMR spectrum of natural 1 and 2H NMR spectrum of L-vali...
Figure 8: Incorporation of 13C- and 2H-labeled precursors into 1.