2 article(s) from Lechel, Tilman
Discovery of the LANCA three-component reaction. The reaction of pivalonitrile (1) with lithiated m...
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Proposed mechanism of the LANCA three-component reaction to β-ketoenamides KE and pyridin-4-ol deri...
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One-pot preparation of pyridin-4-ols PY and their subsequent transformations to highly substituted ...
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Synthesis of β-ketoenamides KE by the LANCA three-component reaction of alkoxyallenes, nitriles and...
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β-Ketoenamides KE36–43 derived from enantiopure components.
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Bis-β-ketoenamides KE44–46 derived from aromatic dicarboxylic acids.
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Conversion of alkyl propargyl ethers E into aryl-substituted β-ketoenamides KEAr and selected produ...
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Condensation of LANCA-derived β-ketoenamides KE with ammonium salts to give 5-alkoxy-substituted py...
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Synthesis of PM31–35 from β-ketoenamides KE37, KE38, KE40, KE41 and KE78 obtained by method A (NH4O...
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Synthesis of bis-pyrimidine derivatives PM36, PM39 and PM40 from β-ketoenamides KE44–46 by method A...
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Functionalization of pyrimidine derivatives PM through selenium dioxide oxidations of PM5, PM9, PM15...
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Conversion of 2-vinyl-substituted pyrimidine PM7 into aldehyde PM50; (NMO = N-methylmorpholine N-ox...
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Deprotection of 5-alkoxy-substituted pyrimidines PM2, PM20 and PM29 and conversion into nonaflates ...
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Palladium-catalyzed coupling reactions of PM54 and PM12 giving rise to new pyrimidine derivatives P...
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Synthesis of pyrimidyl-substituted pyridyl nonaflate PM60.
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Condensation of LANCA-derived β-ketoenamides KE with hydroxylamine hydrochloride leading to pyrimid...
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Reactions of β-ketoenamides KE15 and KE7 with hydroxylamine hydrochloride leading to pyrimidine N-o...
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Structures of pyrimidine N-oxides PO30–33 derived from β-ketoenamides KE43, KE45, KE78 and KE80.
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Reduction of PO4 to PM5 and Boekelheide rearrangements of PO13, PO14, PO4 and PO30 to 4-acetoxymeth...
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Deprotection of 4-acetoxymethyl-substituted pyrimidine derivatives PM61 and PM63, oxidations to for...
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Synthesis of pyrimidinyl-substituted alkyne PM74 and conversion into furopyrimidine PM75 and Sonoga...
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Trifluoroacetic acid-promoted conversion of LANCA-derived β-ketoenamides KE into oxazoles OX and 1,...
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Conversion of β-ketoenamide KE79 into oxazole OX16 and transformation into 5-styryl-substituted oxa...
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Mechanisms of the formation of 1,2-diketones DK and of acetyl-substituted oxazole derivatives OX.
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Hydrogenolyses of benzyloxy-substituted β-ketoenamides KE52 and KE54 to 1,2-diketone DK14 and to di...
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Conversions of 2,4-dicyclopropyl-substituted oxazole OX7 into oxazole derivatives OX18–20 (PPA = po...
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Syntheses of vinyl and ethynyl-substituted oxazole derivatives OX21 and OX23 and their palladium-ca...
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Synthesis of C3-symmetric oxazole derivative OX28 and the STM current image of its 1-phenyloctane s...
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Condensation of 1,2-diketones DK with o-phenylenediamine to quinoxalines QU1–7 (CAN = cerium ammoni...
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The LANCA three-component reaction leading to β-ketoenamides KE and the structure of functionalized...
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Beilstein J. Org. Chem. 2019, 15, 655–678, doi:10.3762/bjoc.15.61
Deprotection of 3-alkoxypyridinols 1 to pyridine-3,4-diols 2. aMethod a: Pd/C, H2, MeOH, rt, 1 d; b...
X-ray crystal structure of compound 2c/2c′.
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Conversion of pyridine-3,4-diols 2 into pyridinediyl bistriflates or -nonaflates 3. a) Et3N, Rf2O, ...
Sonogashira couplings of pyridinediyl bis(perfluoroalkanesulfonates) 3. a) Pd(PPh3)4 [or Pd(OAc)2/P...
Absorption and fluorescence spectra of compounds 4b and 4c.
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Beilstein J. Org. Chem. 2010, 6, No. 42, doi:10.3762/bjoc.6.42
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