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Beilstein J. Org. Chem. 2025, 21, 1480–1488, doi:10.3762/bjoc.21.110
Graphical Abstract
Scheme 1: Background and conception.
Scheme 2: Reaction scope of iodonium salts 1 and isonitriles. aReaction conditions: isonitrile (0.2 mmol), io...
Scheme 3: Selectivity experiments and scope of unsymmetrical iodoniums salts. aReaction conditions: 2-isocyan...
Scheme 4: Proposed reaction mechanism.
Beilstein J. Org. Chem. 2019, 15, 1962–1973, doi:10.3762/bjoc.15.191
Figure 1: Examples of some commercially available pharmaceuticals and agrochemicals containing the benzimidaz...
Figure 2: Formation of cationic species by protonation of 5-formyl-4-methylimidazole in TfOH and their reacti...
Figure 3: Benzimidazoles 1–8 used in this study.
Scheme 1: Reaction of 2-acetylbenzimidazole (2) with TfOH and benzene.
Scheme 2: Reactions of hydroxymethyl-substituted benzimidazole 7 and 8 with TfOH and benzene.
Scheme 3: Reaction mechanism of the formation of compounds 9–11.
Scheme 4: Reaction mechanism of the formation of compounds 12.