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3 article(s) from Murlykina, Maryna V

Ultrasonic-assisted unusual four-component synthesis of 7-azolylamino-4,5,6,7-tetrahydroazolo[1,5-a]pyrimidines

Yana I. Sakhno,
Maryna V. Murlykina,
Oleksandr I. Zbruyev,
Anton V. Kozyryev,
Svetlana V. Shishkina,
Dmytro Sysoiev,
Vladimir I. Musatov,
Sergey M. Desenko and
Valentyn A. Chebanov

Full Research Paper
Published 27 Feb 2020

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1. Graphical Abstract
2. Scheme 1: Synthesis of tetrahydroazolopyrimidine derivatives.
  
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3. Scheme 2: Various multicomponent reactions involving pyruvic acids (pyruvates) and different α-aminoazoles.
  
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4. Scheme 3: Synthesis of 4-arylamino-substituted tetrahydroquinolines.
  
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5. Scheme 4: Ultrasound-assisted multicomponent reactions of 3-amino-1,2,4-triazole or 5-amino-1H-pyrazole-4-car...
  
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6. Scheme 5: Synthesis of 3-cyano-7-(4-methoxyphenyl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-5-carboxylic acid (7)....
  
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7. Scheme 6: Proposed reaction mechanism.
  
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8. Figure 1: Alternative structures A and B for the tetrahydroazolopyrimidines 4.
  
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9. Figure 2: Molecular structure of ethyl 5-(4-bromophenyl)-3-cyano-7-((4-cyano-1H-pyrazol-5-yl)amino)-4,5,6,7-t...
  
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10. Figure 3: Chains of 4g molecules in the crystal phase.
  
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Graphical Abstract

Beilstein J. Org. Chem. 2020, 16, 281–289, doi:10.3762/bjoc.16.27

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Doebner-type pyrazolopyridine carboxylic acids in an Ugi four-component reaction

Maryna V. Murlykina,
Oleksandr V. Kolomiets,
Maryna M. Kornet,
Yana I. Sakhno,
Sergey M. Desenko,
Victoriya V. Dyakonenko,
Svetlana V. Shishkina,
Oleksandr A. Brazhko,
Vladimir I. Musatov,
Alexander V. Tsygankov,
Erik V. Van der Eycken and
Valentyn A. Chebanov

Full Research Paper
Published 12 Jun 2019

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1. Graphical Abstract
2. Scheme 1: An overview of heterocyclic acids used in the Ugi reaction.
  
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3. Scheme 2: Synthesis of pyrazolopyridine carboxylic acids 4 [45] and 7 [45] in Doebner-type reaction.
  
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4. Figure 1: Molecular structure of N-(2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl)-6-(4-methoxyphenyl)-3-...
  
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Graphical Abstract

Beilstein J. Org. Chem. 2019, 15, 1281–1288, doi:10.3762/bjoc.15.126

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New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized

Maryna V. Murlykina,
Maryna N. Kornet,
Sergey M. Desenko,
Svetlana V. Shishkina,
Oleg V. Shishkin,
Aleksander A. Brazhko,
Vladimir I. Musatov,
Erik V. Van der Eycken and
Valentin A. Chebanov

Full Research Paper
Published 31 May 2017

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1. Graphical Abstract
2. Scheme 1: Aminoazoles in GBB-3CR and Ugi-4CR.
  
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3. Scheme 2: Reactivity of 5-amino-N-aryl-1H-pyrazole-4-carboxamide and 3-amino-5-methylisoxazole in GBB-3CR and...
  
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4. Figure 1: Alternative structures A and B for compounds 4 and 6.
  
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5. Figure 2: Selected data of HSQC and HMBC experiments for compound 4a.
  
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6. Figure 3: Molecular structure of 3-(tert-butylamino)-2-(4-chlorophenyl)-N-(4-fluorophenyl)-1H-imidazo[1,2-b]p...
  
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7. Figure 4: Selected data of NOE and HSQC experiments for compound 9d.
  
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8. Figure 5: Molecular structure of N-(2-(tert-butylamino)-1-(4-chlorophenyl)-2-oxoethyl)-N-(5-methylisoxazol-3-...
  
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Graphical Abstract

Beilstein J. Org. Chem. 2017, 13, 1050–1063, doi:10.3762/bjoc.13.104

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