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Beilstein J. Org. Chem. 2021, 17, 558–568, doi:10.3762/bjoc.17.50
Structure of biologically active phthalazine derivatives.
Synthetic route to aminophthalazinones 5 and 6.
Proposed catalytic cycles for the amination of 4-bromophthalazinones of type 3 (Phthal: phthalazino...
Synthesis of 4-amino- and 4-polyaminophthalazinones 5 and 6 (the yields refer to the isolated compo...
The phthalazinone derivatives that were used to test the complexation of Cu(II) ions.
The proposal of the fragmentation pathway of the Cu(II) complex with compound 7.
Structure of complex 17.
Molecular structure of complex 17 with atom numbering scheme. The anisotropic displacement paramete...
Determination of relative cell viability (% of control) in different cell lines (HT-29; PC-3 and L-...
Cytotoxic properties of the phthalazinone derivatives expressed as IC50 after 72 h of cell treatmen...
Beilstein J. Org. Chem. 2016, 12, 1229–1235, doi:10.3762/bjoc.12.117
Synthesis of aminophosphonates 3Aa–j, 3Ba–e, 3Ca–d, 3Cg, aminophosphonic acids 4a, 4c and hydroxyph...
Normalized electronic absorption and emission spectra of 3Aj and pyrene in chloroform (c = 1 μM).
Emission spectra of compound 3Aj in various solvents. The spectra are normalized at ≈378 nm (pyrene...
IC50 values of studied compounds.